Lymphocyte Changes in Severe COVID-19: Delayed Over-Activation of STING?
심각한 COVID-19의 림프구 변화: STING의 지연된 과활성화?
Review
[키워드] ACE2
activated
Activation
acute respiratory syndrome
affected
antigen presenting cell
antigen presenting cells
Aspirin
autophagy
B cell
B cell response
B cells
CD147
CD26
CD4+
CD8+
CD8+ T cell
cGAMP
cGAS
change
contribute
coronavirus
coronavirus disease
Coronavirus disease 2019
COVID-19
cyclic
cytokine
cytokine secretion
damages
Delayed
dinucleotide
DNA
DNA damage
early stages
Express
expressed
functional
Gain of function
Genes
Host
Human
IL-6
immune cells
induce
infancy
Infection
inhibit
inhibitor
interferon
IRF3
Last
less
lymphocyte
Lymphocytes
lymphopenia
main receptor
microbial
NF-κB
pathway
Pneumonitis
Recognition
respiratory
responsiveness
SARS-CoV-2
severe coronavirus disease
severe COVID-19
severe COVID-19 patient
severe COVID-19 patients
similarity
SLC19A1
small molecule
Small molecules
stimulator
STING
T and B cell responses
T cell
T cells
TBK1
TCR
Th2
transfer
triggered
Vasculopathy
[DOI] 10.3389/fimmu.2020.607069 PMC 바로가기 [Article Type] Review
[DOI] 10.3389/fimmu.2020.607069 PMC 바로가기 [Article Type] Review