We conducted a challenge/rechallenge trial in which 3 alpacas were infected with Middle East respiratory syndrome coronavirus. The alpacas shed virus at challenge but were refractory to further shedding at rechallenge on day 21. The trial indicates that alpacas may be suitable models for infection and shedding dynamics of this virus.
All Keywords
【저자키워드】 viruses, zoonoses, Vaccine, coronavirus, SARS, Infection, MERS-CoV, Severe acute respiratory syndrome, shedding, alpaca, Middle East respiratory syndrome, Camel, experimental animal model, rechallenge, 【초록키워드】 Trial, virus, Middle East, respiratory syndrome coronavirus, were infected, conducted, indicate, 【제목키워드】 response, respiratory, Middle East,
【저자키워드】 viruses, zoonoses, Vaccine, coronavirus, SARS, Infection, MERS-CoV, Severe acute respiratory syndrome, shedding, alpaca, Middle East respiratory syndrome, Camel, experimental animal model, rechallenge, 【초록키워드】 Trial, virus, Middle East, respiratory syndrome coronavirus, were infected, conducted, indicate, 【제목키워드】 response, respiratory, Middle East,