Here the authors demonstrate that the SARS-CoV-2 main protease (Mpro) is subject to redox regulation in vitro, reversibly switching between the enzymatically active dimer and the functionally dormant monomer through redox modifications of cysteine residues.
All Keywords
【저자키워드】 X-ray crystallography, Enzyme mechanisms, chemical modification, Proteases,
【저자키워드】 X-ray crystallography, Enzyme mechanisms, chemical modification, Proteases,