Systematic understanding of CRISPR enzyme RNA binding specificity and cleavage is lacking. Here the authors report RNA chip-hybridised association-mapping platform (RNA-CHAMP), a workflow that repurposes next generation DNA sequencing chips to measure the binding affinity for RNA targets.
All Keywords
【저자키워드】 Enzyme mechanisms, RNA, CRISPR-Cas systems, Biophysical methods,
【저자키워드】 Enzyme mechanisms, RNA, CRISPR-Cas systems, Biophysical methods,