We sequenced the genomes of 14 sequential Salmonella enterica serovar Typhimurium isolates obtained over a five year period from a patient with persistent Salmonella bacteriuria. The isolates formed five distinct lineages; two of which co-existed over four years. We inferred that the observed within-patient variation resulted from mutation events.
All Keywords
【저자키워드】 Genome sequencing, Single nucleotide polymorphisms (SNPs), bacteriuria, chronic carrier, Salmonella enterica serovar Typhimurium (S. Typhimurium), Serial isolates,
【저자키워드】 Genome sequencing, Single nucleotide polymorphisms (SNPs), bacteriuria, chronic carrier, Salmonella enterica serovar Typhimurium (S. Typhimurium), Serial isolates,