Protective action of natural and induced immunization against the occurrence of delta or alpha variants of SARS-CoV-2 infection: a test-negative case-control studySARS-COV-2 감염의 델타 또는 알파 변이체의 발생에 대한 자연 및 유도 면역의 보호 작용 : 테스트 음성 사례 관리 연구Research Article Published on 2022-02-082022-09-10 Journal: BMC Medicine [Category] COVID19(2023년), Fulltext, MERS, SARS, 변종, [키워드] 1:1 95% CI 95% confidence interval affected age Alpha Alpha variant association case-control study caused Complete completion database delta variant diagnose dose effort Evidence evidence of Evolution of SARS-CoV-2 exposure to Gender healthcare immunization Infection infection with SARS-CoV-2 Italian Logistic regression lombardy Lower Measures molecular molecular test new infection Occurrence performed public health reduced Region Reinfection Relative risk Result risk risk reduction SARS-CoV-2 SARS-CoV-2 variants Significant significant difference significant differences supplementary material Support supported vaccinal vaccination Vaccinations Vaccine variant variants variants of SARS-CoV-2 [DOI] 10.1186/s12916-022-02262-y PMC 바로가기 [Article Type] Research Article
Pulmonary Delivery of Aerosolized Chloroquine and Hydroxychloroquine to Treat COVID-19: In Vitro Experimentation to Human Dosing PredictionsCOVID-19를 치료하기 위해 에어로졸 화 클로로퀸 및 하이드 록시 클로로 퀴인의 폐 전달 : 인간 투약 예측에 대한 시험 관내 실험Research Article Published on 2022-02-072022-09-10 Journal: The AAPS Journal [Category] 신약개발, [키워드] Abstract acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration aerosol Aerosols bronchial epithelial cell Cell cell viability characterized Chloroquine Clinical significance Concentration concentrations coronavirus COVID-19 delivery dose Dosing drug effective Efficacy electrical resistance epithelial cells evaluated exposure to Human humans Hydroxychloroquine in vitro inhalation Inhaled Local lung lysosomal oral administration PBPK pharmacokinetic pharmacokinetics pharmacological physicochemical property predicted prediction primary human bronchial epithelial cells pulmonary respiratory respiratory tract SARS-CoV-2 severe acute respiratory syndrome Coronavirus significant changes in supplementary material target tissue thermal these compound these compounds tissue Toxicity transepithelial electrical resistance treat viability [DOI] 10.1208/s12248-021-00666-x PMC 바로가기 [Article Type] Research Article
Children and Adults With Mild COVID-19: Dynamics of the Memory T Cell Response up to 10 Months경증 COVID-19가 있는 어린이 및 성인: 최대 10개월까지 기억 T 세포 반응의 역동성Clinical Trial Published on 2022-02-072022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 임상, 치료기술, 치료법, [키워드] activated Activation acute respiratory syndrome acute respiratory syndrome coronavirus Adaptive immunity Adults Analysis Antibody Response Antigen CD4 Cell cellular children Concentration concentrations contribute controls Coronavirus-2 correlated Course COVID-19 Cytokines detectable determine develop Dynamics effective effector memory ELISPOT exposure to frequencies heat heat-inactivated IFN-γ IFN-γ ELISPOT IgG immune memory infected children infections Longitudinal assessment marker memory T memory T cell Mild mild SARS-CoV-2 infection mild symptoms Mild-to-moderate moderate moderate symptoms Month Nucleocapsid proteins overlapping PBMC PBMCs peptide peptides performed Peripheral blood peripheral blood samples recall reduced Reinfection respiratory response Result SARS-CoV-2 SARS-CoV-2 antigens SARS-COV-2 infection SARS-CoV-2-specific T cell SARS-CoV-2-specific T cells serum antibody severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 significantly Stimulation symptom onset Symptoms T cell T cell immunity T cell response T cells Th1 phenotype [DOI] 10.3389/fimmu.2022.817876 PMC 바로가기 [Article Type] Clinical Trial
Prevalences of SARS-CoV-2 RNA and anti-SARS-CoV-2 among at-risk populations in Chiang Mai and Lamphun provinces, Thailand, during November 2020–January 20212020년 11월부터 2021년 1월까지 태국 치앙마이 및 람푼 주의 위험 인구 중 SARS-CoV-2 RNA 및 항 SARS-CoV-2의 유병률Observational Study Published on 2022-02-022022-09-12 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] 95% CI Active surveillance acute respiratory syndrome acute respiratory syndrome coronavirus Analysis anti-SARS-CoV-2 antibody Asymptomatic being benefit blood sample Blood samples China conducted Confidence intervals contribute coronavirus COVID-19 cross-sectional demographic data exposure to Factor Factors help IgG IgG antibodies IgM IgM/IgG Infection Lateral flow immunoassays multivariable logistic regression Multivariable logistic regression analysis observational study outbreak participant Population positive Prevalence proportion questionnaire risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA second wave Spread susceptible swab sample swab samples symptomatic individual tested vaccination Vaccine virus was collected were used [DOI] 10.1371/journal.pone.0263127 PMC 바로가기 [Article Type] Observational Study
Risk of Severe Acute Respiratory Syndrome Coronavirus 2 Acquisition Is Associated With Individual Exposure but Not Community-Level TransmissionRandomized Controlled Trial Published on 2022-02-022022-10-04 Journal: The Journal of Infectious Diseases [Category] SARS, 임상, [키워드] 95% confidence interval acute respiratory syndrome Analysis calculated close contact Community Contact contribute coronavirus coronavirus 2 COVID-19 decrease elevated Enrollment examined exposure exposure to healthcare healthcare worker healthcare worker transmission higher risk household transmission Hydroxychloroquine incidence Increased increased risk index case individual Infection Intervention Poisson regression polymerase chain Postexposure Prophylaxis questionnaire Randomized controlled trial Relative risk respiratory Result risk risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 transmission significantly significantly increased Swab Transmission Trial [DOI] 10.1093/infdis/jiac029 PMC 바로가기 [Article Type] Randomized Controlled Trial
Modeling the factors that influence exposure to SARS-CoV-2 on a subway train carriage지하철 열차에서 SARS-CoV-2 노출에 영향을 미치는 요인 모델링Review Published on 2022-02-012022-09-11 Journal: Indoor air [Category] COVID19(2023년), SARS, 변종, [키워드] aerosol Aerosols airborne assumption can not carriage close-range Contact contact with contaminated surfaces dose droplet transmission event exposure to Factor fomite highest homogeneous individuals infection risk infectious source modeling parameter predicted Prevalence reduced reducing Result resulting SARS-CoV-2 SARS-CoV-2 modeling short duration Simulation social distancing subway subway train carriage. vaccination rates variant Ventilation virus [DOI] 10.1111/ina.12976 PMC 바로가기 [Article Type] Review
Humoral and cell-mediated response against SARS-CoV-2 variants elicited by mRNA vaccine BNT162b2 in healthcare workers: a longitudinal observational study의료 종사자에서 mRNA 백신 BNT162b2에 의해 유발된 SARS-CoV-2 변이체에 대한 체액 및 세포 매개 반응: 종단적 관찰 연구Observational Study Published on 2022-02-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration affected antibody Antibody Response BNT162b2 BNT162b2 vaccine cell-mediated response coronavirus detectable dose effective elicit elicited evaluated exposure to Frequency healthcare healthcare worker humoral Humoral response Increased Increased immunogenicity investigated less mRNA mRNA BNT162b2 vaccine mRNA vaccine Neutralizing antibodies neutralizing antibody no significant difference positive reference strain respiratory Responder responders SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants second dose second dose of vaccine sera severe acute respiratory syndrome Coronavirus Strains subject subjects subset sustained T cell T cells T-cell T-cell Response T-cell responses tested the SARS-CoV-2 the vaccine vaccination Vaccine variant variants Viral viral variant Viral variants [DOI] 10.1016/j.cmi.2021.09.016 PMC 바로가기 [Article Type] Observational Study
COVID-19 infodemic and depressive symptoms: The impact of the exposure to news about COVID-19 on the general Paraguayan populationCOVID-19 인포데믹 및 우울 증상: COVID-19에 대한 뉴스 노출이 파라과이 일반 인구에 미치는 영향Article Published on 2022-02-012022-09-11 Journal: Journal of affective disorders [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI COVID-19 COVID-19 pandemic cross-sectional cross-sectional study cut-off cut-off point Depression depressive depressive symptom Depressive symptoms develop exposure to Facebook General population Google infodemic information Instagram mental health mental health issue mental health issues mentally ill NEWS News. patients physical reported Responder responders severe symptom severe symptoms Stressor WhatsApp women [DOI] 10.1016/j.jad.2021.11.036 PMC 바로가기 [Article Type] Article
SARS-CoV-2: Can sunlight exposure reduce the risk of developing severe consequences of COVID-19?SARS-CoV-2: 햇빛 노출이 COVID-19의 심각한 결과를 초래할 위험을 줄일 수 있습니까?Article Published on 2022-02-012022-09-11 Journal: Computational biology and chemistry [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] addition Can CCR2 consequence COVID-19 disease severity DPP9 explain exposure to Exposure to sunlight Genetic changes host gene expression HSPA1L IFNAR2 modulate OAS1 Radiation reduce risk SARS-CoV-2 suggested Sunlight TYK2 UVB radiation. Viral load virus [DOI] 10.1016/j.compbiolchem.2021.107602 PMC 바로가기 [Article Type] Article
Surveillance of Rodent Pests for SARS-CoV-2 and Other Coronaviruses, Hong KongSARS-CoV-2 및 기타 코로나바이러스에 대한 설치류 해충 감시, 홍콩Research Letter Published on 2022-02-012022-09-10 Journal: Emerging Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 can not China conducted coronavirus coronavirus disease COVID-19 detect exposure to Hong Kong Other Pest Potential respiratory respiratory infections rodent rodents SARS-CoV-2 SARS-CoV-2 RNA seropositive Serosurveillance severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Surveillance urban public health virus viruses zoonoses [DOI] 10.3201/eid2802.211586 PMC 바로가기 [Article Type] Research Letter