Simple Summary Malignant neoplasms of female genital organs cause a large number of deaths worldwide. The death rates from these diseases are higher in Poland than in many European Union countries. Educational programmes, screening tests and HPV vaccination are being introduced in Poland to counteract these differences. Monitoring the effectiveness of the planned actions should be accompanied by the implementation of studies on changes in mortality trends. In our study, we analysed all deaths of female residents of Poland between 2000 and 2021 included in the Statistics Poland database. We determined trends in changes in mortality due to malignant neoplasms of female genital organs in total and separately for individual cancers from this group. We also analysed educational and urbanisation differences in mortality due to this group of tumours. The obtained results should be useful in designing adequate preventive actions. Abstract The aim of this study is to assess mortality trends due to malignant neoplasms of female genital organs (MNFGOs) in Poland between 2000 and 2021. For the purpose of the study, the authors used data on all deaths of Polish female inhabitants due to MNFGO between 2000 and 2021, obtained from the Statistics Poland database. The standardised death rates (SDR), potential years of life lost (PYLL), annual percentage change (APC) and average annual percentage change (AAPC) were calculated. Between the years 2000 and 2021, 138,000 women died due to MNFGOs in Poland. Of this number, 54,975 (39.8%) deaths were caused by ovarian cancer, 37,487 (27.2%) by cervix uteri cancer, and 26,231 (19.0%) by corpus uteri cancer. A decrease in mortality due to cervix uteri cancer (APC = −2.4%, p < 0.05) was the most favourable change that occurred in the period 2000–2021, while the least favourable change was an increase in mortality due to corpus uteri cancer for the period 2005–2019 (APC = 5.0%, p < 0.05). SDRs due to ovarian cancer showed a decreasing trend between 2007 and 2021 (APC = −0.5%, p < 0.05). The standardised PYLL index due to cervical cancer was 167.7 per 100,000 women in 2000 and decreased to 75.0 in 2021 (AAPC = −3.7, p < 0.05). The number of lost years of life due to ovarian cancer decreased from 143.8 in 2000 to 109.5 in 2021 (AAPC = −1.3, p < 0.05). High values of death rates due to MNFGO in Poland, compared to other European countries, show that there is a need to promote preventive programmes and continue to monitor changes in mortality.
【저자키워드】 Mortality, Epidemiology, Cancer, Poland, trends, female genital organs,