Abstract The world is currently experiencing a global pandemic caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), which causes severe respiratory disease similar to SARS. Previous studies have suggested that SARS‐CoV‐2 shares 79% and 96% sequence identity to SARS‐CoV and to bat coronavirus RaTG13, respectively, at the whole‐genome level. Furthermore, a series of studies have shown that SARS‐CoV‐2 induces clusters of severe respiratory illnesses (i.e., pneumonia, acute lung injury, acute respiratory distress syndrome) resembling SARS‐CoV. Moreover, the pathological syndrome may, in part, be caused by cytokine storms and dysregulated immune responses. Thus, in this work the recent literature surrounding the biology, clinical manifestations, and immunology of SARS‐CoV‐2 is summarized, with the aim of aiding prevention, diagnosis, and treatment for SARS‐CoV‐2 infection. Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has posed a serious threat to public health. Since the outbreak, numerous attempts have been taken to gain insights of the viral structure, the clinical manifestations, and the immune responses caused by SARS‐CoV‐2. These movements can promote rapid development of therapeutic drugs, antibodies, and vaccines for this novel virus.
【저자키워드】 Clinical symptoms, SARS‐CoV‐2, immune responses, Biology, Therapeutic treatment, 【초록키워드】 Treatment, public health, immunology, antibodies, Vaccine, Cytokine storm, coronavirus, immune response, Pneumonia, Diagnosis, drugs, Respiratory illness, virus, acute lung injury, Novel coronavirus, SARS‐CoV‐2, global pandemic, clinical manifestations, outbreak, therapeutic, RaTG13, Cluster, acute respiratory distress, acute respiratory syndrome, severe respiratory disease, syndrome, SARS‐CoV‐2 infection, previous study, sequence identity, shown, caused, suggested, promote, induce, cause, dysregulated, 【제목키워드】 SARS‐CoV‐2, Continuous,