Integro-differential approach for modeling the COVID-19 dynamics – Impact of confinement measures in ItalyCOVID-19 역학 모델링을 위한 적분-차동 접근법 - 이탈리아의 격리 조치의 영향Article Published on 2021-12-012022-09-11 Journal: Computers in biology and medicine [Category] SARS, 변종, 치료기술, [키워드] adoption approach available data coefficient complicate condition conditions consequence Contagion Containment measure containment measures country COVID-19 COVID-19 epidemic COVID-19 pandemic criteria deaths detectable disorganized doctrine driven by Effectiveness English Epidemic Evolution failure Government health system health systems highlighting Impact incisive indication Infection involved Italian region Italian regions Italy lack limit management mathematical Mathematical modelling measure parameter parameters predict Propagation reactivity regions reliability robust SARS-CoV-2 security Spread stability Transmissibility Vaccinations Variability variant virus variants zone [DOI] 10.1016/j.compbiomed.2021.105013 PMC 바로가기 [Article Type] Article
Toxic Metabolic Encephalopathy in Hospitalized Patients with COVID-19Observational Study Published on 2021-12-012022-10-05 Journal: Neurocritical care [Category] SARS, 임상, [키워드] 95% CI 95% confidence interval acute respiratory syndrome adjusted hazard ratio Admission age Altered mental status assessment Brain Care conducted confounders confounding factors Confusion coronavirus coronavirus disease COVID-19 Cox proportional hazard delirium Dementia diagnose diagnosed died discharged home disease eight Encephalopathy etiologies etiology failure Health highest hospital Hospital admission Hospitalized hospitalized patient Hypoxemia identify In-hospital death in-hospital mortality include increased risk intensive care Intubated intubation less Mental status metabolic mortality rate multicenter multifactorial Multiple multivariable neurological New York City Observational cohort study occurred Older outcome Patient patients patients with COVID-19 Prevalence psychiatric history remained reported retrospective risk SARS-CoV-2 SARS-COV-2 infection Sedation Seizures Sepsis Sex stratified toxic uremia were excluded with COVID-19 [DOI] 10.1007/s12028-021-01220-5 PMC 바로가기 [Article Type] Observational Study
Effect of High-Titer Convalescent Plasma on Progression to Severe Respiratory Failure or Death in Hospitalized Patients With COVID-19 Pneumonia A Randomized Clinical TrialCOVID-19 폐렴을 가진 입원 환자에서 중증 호흡 부전 또는 사망으로의 진행에 대한 하이 튜터 회복기 혈장의 효과 무작위 임상 시험Randomized Controlled Trial Published on 2021-11-292022-08-13 Journal: JAMA Network Open [Category] MERS, SARS, 임상, [키워드] 1:1 95% CI Adverse adverse events age clinical clinical end point clinical trial Composite control group convalescent plasma convalescent plasma group COVID-19 COVID-19 pneumonia CP and ST CP group CP plus ST CP plus standard therapy death defined did not reduce Effect Efficacy eligible enrolled Enrollment evaluate event experimental group failure finding fraction Glucocorticoids heparin high-titer anti–SARS-CoV-2 CP high-titer CP hospitalized patient hospitalized patients Importance infused intravenous IQR Italy Low–molecular weight heparin maximum measure mechanical ventilation Microneutralization test moderate to severe moderate to severe COVID-19 pneumonia modified intention-to-treat not significantly different objective occurred Odds ratio Open-label oxygen partial pressure participant Patient patients patients with COVID-19 patients with moderate plasma Pneumonia Point primary end point Primary outcome progression randomization randomized clinical trial randomized patient receive recommendations Registration Relevance Remdesivir respiratory Respiratory failure Result setting Severe COVID-19 pneumonia severe respiratory failure ST alone standard care Standard therapy the median treat treated Trial Volume volume of infused CP with COVID-19 worsening worsening respiratory failure [DOI] 10.1001/jamanetworkopen.2021.36246 PMC 바로가기 [Article Type] Randomized Controlled Trial
The Impact of COVID-19 Pandemic on Management and Outcome in Patients with Heart FailureArticle Published on 2021-11-272022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] absence addressed affected age cardiovascular Care Clinical management Cohort Comorbidities competing COVID-19 COVID-19 pandemic death deaths decrease diabete Diagnosis died disease Effect evaluated failure functional Health Health Service heart heart failure Hospitalization hospitalizations Impact infected with COVID-19 initial lockdowns Male sex management medical service morbidity and mortality Mortality mortality rate Non-COVID-19 obesity outcome overall mortality pandemic Patient reduced renal dysfunction replaced respiratory infection SARS-CoV-2 significantly social distancing study period survival rate were infected with COVID-19 [DOI] 10.3390/jcm10235577 PMC 바로가기 [Article Type] Article
Heart Failure Probability and Early Outcomes of Critically Ill Patients With COVID-19: A Prospective, Multicenter StudyCardiovascular Medicine Published on 2021-11-262022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] 95% CI age albumin all-cause mortality analyzed applied assist bootstrap C-index cardiac function clinical suspicion coronavirus disease COVID-19 Critically ill patient enrolled failure Follow-up heart heart failure highlighting Ill IMPROVE In-hospital death laboratory-confirmed lymphocyte Mortality mortality rate multicenter multicenter study multivariate logistic regression nomogram NT-proBNP operator outcome Patient patients died predict Predictive predominant Primary outcome Probability Prognosis Prospective Prospective Study risk factor risk stratification screened significantly higher the patient total bilirubin unlikely with COVID-19 zone [DOI] 10.3389/fcvm.2021.738814 PMC 바로가기 [Article Type] Cardiovascular Medicine
Use and misuse of biomarkers and the role of D-dimer and C-reactive protein in the management of COVID-19: A post-hoc analysis of a prospective cohort study바이오 마커의 사용 및 오용 및 COVID-19의 관리에서 D- 차이 및 C- 반응성 단백질의 역할 : 전향 적 코호트 연구의 사후 분석Original Article Published on 2021-11-242022-08-31 Journal: Clinics [Category] MERS, SARS, 바이오마커, [키워드] acute respiratory syndrome adjusted Admission age Analysis assessment association associations Biomarker Biomarkers C-reactive protein C-reactive protein (CRP Cohort studies Comorbidities Complication coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CRP CRP level CRP levels D-dimer D-dimer level death demonstrated electronic patient record Electronic patient records elevated evaluate failure FEU fibrinogen Health Care Costs high mortality hospital hospital cost Hospital mortality hospitalized patient hospitalized patients incidence indication Infection Inflammatory Inpatient Inpatients Laboratory lead logistic regression model management Mortality number of comorbidities Occurrence Odds ratio patient records post-hoc analysis predicted Prognosis prospective cohort study respiratory sequential organ failure assessment score severe acute respiratory syndrome Coronavirus Sex statistically significant systemic inflammatory thrombotic Trigger Venous Thromboembolism VTE were used with COVID-19 [DOI] 10.6061/clinics/2021/e3547 PMC 바로가기 [Article Type] Original Article
Comparison of mortality risk evaluation tools efficacy in critically ill COVID-19 patientsResearch Article Published on 2021-11-222022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] 4C mortality score 95% CI Accuracy Admission age Analysis APACHE II assessment AUC value average calculated can be used chronic Combination COVID-19 COVID-19 pandemic COVID-19 patient Critically ill demonstrated determine Efficacy failure Final hospital ICU ICU Patients increase in independent intensive care male Mortality mortality risk Non-survivors Patient Physiology predict Predictive predictor regression analysis Result Retrospective study risk score Risk scores score SOFA survivor treated was performed [DOI] 10.1186/s12879-021-06866-2 PMC 바로가기 [Article Type] Research Article
Clinical characteristics and outcomes of COVID-19 patients admitted to the intensive care unit during the first year of the pandemic in Brazil: a single center retrospective cohort studyOriginal Article Published on 2021-11-192022-10-31 Journal: Einstein [Category] COVID-19, SARS, [키워드] age assessment Betacoronavírus Betacoronavirus Brazil Characteristics Charlson Comorbidity Index clinical Clinical characteristics cohort study Comorbidity conducted Coronavírus coronavirus Coronavirus infections COVID-19 COVID-19 patient critical care outcomes died discharged exhibited extracorporeal membrane oxygenation failure hospital hospital discharge Hospital stay identify in-hospital mortality Infecções por coronavírus intensive care intensive care units interquartile range mechanical ventilation morbidity and mortality Mortalidade Mortality nasal non-survivor Non-survivors Noninvasive ventilation Older organ support outcome outcomes Oxigenação por membrana extracorpórea pacientes com COVID-19 pandemic Patient patients with COVID-19 Physiology predictor prolonged intensive care renal renal replacement therapy resource Respiração artificial Respiration, artificial Resultados de cuidados críticos retrospective cohort study SARS-CoV-2 score severe COVID-19 single center single-center study period Support survivor Survivors Unidades de terapia intensiva Ventilação não invasiva with COVID-19 [DOI] 10.31744/einstein_journal/2021AO6739 PMC 바로가기 [Article Type] Original Article
Kinetics of antibody response in critically ill patients with Middle East respiratory syndrome and association with mortality and viral clearanceArticle Published on 2021-11-192022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, [키워드] 95% CI Admission admitted to ICU antibody Antibody Response Antigen assessment association blood sample clearance coated with collected Corticosteroids Critically ill Critically ill patient Diseases ELISA enzyme-linked immunosorbent failure faster ICU IgG antibody immunology Immunotherapy implication invasive ventilation Kinetics lower mortality median MERS MERS patient MERS-CoV MERS-CoV RNA MERS-CoV S1 Middle East Mortality onset of symptom optical Pathogenesis Patient renal replacement therapy rRT-PCR significantly increased Signs and symptoms SOFA study cohort syndrome vasopressors viral clearance [DOI] 10.1038/s41598-021-01083-y PMC 바로가기 [Article Type] Article
An Investigation of the Initial Recovery Time of Chinese Enterprises Affected by COVID-19 Using an Accelerated Failure Time ModelArticle Published on 2021-11-172022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, [키워드] accelerated accelerated failure time model acceleration adopted affecting affecting factors Analysis China Chinese covariate COVID-19 distribution Effect Factor Factors failure Government initial initial recovery investigation less Model pandemic Panic Perspective Probability provide questionnaire Specific Support survival survival analysis time [DOI] 10.3390/ijerph182212079 PMC 바로가기 [Article Type] Article