In a preliminary clinical study, we observed that the combination of hydroxychloroquine and azithromycin was effective against SARS-CoV-2 by shortening the duration of viral load in Covid-19 patients. It is of paramount importance to define when a treated patient can be considered as no longer contagious. Correlation between successful isolation of virus in cell culture and Ct value of quantitative RT-PCR targeting E gene suggests that patients with Ct above 33–34 using our RT-PCR system are not contagious and thus can be discharged from hospital care or strict confinement for non-hospitalized patients.
All Keywords
【저자키워드】 COVID-19, SARS-CoV2, RT-PCR, Viral load, correlation, co-culture, 【초록키워드】 SARS-CoV-2, Hydroxychloroquine, hospital, virus, Cell culture, Patient, Isolation, Quantitative, Care, patients, clinical study, Combination, E gene, contagious, effective, treated, to define, discharged, 【제목키워드】 Infectious disease, discharge, RNA, management, Cell culture, SARS-CoV-2 patient,
【저자키워드】 COVID-19, SARS-CoV2, RT-PCR, Viral load, correlation, co-culture, 【초록키워드】 SARS-CoV-2, Hydroxychloroquine, hospital, virus, Cell culture, Patient, Isolation, Quantitative, Care, patients, clinical study, Combination, E gene, contagious, effective, treated, to define, discharged, 【제목키워드】 Infectious disease, discharge, RNA, management, Cell culture, SARS-CoV-2 patient,