infiltration – Page 10 – Communicable Diseases Research

Patient with H syndrome, cardiogenic shock, multiorgan infiltration, and digital ischemia

Case Report

Published on 2021-06-302022-10-29
Journal: Pediatric Rheumatology Online Journal [Category] COVID-19, MERS, SARS,

Correlation of SARS-CoV-2 RNA in wastewater with COVID-19 disease burden in sewersheds

폐수에서 SARS-CoV-2 RNA와 하수구의 COVID-19 질병 부담의 상관관계

Article

Published on 2021-06-252022-09-11
Journal: The Science of the total environment [Category] SARS, 치료기술,

[키워드] 1.26 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 assist cause Characteristics Community conducted coronavirus coronavirus disease Correlation analysis COVID-19 COVID-19 case COVID-19 cases detectable disease Disease burden Epidemiology Evidence evidence of feces frequencies increase in individual infiltration inflow Interceptor outbreak positively correlated Public health response Public health responses Ribonucleic acid RNA SAR-CoV-2 SARS-CoV-2 SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus sewershed urban Utah utility viral ribonucleic acid virus wastewater wastewater epidemiology with COVID-19
[DOI] 10.1016/j.scitotenv.2021.145790 PMC 바로가기 [Article Type] Article

Myricetin Inhibits SARS-CoV-2 Viral Replication by Targeting M pro and Ameliorates Pulmonary Inflammation

Pharmacology

Published on 2021-06-172022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

H1N1 exposure during the convalescent stage of SARS-CoV-2 infection results in enhanced lung pathologic damage in hACE2 transgenic mice

Research Article

Published on 2021-06-132022-10-31
Journal: Emerging Microbes & Infections [Category] COVID-19, SARS, 신종인플루엔자,

Viral infiltration of pancreatic islets in patients with COVID-19

COVID-19 환자에서 췌도의 바이러스 침투

Article

Published on 2021-06-102022-09-10
Journal: Nature Communications [Category] MERS, SARS, 바이오마커, 진단, 치료기술, 치료법,

[키워드] absence ACE2 Autopsy Cell Complication comprehensive analysis contribute COVID-19 patient COVID-19 patients detectable diabete diabetes disease DPP4 dysregulation electron microscopy Endocrine examined expressed expression facilitate Factors hyperglycemia Immune cell infiltration immunofluorescence immunohistochemistry increased risk Infection infiltration islet cell islet cells mechanism metabolic Metabolic diseases Microscopy necroptotic cell death NRP1 pancreatic pancreatic beta-cell pancreatic beta-cells pancreatic islet patients patients with COVID-19 performed pseudoviruses receptor RNA SARS-CoV-2 SARS-CoV-2 pseudoviruses SARS-CoV-2 viral SARS-CoV-2 viral infection severe COVID-19 tissue TMPRSS vasculature Viral viral infection virus entry
[DOI] 10.1038/s41467-021-23886-3 PMC 바로가기 [Article Type] Article

The Current Status and Challenges in the Development of Vaccines and Drugs against Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2)

Review

Published on 2021-06-012022-10-27
Journal: BioMed Research International [Category] Coronavirus, COVID-19, MERS, SARS,

[키워드] acute respiratory distress addition addressed Angiotensin-converting enzyme Antibody-dependent enhancement bind cause challenge change characterized Clinical management clinical manifestation clinically Complete complications of COVID-19 Coronavirus disease-19 COVID-19 COVID-19 patient COVID-19 patients current Cytokine storm described develop development drug effective eosinophil greater Hypothesis Immunity immunopathological include individual Infection infiltration lack lung lymphopenia management mechanism mechanisms membrane molecular mononuclear cell mutant pathogenesis of SARS-CoV-2 pathophysiology patients Pneumonia Prevent protease PROTECT provide reduce Replication Research respiratory S glycoprotein SARS-CoV-2 serological test Spread status T cell tested the antibody response therapeutic therapeutic intervention Treatment understanding Vaccine variant variants of SARS-CoV-2 variations Viral load virulence virus virus transmission
[DOI] 10.1155/2021/8160860 PMC 바로가기 [Article Type] Review

The Current Status and Challenges in the Development of Vaccines and Drugs against Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2)

중증 급성 호흡기 증후군-코로나 바이러스 -2 (SARS-COV-2)에 대한 백신 및 약물의 발달의 현재 상태와 도전.

Review

Published on 2021-06-012022-09-10
Journal: BioMed Research International [Category] 변종, 신약개발, 진단, 치료기술,

[키워드] acute respiratory distress addition addressed angiotensin Angiotensin-converting enzyme Antibody Response Antibody-dependent enhancement bind cause challenge change characterized Clinical management clinical manifestation clinical manifestations clinically Complete complications of COVID-19 coronavirus coronavirus disease Coronavirus disease-19 COVID-19 COVID-19 patient COVID-19 patients current Cytokine storm described develop development drug effective eosinophil greater Hypothesis Immunity immunopathological include individual Infection infiltration lack lung Lungs lymphopenia management mechanism mechanisms membrane molecular molecular and serological tests mononuclear cell mutant pathogenesis of SARS-CoV-2 pathophysiology patients Pneumonia Prevent protease PROTECT provide reduce Replication Research respiratory respiratory distress S glycoprotein SARS-CoV-2 serological test Serological tests Severe acute respiratory syndrome severe acute respiratory syndrome-coronavirus-2 Spread status T cell tested the antibody response therapeutic therapeutic intervention Treatment treatment of COVID-19 patients understanding Vaccine variant variants of SARS-CoV-2 variations Viral Viral load virulence virus virus transmission
[DOI] 10.1155/2021/8160860 PMC 바로가기 [Article Type] Review

The Current Status and Challenges in the Development of Vaccines and Drugs against Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2)

Review

Published on 2021-06-012022-10-27
Journal: BioMed Research International [Category] COVID-19,

[키워드] acute respiratory distress addition addressed Angiotensin-converting enzyme Antibody-dependent enhancement bind cause challenge change characterized Clinical management clinical manifestation clinically Complete complications of COVID-19 Coronavirus disease-19 COVID-19 COVID-19 patient COVID-19 patients current Cytokine storm described develop development drug effective eosinophil greater Hypothesis Immunity immunopathological include individual Infection infiltration lack lung lymphopenia management mechanism mechanisms membrane molecular mononuclear cell mutant pathogenesis of SARS-CoV-2 pathophysiology patients Pneumonia Prevent protease PROTECT provide reduce Replication Research respiratory S glycoprotein SARS-CoV-2 serological test Spread status T cell tested the antibody response therapeutic therapeutic intervention Treatment understanding Vaccine variant variants of SARS-CoV-2 variations Viral load virulence virus virus transmission
[DOI] 10.1155/2021/8160860 PMC 바로가기 [Article Type] Review

Transcriptional Changes in CD16+ Monocytes May Contribute to the Pathogenesis of COVID-19

CD16+ 단핵구의 전사 변화가 COVID-19의 발병에 기여할 수 있음

Immunology

Published on 2021-05-242022-09-11
Journal: Frontiers in Immunology [Category] SARS, 유전자 메커니즘,

[키워드] analyzed Antigen presentation apoptotic caused CD16 CD16+ CD16+ monocyte CD16+ monocytes Cell cell activation cell movement change changes in characterized contribute contributing to COVID-19 COVID-19 case COVID-19 cases COVID-19 pandemic death dysregulated dysregulated immune response elevated expressed expression function functions gene signatures Genes healthy individual healthy individuals host response immune cells infiltration Inflammation Inflammatory Inflammatory response Inflammatory responses innate immune cell Innate immune cells interferon interferon response involved MHC class mild case mild cases mitochondrial Monocytes Non-classical monocytes Pathogenesis PBMC people with COVID-19 phenotype RNA sequencing data SARS-CoV-2 Severe case severe cases severity severity of COVID-19 Single Cell Single-cell transcriptomics the disease These cells tissue repair tissues transcriptional change Transcriptional changes transcriptomic upregulated upregulation Viral viral infections
[DOI] 10.3389/fimmu.2021.665773 PMC 바로가기 [Article Type] Immunology

Type I and III IFNs produced by the nasal epithelia and dimmed inflammation are features of alpacas resolving MERS-CoV infection

Research Article

Published on 2021-05-242022-10-29
Journal: PLoS Pathogens [Category] COVID-19,

[키워드] Adaptive immune response anti-inflammatory cytokine anti-inflammatory effect antiviral drug Asymptomatic Asymptomatic carriers CCL2 CCL3 chemokine clearance clinical manifestation Concomitant contribute correlated Cytokine storm disease driving effective elicited epithelia etiological agent expression feature high mortality Host humans IFN IL10 immune response gene immunological pathway Infection Infectious virus infiltration Inflammation Inflammatory responses innate immune response interferon interferon response interferons (IFNs ISG ISGs lethal disease leukocyte leukocytes lung MERS-CoV MERS-CoV infection Middle East Mild mucosa nasal nasal mucosa NF-κB post inoculation pro-inflammatory cytokine pro-inflammatory gene produced provoke Regulation reservoir Respiratory disease respiratory syndrome coronavirus respiratory tract Simultaneous stimulated syndrome tissue damage tissues transcribed Transcription transcriptional regulation triggering Type type I Type III IFN understanding upregulation Vaccines viral infection virus virus clearance while
[DOI] 10.1371/journal.ppat.1009229 PMC 바로가기 [Article Type] Research Article