Monkeypox Virus Detection Using Pre-trained Deep Learning-based ApproachesArticle Published on 2022-10-062022-11-15 Journal: Journal of medical systems [Category] Fulltext, 원숭이두창, 치료기술, [키워드] addition approach average classification community transmission COVID-19 COVID-19 virus dataset deep deep learning detect detection early stage experiment fine-tune Health help identify IMPROVE Infection majority Monkeypox pandemic Practitioner SARS-CoV2 virus virus detection widespread [DOI] 10.1007/s10916-022-01868-2 PMC 바로가기
COVID-19-related health outcomes in people with primary immunodeficiency: A systematic reviewReview article Published on 2022-10-012022-10-05 Journal: Clinical immunology (Orlando, Fla.) [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] addition approach article association B-cell calculated candidate COVID-19 COVID-19 vaccination duplicates Effectiveness eligible English Factors Fatality rate first positive General population Genetic variant Health Hospitalization illnesses immune response immune system immunodeficiency implication inborn errors of immunity include indicated infections isolate likelihood morbidity and mortality negative test outcome oxygen supplementation pathway performed positive Primary Immunodeficiency Prolonged infection Prophylaxis public health reported response SARS-CoV-2 SARS-CoV-2 test SARS-CoV2 Sequencing Symptom systematic review tested Transmission Vaccinations Vaccine variants whole genome X-linked agammaglobulinemia XLA [DOI] 10.1016/j.clim.2022.109097 [Article Type] Review article
SARS-CoV-2 infection impacts carbon metabolism and depends on glutamine for replication in Syrian hamster astrocytesArticle Published on 2022-10-012022-11-16 Journal: Journal of neurochemistry [Category] COVID19(2023년), SARS, 치료기술, [키워드] Alpha Alter Astrocyte astrocytes blockade Brain carbon metabolism cause change Cognitive impairment Confusion COVID-19 death evaluated Evidence evidenced Glucose Glutamine Glycolysis hamsters Hyperactivation Immunopathogenesis Impact in vitro in vivo Inflammatory response intranasally ketoglutarate Lung disease memory metabolomics neurological Neurological diseases neurological impairment Neuropathology neurotransmitter olfactory Protein proteomics pyruvate reduction Replication SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 synaptic Transmission viral replication [DOI] 10.1111/jnc.15679 PMC 바로가기
MOG encephalomyelitis after vaccination against severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2): case report and comprehensive review of the literatureArticle Published on 2022-10-012022-11-15 Journal: Journal of Neurology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] acute respiratory syndrome Adults affected analysed antibody AstraZeneca attack available data AZD1222 blindness BNT162b2 booster vaccination Brain Brainstem Brainstem encephalitis Case report cerebrospinal fluid ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1-S CNS complete recovery coronavirus Coronavirus disease 2019 Coronavirus disease 2019 (COVID-2019) COVID-19 CSF detectable disease dysfunction Encephalitis epidemiological Escalation exceeded female first dose functional glycoprotein IgG1 immunization Immunoglobulin Immunotherapy laboratory feature Longitudinally extensive transverse myelitis (LETM) majority male median median age median interval MOG MOG antibodies (MOG-IgG) mRNA vaccine mRNA-1273 much lower Myelin Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) Myelin oligodendrocyte glycoprotein antibody-associated encephalomyelitis (MOG-EM) Myelitis Neuromyelitis Optica Neuromyelitis optica spectrum disorders occur occurred Optic Optic neuritis Oxford paraplegia Patient patients patients with SARS-CoV-2 Pfizer phenotype plasma Postinfectious Postvaccinal predominant radiological remained required residual symptom SARS-CoV2 serum Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) severity steroid treatment therapy Treatment Treatment outcome vaccination Vaccine WCC white cell [DOI] 10.1007/s00415-022-11194-9 PMC 바로가기
Clinical course of Coronavirus Disease-19 in patients with haematological malignancies is characterized by a longer time to respiratory deterioration compared to non-haematological ones: results from a case-control studyArticle Published on 2022-10-012023-07-09 Journal: Infection [Category] COVID19(2023년), [키워드] COVID-19 haematological malignancy Multiple myeloma Non-Hodgkin Lymphoma SARS-CoV2 [DOI] 10.1007/s15010-022-01869-w PMC 바로가기
Histologic, viral, and molecular correlates of heart disease in fatal COVID-19Research article Published on 2022-10-012022-10-05 Journal: Annals of diagnostic pathology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] ACE2 expression activated arrhythmia Arrhythmias cardiac connexin 43 Control COVID-19 disease dysfunction edema endocytosed Endothelial cell evidenced experiment expression fatal COVID-19 greater heart heart tissue histologic host response IL6 immunohistochemistry In situ hybridization induce interstitial Macrophage manifestation Migration molecular multifocal myocarditis Myocardium Myocyte nucleocapsid protein obesity perivascular predominant Protein Proteins quantified risk RNA SARS-CoV-2 spike protein SARS-CoV2 severe COVID-19 sodium Spike protein the spike protein tissue TNFα Type II Diabetes unique Viral protein viral spike protein would increase [DOI] 10.1016/j.anndiagpath.2022.151983 [Article Type] Research article
Comparison of the characteristics, morbidity and mortality of COVID-19 between first and second/third wave in a hospital setting in Lombardy: a retrospective cohort studyComparative Study Published on 2022-10-012023-07-09 Journal: Internal and Emergency Medicine [Category] COVID19(2023년), [키워드] COVID-19 Mortality Prognostic factors SARS-CoV2 Waves [DOI] 10.1007/s11739-022-03034-5 PMC 바로가기 [Article Type] Comparative Study
Innate Immune Response and Inflammasome Activation During SARS-CoV-2 InfectionArticle Published on 2022-10-012022-11-15 Journal: Inflammation [Category] COVID19(2023년), SARS, 변종, 진단, 치료제, [키워드] Activation Antiviral characterized Clinical outcome COVID-19 COVID-19 outbreak Defense develop drug Effect evade flexibility Genome human pathogen IL-18 IL-1β IL-6 immune immune response immunopathology implicated IMPROVE Infection infective Inflammasome inflammasome pathway inflammatory disease inhibiting Innate innate immune response innate immune system interferon Intervention mutant strain NLRP3 novel coronavirus SARS-CoV-2 pandemic pathology Predictive preventive measure pro-inflammatory cytokine promote protective role public health receptor Replication response responsible RNA virus SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 shown the interferon treating COVID-19 Trigger urgent investigation Vaccine vaccine candidate vaccine candidates vaccine for COVID-19 viral disease viral evolution virus viruses [DOI] 10.1007/s10753-022-01651-y PMC 바로가기
Early report on the severity of COVID-19 in hematologic patients infected with the SARS-CoV2 omicron variantArticle Published on 2022-10-012022-11-16 Journal: European journal of haematology [Category] COVID19(2023년), SARS, 변종, [키워드] Ageusia Asymptomatic cause caused condition cough COVID-19 Critical death described disease disease severity fatigue Fever hematologic Hematologic diseases heterogeneous high risk host immunity ICU admission immunodeficiency Infection investigated laboratory parameter less majority Mild symptom morbidity and mortality Mortality nucleic acid amplification observation period occurred omicron Omicron variant Oxygen therapy Patient patient cohort patients remained reported reported symptom required SARS-CoV2 SARS-CoV2 infection severity severity of COVID-19 symptoms of COVID-19 variants viral pathogenicity [DOI] 10.1111/ejh.13818 PMC 바로가기
In silico drug designing for COVID-19: an approach of high-throughput virtual screening, molecular, and essential dynamics simulationsArticle Published on 2022-10-012023-07-06 Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), [키워드] docking essential dynamics simulation MD simulation MPro SARS-CoV2 Virtual screening [DOI] 10.1080/07391102.2021.1897681