The explanation of the potential interaction between the influenza vaccine and SARS-CoV-2 infection is urgently needed in the public health. The objective of the study is to compare the occurrence of positive SARS-CoV-2 IgG and IgM tests in subjects with and without recent (last year) seasonal influenza vaccinations. In a cross-sectional study located in three large towns of Silesian Voivodeship (Poland), we studied 5479 subjects in which 1253 (22.9%) had a positive anti-SARS-CoV-2 IgG test and 400 (7.3%) had a positive anti-SARS-CoV-2 IgM test. Seasonal influenza vaccination remains an independent factor protecting against positive IgG tests (OR = 0.68; 0.55–0.83). The effect is not apparent with IgM antibodies. The obtained results confirmed that the serological status of SARS-CoV-2 infection depends on vaccination against seasonal influenza.
【저자키워드】 cross-sectional study, influenza vaccination, seropositivity of COVID-19, 【초록키워드】 public health, Vaccine, vaccination, Influenza, cross-sectional, SARS-COV-2 infection, Poland, IgM antibodies, anti-SARS-CoV-2 IgG, serological, SARS-CoV-2 IgG, anti-SARS-CoV-2 IgM, Interaction, Vaccinations, Seasonal influenza, IgG test, subject, IgM test, positive, seasonal, independent, Occurrence, 【제목키워드】 IgM, Test, Poland, Population, Region, SARS-CoV-2 IgG,