Abstract
Across 20 vaccine breakthrough cases detected at our institution, all 20 (100%) infections were due to variants of concern (VOCs) and had a median Ct of 20.2 (IQR, 17.1-23.3). When compared with 5174 contemporaneous samples sequenced in our laboratory, VOCs were significantly enriched among breakthrough infections (P < .05).
Keywords: SARS-CoV-2; sequencing; vaccine breakthrough; variants of concern.
All Keywords
【저자키워드】 SARS-CoV-2, Sequencing, variants of concern, Vaccine breakthrough, 【초록키워드】 Vaccine, VoC, Sequencing, Infection, variants of concern, variants, Laboratory, VOCs, breakthrough infections, Breakthrough infection, sequenced, significantly, median, IQR, 【제목키워드】 coronavirus 2, respiratory, concern, Washington, state,
【저자키워드】 SARS-CoV-2, Sequencing, variants of concern, Vaccine breakthrough, 【초록키워드】 Vaccine, VoC, Sequencing, Infection, variants of concern, variants, Laboratory, VOCs, breakthrough infections, Breakthrough infection, sequenced, significantly, median, IQR, 【제목키워드】 coronavirus 2, respiratory, concern, Washington, state,
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우리 기관에서 발견된 20건의 백신 혁신 사례에서 20건(100%) 감염은 모두 우려 변종(VOC)으로 인한 것이며 Ct 중앙값은 20.2(IQR, 17.1-23.3)였습니다. 우리 실험실에서 시퀀싱된 5174개의 동시 샘플과 비교할 때 VOC는 돌발성 감염에서 상당히 풍부했습니다(P < .05).
{{ 키워드: }} SARS-CoV-2; 시퀀싱; 백신 돌파구; 우려의 변종.