cytoplasm
[용어속성] Cell
SARS-Coronavirus Replication Is Supported by a Reticulovesicular Network of Modified Endoplasmic Reticulum
Research Article
[키워드] acute respiratory syndrome
alteration
Analysis
Antiviral
applied
arising
Author
biochemical
characterized
complex
connection
coronavirus
cytoplasm
cytosol
Defense
defined
dissect
double-stranded RNA
driven by
early stage
electron tomography
Endoplasmic reticulum
endoplasmic reticulum membrane
enzyme
ER membrane
host cell
host cell membrane
host cell membranes
host cells
human pathogen
implicated
in viral
induce
Infected
infected cell
interior
invagination
mechanism
mechanisms
membrane
membrane-bound
membranes
Microscopy
network
question
raise
replicate
Replication
replication complex
replicative protein
reported
Reticulum
reveal
RNA
RNA genome
RNA synthesis
RNA virus
RNA viruses
SARS-coronavirus
SARS-CoV
Structure
subunits
Support
thought
tomography
ultrastructure
unique
Vesicle
vesicles
viral replication
viral RNA synthesis
virus
Virus-host interactions
Web
[DOI] 10.1371/journal.pbio.0060226 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pbio.0060226 PMC 바로가기 [Article Type] Research Article
SARS-Coronavirus Replication/Transcription Complexes Are Membrane-Protected and Need a Host Factor for Activity In Vitro
Research Article
[키워드] activity
acute respiratory syndrome
addition
Author
cause
centrifugation
characteristic
complex
complexes
connection
Critical
cytoplasm
cytoplasmic
Degradation
dependent on
develop
digestion
dissect
eight
enzyme
Enzymes
Factor
fraction
functional
genomic RNA
Host
host cell membranes
host cells
in vitro
in vitro activity
Infected
infected cell
life-threatening
membrane
membrane structure
membrane structures
membranes
non-structural protein
NSP
Nsps
polyproteins
precursor
produced
protease
PROTECT
protein synthesis
released
remained
replicate
Replication
required
RNA
RNA synthesis
robust
RTC
SARS-coronavirus
SARS-CoV
SARS-CoV-infected cells
Structure
subgenomic mRNA
subgenomic mRNA synthesis
subunit
susceptible
Transcription
Treatment
viral genome replication
Viral RNA
viral RNA synthesis
virus-induced membrane structure
virus-induced membrane structures
[DOI] 10.1371/journal.ppat.1000054 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.ppat.1000054 PMC 바로가기 [Article Type] Research Article
Ultrastructural Characterization of SARS Coronavirus
Research
[키워드] acute respiratory syndrome
addition
assays
bronchiolar
characterization
composed
coronavirus
coronavirus-infected cell
Critical
culture cells
cytoplasm
death
described
disease transmission
electron
electron microscopy
Emerging infectious diseases
feature
granular
immunogold techniques
In situ
In situ hybridization
Infected
Infection
Laboratory
nucleocapsid
outbreak
Particle
positive
replication complex
RNA
SARS patient
SARS virus
severe
Severe acute respiratory syndrome
severe pneumonia
shown
specimen
Structure
subsequent
ultrastructure
vesicles
Viral protein
virus isolate
[DOI] 10.3201/eid1002.030913 PMC 바로가기 [Article Type] Research
[DOI] 10.3201/eid1002.030913 PMC 바로가기 [Article Type] Research