While several alternatives to cyclophosphamide have been proposed for refractory eosinophilic granulomatosis with polyangiitis (EGPA), therapeutic options are limited in patients with chronic infections. We report a case of refractory EGPA complicated by invasive aspergillosis and chronic hepatitis B. Although multiple immunosuppressants, including cyclophosphamide, were not effective, tacrolimus was used successfully to control disease without exacerbating concomitant infections in the long term. Tacrolimus could be an alternative choice in the treatment of EGPA, especially when aggressive immunosuppression is unfeasible.
All Keywords
【저자키워드】 tacrolimus, Chronic Hepatitis B, invasive aspergillosis, eosinophilic granulomatosis with polyangiitis, calcineurin inhibitor,
【저자키워드】 tacrolimus, Chronic Hepatitis B, invasive aspergillosis, eosinophilic granulomatosis with polyangiitis, calcineurin inhibitor,