Uncertainty remains about how long the protective immune responses against severe acute respiratory syndrome coronavirus 2 persists, and suspected reinfection in recovered patients has been reported. We describe a case of reinfection from distinct virus lineages in Brazil harboring the E484K mutation, a variant associated with escape from neutralizing antibodies.
All Keywords
【저자키워드】 COVID-19, coronavirus disease, severe acute respiratory syndrome coronavirus 2, viruses, respiratory infections, zoonoses, Brazil, SARS-CoV-2, Genomic surveillance, Reinfection, E484K spike mutation, 【초록키워드】 Brazil, coronavirus, Neutralizing antibodies, variant, severe acute respiratory syndrome Coronavirus, virus, immune responses, Lineage, escape, E484K mutation, recovered patients, respiratory, Uncertainty, acute respiratory syndrome, acute respiratory syndrome coronavirus, acute respiratory syndrome coronavirus 2, protective immune response, recovered patient, reported, persists, 【제목키워드】 spike, E484K, evidence of, Involving,
【저자키워드】 COVID-19, coronavirus disease, severe acute respiratory syndrome coronavirus 2, viruses, respiratory infections, zoonoses, Brazil, SARS-CoV-2, Genomic surveillance, Reinfection, E484K spike mutation, 【초록키워드】 Brazil, coronavirus, Neutralizing antibodies, variant, severe acute respiratory syndrome Coronavirus, virus, immune responses, Lineage, escape, E484K mutation, recovered patients, respiratory, Uncertainty, acute respiratory syndrome, acute respiratory syndrome coronavirus, acute respiratory syndrome coronavirus 2, protective immune response, recovered patient, reported, persists, 【제목키워드】 spike, E484K, evidence of, Involving,
중증급성호흡기증후군 코로나바이러스 2에 대한 보호 면역 반응이 얼마나 오래 지속되는지에 대한 불확실성이 남아 있으며 회복된 환자에서 재감염이 의심되는 것으로 보고되었습니다. 우리는 중화 항체로부터의 탈출과 관련된 변형인 E484K 돌연변이를 품고 있는 브라질의 별개의 바이러스 계통에서 재감염된 경우를 설명합니다.