The ability of BCG vaccination to prevent pulmonary tuberculosis could be improved by targeting mucosal immunity within the lung. Here the authors compare latent Mtb-infected donors with intradermal or oral BCG vaccine recipients to show distinct systemic and pulmonary immune responses are induced by differing routes of natural infection or vaccination.
All Keywords
【저자키워드】 Translational research, Predictive markers, Live attenuated vaccines, Gene regulation in immune cells, CD4-positive T cells,
【저자키워드】 Translational research, Predictive markers, Live attenuated vaccines, Gene regulation in immune cells, CD4-positive T cells,