The aim of this study was to describe the clinical evolution during 6 months of follow-up of adults recovered from COVID-19. We tried to determine how many met the definition of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). A total of 130 patients (51.0 ± 14 years, 34.6% female) were enrolled. Symptoms were common, participants reported a median number of 9 (IQR 5–14) symptoms. Fatigue was the most common symptom (61/130; 46.9%). Patients with fatigue were older 53.9 ± 13.5 years compared with 48.5 ± 13.3 years in those without fatigue ( p = 0.02) and had a longer length of hospital stay, 17 ± 14 days vs. 13 ± 10 days ( p = 0.04). There was no difference in other comorbidities between patients with fatigue and those without it, and no association between COVID-19 severity and fatigue. After multivariate adjustment of all baseline clinical features, only age 40 to 50 years old was positively associated with fatigue, OR 2.5 (95% CI 1.05–6.05) p = 0.03. In our survey, only 17 (13%) patients met the Institute of Medicine’s criteria for “systemic exertion intolerance disease,” the new name of ME/CFS. In conclusion, in some patients, the features of post-acute COVID-19 syndrome overlap with the clinical features of ME/CFS.
【저자키워드】 fatigue, Myalgic encephalomyelitis/chronic fatigue syndrome, symptoms of COVID-19, 【초록키워드】 COVID-19, COVID-19 severity, Comorbidity, Symptom, Symptoms, Clinical features, female, Patient, age, Follow-up, patients, clinical feature, association, criteria, Hospital stay, Older, overlap, 95% CI, no difference, syndrome, participant, clinical evolution, multivariate adjustment, feature, enrolled, reported, median, determine, baseline, IQR, 【제목키워드】 COVID-19, survey, Potential,