Abstract Background Coronavirus disease 2019 (COVID‐19) pandemic imposes serious problems to health systems around the world and its rapid expansion makes it difficult to serve patients with certain health conditions such as cancer patients which might be at high risk for mortality if they are infected by the severe acute respiratory syndrome coronavirus 2. Aim To compare the outcomes of cancer patients admitted due to COVID‐19 and compare them with data of COVID‐19 infected patients without a history of cancer. Methods In this case‐controlled study, 93 healthy people and 92 patients with malignancy admitted for COVID‐19 were enrolled. The clinical features and laboratory indicators were assessed at the presentation and both groups were followed‐up for treatment options and outcomes prospectively and compared at the level of P ≤ .05. Results COVID‐19 related mortality rate in malignant patients was significantly higher than patients without malignancy (41.3% vs 17.2%, P = .0001). The risk of death increased significantly in patients with malignancy (OR = 8.4, P = .007) and mechanical ventilation (OR = 3.3, P = .034) independent of other variables. Fever (64.5% vs 43.5%, P = .004), chill (35.5% vs 14.1%, P = .001), malaise (49.5% and 30.4%, P = .008), dry cough (51.6% vs 26.1%, P = .0001), and vomiting (17.2% vs 5.4%, P = .012) were reported significantly lower in cancer patients. Conclusion The results suggest that cancer patients who were infected by COVID‐19 may present with atypical symptoms are at higher risk of mortality independent of the demographic data, comorbidities, and treatments.
【저자키워드】 COVID‐19, Mortality, malignancy, 【초록키워드】 Treatment, Coronavirus disease 2019, coronavirus, pandemic, mechanical ventilation, Cancer, Comorbidities, outcome, Laboratory, COVID‐19, Patient, Cancer patients, mortality rate, health system, clinical feature, high risk, cancer patient, risk of death, acute respiratory syndrome, higher risk, dry cough, demographic data, problem, malaise, rapid expansion, vomiting, health condition, significantly lower, independent, other variables, Result, enrolled, were infected, significantly, healthy, reported, infected patient, significantly higher, atypical symptom, both group, were assessed, 【제목키워드】 COVID, Iran, mortality rate, cancer patient, atypical symptom,