Glycosylation of Receptor Binding Domain of SARS-CoV-2 S-Protein Influences on Binding to Immobilized DNA AptamersArticle Published on 2022-01-052022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] affected amino acid substitution aptamer Aptamers binding Biolayer interferometry cell line Chinese hamster coronavirus development dissociation constants DNA Effects Efficacy element expressed expression glycosylation glycosylation patterns influence inhibitor new virus Pichia pastoris RBD Receptor binding domain Receptor-binding domain recognizing S-protein SARS-CoV-2 sensor surface spike glycoprotein tested the RBD the RBD protein therapy variant viral infection viral strain virion [DOI] 10.3390/ijms23010557 PMC 바로가기 [Article Type] Article
Nimble Approach: fast, adapting, calculating and ethically mindful approach to managing colorectal cancer screening programmes during a pandemicNimble Approach: 대유행 기간 동안 대장암 검진 프로그램을 관리하기 위한 빠르고 적응력 있고 계산적이며 윤리적인 접근 방식Article Published on 2022-01-012022-09-11 Journal: BMJ open gastroenterology [Category] SARS, 치료기술, [키워드] adaptive Analysis approach Australasia Calculating Cancer screening case study Colorectal cancer colorectal cancer screening conducted COVID-19 COVID-19 pandemic crisis Data analysis Decision-making element elements Europe greater grounded theory Health initial International North America outcome pandemic Pandemics participant positioned provide researcher researchers respond responses Screening screening process Seven Support [DOI] 10.1136/bmjgast-2021-000826 PMC 바로가기 [Article Type] Article
High throughput molecularly imprinted polymers based electrochemical nanosensors for point-of-care diagnostics of COVID-19Short communication Published on 2022-01-012022-10-05 Journal: Materials Letters [Category] 진단, [키워드] Biorecognition elements costly COVID-19 COVID-19 pandemic diagnostic diagnostics early diagnosis electrochemical sensors element elements fabrication Infectious disease Molecularly imprinted polymer offer point-of-care Polymer SARS-CoV-2 specificity time-consuming [DOI] 10.1016/j.matlet.2021.130898 [Article Type] Short communication
Community-engaged Processes for Restarting Federally Funded Research in a Community-based Organization during the Coronavirus Disease 2019 PandemicRandomized Controlled Trial Published on 2022-01-012022-10-05 Journal: Progress in community health partnerships : research, education, and action [Category] 임상, [키워드] activity AIDS approach Community conducted coronavirus disease COVID-19 COVID-19 pandemic Critical element Intervention management organization organized outreach pandemic partner people with HIV Pittsburgh provided Public Randomized controlled trial Research Research protocol Rhode School university [DOI] 10.1353/cpr.2022.0044 PMC 바로가기 [Article Type] Randomized Controlled Trial
miRNAs, from Evolutionary Junk to Possible Prognostic Markers and Therapeutic Targets in COVID-19miRNA, 진화 적 쓰레기에서 가능한 예후 마커 및 covid-19의 치료 표적까지Review Published on 2021-12-272022-09-10 Journal: Viruses [Category] SARS, 치료제, [키워드] addition among others Antiviral treatment cellular Complication complications COVID-19 COVID-19 pandemic COVID-19 patients cytokine Cytokine storm element Exacerbation Genes Genetic genetic regulation high risk highlight Host identify increased expression inflammatory process intensive care intensive care unit Interaction microRNA miR-122 miR-155 miR-200 miR-21 miRNA miRNAs molecular Mortality neuronal pathophysiology Patient predictor Prognosis prognostic public health Regulation renal required risk SARS-CoV-2 target the disease therapeutic therapeutic targets Viral virus [DOI] 10.3390/v14010041 PMC 바로가기 [Article Type] Review
Clinical Practice Guideline: Recommendations on the In-hospital Treatment of Patients with COVID-19임상 진료 지침: COVID-19 환자의 병원 내 치료에 대한 권장 사항Article Published on 2021-12-272022-09-12 Journal: Deutsches Ärzteblatt international [Category] SARS, 진단, [키워드] administration anticoagulation benefit Care clinical Clinical practice Combination Consensus Corticosteroids COVID-19 COVID-19 patient CPAP D-dimer level demonstrated element elevated example group high-flow oxygen therapy hospital hypoxemic implementation IMPROVE inhibitors intensive care invasive ventilation Jak jak inhibitors low-flow oxygen Medline database monoclonal antibodies monoclonal antibody Mortality noninvasive oxygen Oxygen requirement Patient patients patients with COVID-19 positive airway pressure Practice prone positioning recommendations reduction retrieved risk severe COVID-19 disease systemic corticosteroids the disease therapeutic anticoagulation therapy Thromboembolism Tocilizumab treated Treatment Trial Ventilation with COVID-19 [DOI] 10.3238/arztebl.m2021.0374 PMC 바로가기 [Article Type] Article
SARS-CoV-2 infection mediates differential expression of human endogenous retroviruses and long interspersed nuclear elementsSARS-CoV-2 감염은 인간 내인성 레트로바이러스와 긴 산재된 핵 요소의 차등 발현을 매개합니다Research Article Published on 2021-12-222022-09-10 Journal: JCI Insight [Category] SARS, 유전자 메커니즘, [키워드] activities activity binding site bioinformatics Bronchoalveolar lavage fluid Cell cell line cell lines cellular response Coronaviridae coronavirus COVID-19 differential expression differentially expressed distinctive features downregulation downstream Effect element expression feature host gene host gene expression host response human endogenous retrovirus human parainfluenza virus IAV immune response immune responses infection with SARS-CoV-2 Infectious disease Influenza influenza A influenza A virus innate immune Innate immunity investigated involved MERS MERS-CoV Middle East Middle East respiratory syndrome Coronavirus modulate modulating nuclear overexpression Patient patients with COVID-19 PBMCs promote Protein respiratory respiratory syncytial virus respiratory syndrome coronavirus RNA-seq data RSV SARS-CoV-2 SARS-COV-2 infection severity of COVID-19 subset Telescope transcription factor transcription factors Transcriptome transcripts unique upregulation Viral virus viruses [DOI] 10.1172/jci.insight.147170 PMC 바로가기 [Article Type] Research Article
The Spread of COVID-19 Crisis Communication by German Public Authorities and Experts on Twitter: Quantitative Content Analysis트위터에서 독일 공공 기관 및 전문가의 COVID-19 위기 커뮤니케이션 확산: 정량적 콘텐츠 분석Original Paper Published on 2021-12-222022-09-10 Journal: JMIR Public Health and Surveillance [Category] SARS, 치료기술, [키워드] Analysis appear association authorities authority carried communication components Consequences content content analysis Coverage COVID-19 COVID-19 case COVID-19 cases COVID-19 crisis COVID-19 pandemic crisis crisis communication Descriptive analysis Descriptive statistics detect development element evaluate example expert experts Germany health authorities incidence rate increasingly information media Multivariate analysis negative negative binomial regression objective pandemic performed positive Public public health authorities Quantitative reached Recognition reduce Regression representing required responsible Result significantly similarities similarity social media Spread Twitter [DOI] 10.2196/31834 PMC 바로가기 [Article Type] Original Paper
Severe Acute Respiratory Syndrome Coronavirus 2 Antibodies Among Healthcare Workers After Vaccine Administration in an Intensive Care UnitPathology Published on 2021-12-212022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome administration antibody China coronavirus coronavirus 2 coronavirus disease COVID-19 COVID-19 vaccine declined decrease determine element greater group had more HCW HCWs health institution healthcare worker Healthcare workers IgG IgG antibodies IgG antibody Immunoglobulin Immunoglobulin G in both group Infection intensive care intensive care unit knowledge less manifested professional Prospective Study Public health interventions respiratory SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody response second dose spread of COVID-19 Symptom Symptoms the vaccine Vaccine vaccine administration worker [DOI] 10.7759/cureus.20579 PMC 바로가기 [Article Type] Pathology
Modeling SARS-CoV-2 Infection in Mice Using Lentiviral hACE2 Vectors Infers Two Modes of Immune Responses to SARS-CoV-2 InfectionLentiviral hACE2 벡터를 사용한 쥐의 SARS-CoV-2 감염 모델링은 SARS-CoV-2 감염에 대한 두 가지 면역 반응 모드를 추론합니다Article Published on 2021-12-212022-09-12 Journal: Viruses [Category] SARS, 진단, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus Analysis angiotensin antiviral drugs applied caused contribute coronavirus COVID-19 effectors element enzyme expression Gene expression analysis generate global pandemic hACE2 human Angiotensin-converting enzyme Human angiotensin-converting enzyme 2 human cell human cells IFNAR1 immune immune response immune responses immunogenic in vivo infected cell Infection interferon interferon receptor knock-out lack Lentiviral vector lentiviral vectors lentivirus lung Lung disease mice Mild mode modeling mouse model pathology productive viral replication receptor response SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection SARS-CoV-2 particle SARS-CoV-2 particles SARS-CoV-2 replication severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Signaling stimulate Strains supported susceptible transgenic mice triggered Type I IFN Vaccine development vector virus wild-type [DOI] 10.3390/v14010011 PMC 바로가기 [Article Type] Article