Statement of Significance: COVID-19 reminds us of the critical importance of pandemic preparedness, requiring sophisticated approaches to facilitate and accelerate reagent development against emerging threats. We described an integrated pipeline approach to rapidly craft in parallel ADDomer-based nanoparticles for vaccination and for passive immunization, applicable to many infectious diseases.
All Keywords
【저자키워드】 pandemic preparedness, respiratory viral diseases, Synthetic vaccine, ADDomer, electron cryo-microscopy (cryo-EM), Gigabody superbinder, in vitro selection (Ribosome Display), protein nanoparticle design,
【저자키워드】 pandemic preparedness, respiratory viral diseases, Synthetic vaccine, ADDomer, electron cryo-microscopy (cryo-EM), Gigabody superbinder, in vitro selection (Ribosome Display), protein nanoparticle design,