This prospective observational study evaluated the safety and feasibility of a low threshold testing process in a Triage and Test Center (TTC) during the early course of the coronavirus disease 19 (COVID-19) pandemic. In addition, we aimed to identify clinical predictors for a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) swab result. Patients underwent informal triage, standardized history taking, and physician evaluation, only where indicated. Patients were observed for 30 days. Safety was the primary outcome and was defined as a COVID-19-related 30 day re-presentation rate <5% and mortality rate <1% in patients presenting to the TTC. Feasibility was defined as an overruling of informal triage <5%. Among 4815 presentations, 572 (11.9%) were tested positive for SARS-CoV-2, and 4774 were discharged. Mortality at 30-days was 0.04% (2 patients, one of which related to COVID-19). Fever (OR 2.03 [95% CI 1.70;2.42]), myalgia (OR 1.94 [1.63;2.31]), chills (OR 1.77 [1.44;2.16]), headache (OR 1.61 [1.34;1.94]), cough (OR 1.50 [1.24;1.83]), weakness (OR 1.46 [1.21;1.76]), and confusion (OR 1.39 [1.06;1.80]) were associated with test positivity. Re-presentation rate was 8% overall and 1.4% in COVID-19 related re-presentation (69 of 4774). The overruling rate of informal triage was 1.5%. According to our study, a low-threshold testing process in a TTC appeared to be safe (low re-presentation and low mortality) and is feasible (low overruling of informal triage). A COVID-19 diagnosis based on clinical parameters only does not appear possible.
【저자키워드】 COVID-19, SARS-CoV-2, Symptoms, Resource allocation, disposition, Triage and Test Center, drive-thru testing, 【초록키워드】 coronavirus disease, coronavirus, pandemic, Mortality, Safety, feasibility, prospective observational study, Test, Triage, cough, headache, Patient, COVID-19 diagnosis, Swab, mortality rate, predictor, patients, myalgia, Safe, Confusion, acute respiratory syndrome, Primary outcome, center, weakness, positive, chill, clinical parameter, Course, defined, tested, identify, indicated, addition, evaluated, feasible, discharged, presenting, threshold testing, 【제목키워드】 Safety, Test, Triage, Testing,