Background: Germany reported sufficient intensive care unit (ICU) resources throughout the first wave of coronavirus disease 2019 (COVID-19). The treatment of critically ill COVID-19 patients without rationing may improve the outcome. We therefore analyzed ICU resources allocated to COVID-19 patients with respiratory failure and their outcomes. Methods: Retrospectively, we enrolled severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR)-positive patients with respiratory failure from 03/08/2020 to 04/08/2020 and followed until 05/28/2020 in the university hospital of Freiburg, Germany. Results: In the defined interval, 34 COVID-19 patients were admitted to the ICU with median age of 67±13 (31-86) years. Six of 34 (17.6%) were female. All patients suffered from moderate or severe acute respiratory distress syndrome (ARDS), 91.2% of the patients were intubated and 23.5% required extracorporeal membrane oxygenation (ECMO). Proning was performed in 67.6%, renal replacement therapy (RRT) was required in 35.3%. Ninety-six percent required more than 20 nursing hours per day. Mean ICU stay was 21±19 (1-81) days. Sixty-day survival of critically ill COVID-19 patients was 50.0% (17/34). Causes of death were multi-organ failure (52.9%), refractory ARDS (17.6%) and intracerebral hemorrhage (17.6%). Conclusions: Treatment of critically ill COVID-19 patients is protracted and resource-intense. In a context without resources shortage, 50% of COVID-19 with respiratory failure survived up to 60 days.
【저자키워드】 COVID-19, ARDS, 60-day survival, ICU resources, 【초록키워드】 Treatment, coronavirus disease, SARS-CoV-2, coronavirus, Respiratory failure, intensive care, outcome, ICU, outcomes, extracorporeal membrane oxygenation, survival, Critically ill, Germany, female, Patient, death, ECMO, resource, First wave, moderate, acute respiratory distress, Intracerebral hemorrhage, renal replacement therapy, COVID-19 patient, RRT, acute respiratory syndrome, Intubated, median age, university hospital, syndrome, multi-organ failure, polymerase chain, IMPROVE, enrolled, defined, analyzed, reported, the patient, required, was performed, per day, suffered, cause, survived,