Because of the current COVID-19-pandemic, the world is currently being held hostage in various lockdowns. ACE2 facilitates SARS-CoV-2 cell-entry, and is at the very center of several pathophysiological pathways regarding the RAAS, CS, KKS, T2DM, and IL-6. Their interactions with severe COVID-19 complications (e.g. ARDS and thrombosis), and potential therapeutic targets for pharmacological intervention, will be reviewed.
All Keywords
【저자키워드】 COVID-19, thrombosis, interleukin-6, complement, diabetes, angiotensin-converting enzyme 2, Renin angiotensin aldosterone system, Kallikrein-kinin system,
【저자키워드】 COVID-19, thrombosis, interleukin-6, complement, diabetes, angiotensin-converting enzyme 2, Renin angiotensin aldosterone system, Kallikrein-kinin system,