ABO Blood Types and COVID-19: Spurious, Anecdotal, or Truly Important Relationships? A Reasoned Review of Available DataABO 혈액형과 COVID-19: 가짜, 일화 또는 진정으로 중요한 관계? 사용 가능한 데이터에 대한 합리적인 검토Review Published on 2021-01-222022-09-01 Journal: Viruses [Category] 진단, [키워드] ABO ABO blood groups Anecdotal antibody Antigen appear association attack rate Blood Blood Group blood group system Blood types Coefficient of variation Consensus COVID-19 COVID-19 pandemic determine detrimental discrepancies expected explain explained frequencies Frequency geographical areas hypothese hypotheses individual individuals less lower risk lung dysfunction mechanism natural antibodies phenotype Population population level Prevalence Protective reported review risk risk differences SARS-CoV-2 virion SARS-CoV-2 virions second Spurious Subtypes susceptibility thrombosis Topic Type Variation vascular dysfunction virus transmission with COVID-19 [DOI] 10.3390/v13020160 PMC 바로가기 [Article Type] Review
Knowledge About COVID-19 in Brazil: Cross-Sectional Web-Based StudyOriginal Paper Published on 2021-01-212022-10-04 Journal: JMIR Public Health and Surveillance [Category] MERS, 신약개발, [키워드] Administered affected age analyzed association average Brazil Brazilian Care caused coronavirus country COVID-19 cross-sectional death disease dissimilarity distributions evaluate evaluated Facebook FIVE frequencies groups had more health information identify Infection information Intervention knowledge less measure media medication medications Ministry of Health MOST North objective online survey participant Perception platform Population question questionnaire recorded recruited Region response Result risk SARS-CoV-2 Sex significance level similarity social distancing South South America Spread statistical test Study design Symptoms the disease total score Transmission Vaccine variable virus was used website were recorded WhatsApp women [DOI] 10.2196/24756 PMC 바로가기 [Article Type] Original Paper
Evidence for Strong Mutation Bias toward, and Selection against, U Content in SARS-CoV-2: Implications for Vaccine DesignSARS-CoV-2의 U 콘텐츠에 대한 강한 돌연변이 편향 및 선택에 대한 증거: 백신 설계에 대한 의미Discoveries Published on 2021-01-202022-09-10 Journal: Molecular Biology and Evolution [Category] 변종, 유전자 메커니즘, [키워드] accounting Analysis approach attenuation Bia Codons content CpG dinucleotide dinucleotides direction DNA vaccines Ebola Effect Engineering expected expression frequencies generalization generate H1N1 include indicate mechanism mRNA stability Mutation mutation equilibrium Neutral neutrality nucleotide observé profile quarter SARS-CoV-2 SARS-CoV-2 genes Selection Strong synonymous synonymous mutations synthesis turn Usage Vaccine Vaccine design Viral viral attenuation viral genes virus viruses Whole-genome sequence whole-genome sequences [DOI] 10.1093/molbev/msaa188 PMC 바로가기 [Article Type] Discoveries
Routine saliva testing for the identification of silent coronavirus disease 2019 (COVID-19) in healthcare workers의료 종사자의 침묵 코로나바이러스 질병 2019(COVID-19) 식별을 위한 일상적인 타액 검사Original Article Published on 2021-01-112022-09-10 Journal: Infection Control and Hospital Epidemiology [Category] MERS, SARS, 치료기술, [키워드] average case detection coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 guideline COVID-19 patient current determine frequencies Frequency frontline healthcare worker frontline healthcare workers healthcare healthcare personnel healthcare worker help highlight identify nasopharyngeal noninvasive nursing homes outbreak Patient percentage populations presymptomatic Prevent Probability PROTECT reported routine Saliva sensitivity silent silent infection silent infections Simulation symptomatic Testing utility [DOI] 10.1017/ice.2020.1413 PMC 바로가기 [Article Type] Original Article
No credible evidence for links between 2D:4D and COVID-19 outcomes: A probabilistic perspective on digit ratio, ACE variants, and national case fatalities2D:4D와 COVID-19 결과 사이의 연관성에 대한 신뢰할 수 있는 증거 없음: 숫자 비율, ACE 변종 및 전국 사례 사망률에 대한 확률론적 관점Article Published on 2021-01-012022-09-11 Journal: Early human development [Category] 변종, [키워드] 2D:4D absence ACE ACE1 ACE2 allele androgen angiotensin Angiotensin-converting enzyme article articles association Bayesian Bayesian analysis Bayesian inference COVID-19 COVID-19 mortality COVID-19 susceptibility Critical described digit ratio Digit ratio. evaluated Evidence evidence of fatality female frequencies Frequency Genotype Grounding Hypothesis male National offer outcome outcomes Perspective prenatal Prevalence prognostic robust second wave statistical statistical inference suggested utility variant variants [DOI] 10.1016/j.earlhumdev.2020.105272 PMC 바로가기 [Article Type] Article
Characteristics and clinical outcomes of COVID-19 patients in an underserved-inner city population: A single tertiary center cohort서비스가 부족한 도심 인구에서 COVID-19 환자의 특성 및 임상 결과: 단일 3차 센터 코호트Article Published on 2021-01-012022-09-11 Journal: Journal of medical virology [Category] SARS, 바이오마커, 진단, 치료제, [키워드] 95% CI 95% confidence interval African American age association Asthma baseline Biomarker Biomarkers Characteristics Clinical outcome clinical outcomes Cohort Comorbidities Continuous renal replacement therapy COPD coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 patient CRP CRP level CRP levels CRRT Data collection death demographic Descriptive statistics determine deviation diabetes Diabetes Mellitus disease severity female frequencies Hemodialysis higher risk hospitalized patient hospitalized patients hypertension independent risk factor Infection information inner city hospital Inpatient Laboratory mechanical ventilation Mortality multivariate logistic regression occurred Odds ratio Older age outcomes Patient renal required Requirement retrospective risk factor Risk factors significantly single-center study The United States Treatment United States urban area Vasopressor vasopressors were used with COVID-19 [DOI] 10.1002/jmv.26252 PMC 바로가기 [Article Type] Article
Structural Variability, Expression Profile, and Pharmacogenetic Properties of TMPRSS2 Gene as a Potential Target for COVID-19 TherapyCOVID-19 치료의 잠재적 표적인 TMPRSS2 유전자의 구조적 다양성, 발현 프로필 및 약리학적 특성Article Published on 2020-12-252022-09-10 Journal: Genes [Category] MERS, SARS, 변종, 치료기술, 치료제, [키워드] ACE2 acetaminophen acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition alveolar cell alveolar cells Analysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Asian Basigin BSG co-expressed copy number copy number variant coronavirus COVID-19 COVID-19 therapy Curcumin distribution downregulate drug enzyme European populations ExoN expression expression levels frequencies Frequency genome-wide data human cells human population human populations Interaction interactions involved lung microRNA MicroRNAs Missense mutation Paracetamol pharmacotranscriptomics Polymorphisms Population Potential predicted priming profile profiles property Prostate cancer Protein ranged receptor regulate Regulation respiratory respiratory tract cells SARS-CoV-2 SARS-CoV-2 cell Serine serine 2 serine protease severe acute respiratory syndrome Coronavirus significantly higher Single-cell RNA sequencing single-nucleotide Single-nucleotide polymorphisms SNV target therapy tissue-specific expression TMPRSS2 Variability [DOI] 10.3390/genes12010019 PMC 바로가기 [Article Type] Article
Class I HLA Allele Predicted Restricted Antigenic Coverages for Spike and Nucleocapsid Proteins Are Associated With Deaths Related to COVID-19클래스 I HLA 대립유전자 예측 스파이크 및 뉴클레오캡시드 단백질에 대한 제한된 항원 범위는 COVID-19와 관련된 사망과 관련되어 있습니다Immunology Published on 2020-12-162022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 치료법, [키워드] addition allele frequency Amino acid analyzed Antigen antigens approach association best Betacoronavirus class Clustering contribute coronavirus coronavirus strains correlated country Coverage COVID-19 death distribution elevated epidemiological data etiological agent frequencies herd immunity HLA HLA allele HLA alleles HLA-A HLA-B Immunity in silico insertion knowledge landscape ligandome lowest mortality rate mortality rates not affect number of deaths outcome Pandemics peptide peptides population coverage analysis potential risk predicted respond Restricted SARS-CoV-2 severity spike Spread spread to the disease These data Vaccine with COVID-19 [DOI] 10.3389/fimmu.2020.565730 PMC 바로가기 [Article Type] Immunology
Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysisArticle Published on 2020-12-092022-10-04 Journal: Nature Communications [Category] MERS, SARS, 변종, 유전자 메커니즘, [키워드] Accuracy Analysis controls coronavirus 2 Coverage COVID-19 Critical detect elevated error rate Evidence Evolution facilitate frequencies Illumina improvement INDEL International Local Nanopore nanopore sequencing National Next-generation sequencing ONT Oxford Nanopore Technology Patient platform Precision provide public health respiratory RNA SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 surveillance sensitivity sequence Sequencing sequencing reads short-read sequencing Single nucleotide variant SNVs specimen Structural variation supported Transmission Validity variant Viral genetics WGS whole-genome sequencing widespread [DOI] 10.1038/s41467-020-20075-6 PMC 바로가기 [Article Type] Article
Trends of interventional radiology procedures during the COVID-19 pandemic: the first 27 weeks in the eye of the stormOriginal Article Published on 2020-12-092022-10-29 Journal: Insights into Imaging [Category] COVID-19, [키워드] Acuity approved Chi-square COVID-19 COVID-19 pandemic COVID-19 patients Demand fraction frequencies Intervention interventional IRB Mann–Whitney U test Musculoskeletal novel objective oncology outbreak pandemic Patient performed Population promote proportion radiology remained respiratory Result retrospective SARS-CoV scale Singapore statistically significant difference trend understanding while [DOI] 10.1186/s13244-020-00938-8 PMC 바로가기 [Article Type] Original Article