Abstract
This study investigated the immune response and outcome of BNT162b2 vaccination among 12 staff at a hospital in Fukushima, Japan. Blood samples were collected from participants before their first vaccination, with subsequent sampling performed during the participants’ work days for six weeks thereafter. Antibody titers peaked 6-13 days after the second vaccination (days 27-34 after the first), followed by a steady decrease. Six males had significantly lower peak antibody titers than six females (p = 0.016 with t-test); the older six (median age 53 years) had lower antibody titers than the younger six (median age 35 years) but without statistical significance (p value=0.24 with t-test).
Keywords: BNT162b2 vaccination; COVID-19; IgG antibody against SARS-CoV-2 spike protein.
【저자키워드】 COVID-19, BNT162b2 vaccination, IgG antibody against SARS-CoV-2 spike protein., 【초록키워드】 immune response, vaccination, hospital, outcome, BNT162b2, IgG antibody, SARS-CoV-2 spike protein, male, female, Antibody titer, Japan, Older, second vaccination, median age, statistical significance, t-test, blood sample, participant, first vaccination, significantly lower, decrease, performed, collected, subsequent, investigated, peaked, Fukushima, of BNT162b2, 【제목키워드】 BNT162b2 vaccine, immunization, SARS-CoV-2 spike protein, Pfizer/BioNTech, IgG antibody titer, peak,