Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: A cohort study using linked primary care, secondary care, and death registration data in the OpenSAFELY platform영국에서 COVID-19 입원 후 전반적이고 원인 별 입원 및 사망 : Obensafely 플랫폼에서 연결된 1 차 진료, 2 차 치료 및 사망 등록 데이터를 사용한 코호트 연구Research Article Published on 2022-01-252022-09-10 Journal: PLoS Medicine [Category] 변종, [키워드] adjusted adjusted hazard ratio Admission adverse outcome age all-cause mortality approval causes clinician cohort study Comorbidities Comorbidity conducted Control controls Coronavirus disease 2019 COVID-19 COVID-19 group COVID-19 hospitalisation COVID-19 patient COVID-19 patients Cox regression death Dementia demographic characteristics Deprivation discharge discharged Ethnicity events Evidence Factor General population greater Health health problems healthcare higher risk highest highlighting hospital Hospital admission hospital discharge hospitalisation hospitalisations hospitalised illnesses in some individual infected with SARS-CoV-2 Infection Influenza initial limitation Lower respiratory tract lower respiratory tract infection lower risk male matched controls median age medium mental health Mortality MOST obesity OpenSAFELY outcome outcomes pandemic Patient patients platform Policy potential risk primary care problem problems public health raised rates of infection readmission researcher resources respiratory risk risk of death secondary care severe COVID-19 Sex significantly smoking status subsequent suggested survivor variants with COVID-19 [DOI] 10.1371/journal.pmed.1003871 PMC 바로가기 [Article Type] Research Article
Association of a Third Dose of BNT162b2 Vaccine With Incidence of SARS-CoV-2 Infection Among Health Care Workers in Israel이스라엘의 의료 종사자 중 SARS-CoV-2 감염 발생률이 있는 BNT162b2 백신 3차 접종의 연관성Article Published on 2022-01-252022-09-12 Journal: JAMA [Category] 진단, [키워드] 95% CI adjusted hazard ratio administration age Analysis association Aviv baseline BNT162b2 booster dose conducted Cox regression Cox regression analysis Effectiveness enrolled Enrollment Final Follow-up hazard ratio Health care worker health care workers IgG titer incidence rate individual IQR lower risk median occurred of BNT162b2 Older outcome participant Participants Pfizer-BioNTech Primary outcome prospective cohort study Protein receiving Receptor binding domain reported required SARS-CoV-2 SARS-COV-2 infection Screening significantly significantly lower single center study cohort study enrollment Surveillance symptomatic the median vaccinated individual vaccination Vaccine was performed was used women worker [DOI] 10.1001/jama.2021.23641 PMC 바로가기 [Article Type] Article
Pro108Ser mutation of SARS-CoV-2 3CL pro reduces the enzyme activity and ameliorates the clinical severity of COVID-19SARS-COV-2 3CL PRO의 PRO108SER 돌연변이는 효소 활성을 감소시키고 COVID-19의 임상 적 심각성을 개선시킨다.Article Published on 2022-01-252022-09-10 Journal: Scientific Reports [Category] 변종, 유전자 메커니즘, 임상, 진단, 치료기술, 치료법, 치료제, [키워드] 3CL pro Amino acid amino acid residue characterization chymotrypsin Clinical course Clinical severity clinical trial Controlled clinical trial COVID-19 COVID-19 in patient death demonstrated deuterium enzymatic activity enzyme enzyme activity Enzyme mechanisms hospital hydrogen infected with SARS-CoV-2 Infection inhibitor International Lineage lower risk mass spectrometry mutant Mutation oxygen oxygen supplementation Patient patients with SARS-CoV-2 PF-07321332 Placebo positioned proportion protease Randomized reduce reduced required SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strains strain Support symptom onset the patient treated Trial viral infection virus [DOI] 10.1038/s41598-022-05424-3 PMC 바로가기 [Article Type] Article
The occurrence and risk factors associated with post‐traumatic stress disorder among discharged COVID‐19 patients in Tianjin, ChinaOriginal Article Published on 2022-01-222022-10-28 Journal: Brain and Behavior [Category] COVID-19, COVID19(2023년), Fulltext, MERS, SARS, [키워드] 95% CI adjusted age applied Bacterial Binary logistic regression China clinical parameter COVID‐19 COVID‐19 infection COVID‐19 patient COVID‐19 patients COVID‐19 discharged disorder Factor female Gender hemoglobin higher risk hospital hypertension identify involved lower risk mental health multivariable analyses Occurrence old age participant Patient Pneumonia post‐traumatic stress disorder PTSD pulmonary lobe questionnaire Result risk factor serum Sex significantly smoker smoking Stress Tianjin triggered [DOI] 10.1002/brb3.2492 PMC 바로가기 [Article Type] Original Article
Evaluating the Evidence in Clinical Studies of Vitamin D in COVID-19Review Published on 2022-01-212022-10-31 Journal: Nutrients [Category] COVID-19, SARS, [키워드] 25-hydroxyvitamin D administration Asymptomatic COVID-19 benefit cholecalciferol clinical clinical study clinical trials condition Controlled trial COVID-19 COVID-19 pandemic deficiency dose Epidemiology Evaluating Evidence General population greater group hospitalized patients Infection infection rates Interaction lower risk Mild Mortality MOST nutrition observational studies observational study other treatments outcome outcomes overcome Placebo provide RCT RCTs receiving reduced reduced risk respiratory infections risk risk of COVID-19 serum severity of COVID-19 shown Study design Vitamin D Vitamin D status Vitamin D supplementation with COVID-19 [DOI] 10.3390/nu14030464 PMC 바로가기 [Article Type] Review
Oral Chinese Herbal Medicine on Immune Responses During Coronavirus Disease 2019: A Systematic Review and Meta-AnalysisMedicine Published on 2022-01-212022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] “medicine all-cause mortality analyzed approach CD3 CD4 CD4—CD8 ratio certainty of evidence Chest Chinese Chinese traditional” CHM clinical parameter Clinical practice clinical symptom Confidence intervals coronavirus disease Coronavirus disease 2019 Coronavirus infection cough COVID-19 Critical database disease Efficacy eligible evaluated fatigue Fever function Herbal heterogeneity immune effector cell immune response Immunity Immunotherapy IMPROVE Jadad scale lower risk lymphocyte lymphocyte counts Lymphocytes mean difference Medicine Meta-analysis moderate Modification Mortality Newcastle-Ottawa Scale observational studies oral outcome Patient performed profiles random effect Randomized controlled trial RCT RCTs reduced response Result review risk of bia SARS-CoV-2 searched secondary standardized mean difference Symptom systematic review therapeutic effect TNF-α Treatment was used were measured were used [DOI] 10.3389/fmed.2021.685734 PMC 바로가기 [Article Type] Medicine
Multimorbidity and adverse events of special interest associated with Covid-19 vaccines in Hong KongArticle Published on 2022-01-202022-10-04 Journal: Nature Communications [Category] 치료법, [키워드] Adverse adverse event adverse events association chronic conditions condition CoronaVac COVID-19 vaccination database defined develop Electronic health record Epidemiology event Evidence examined first dose group groups healthcare Hong Kong increased risk individual individuals lower risk Modification Multimorbidity Outcomes research Patient public health Research Result resulting retrospective cohort risk SARS-CoV-2 specific disease vaccination Vaccine Vaccines World Health Organization [DOI] 10.1038/s41467-022-28068-3 PMC 바로가기 [Article Type] Article
The impact of Movement Control Order during the COVID-19 pandemic on lifestyle behaviours and body weight changes: Findings from the MyNutriLifeCOVID-19 online surveyClinical Trial Published on 2022-01-182022-10-04 Journal: PLoS ONE [Category] 임상, [키워드] activities affected age Anthropometric data association change Community Control COVID-19 pandemic cross-sectional determine fat finding Health healthy latency less linear mixed model lockdown lower risk movement multivariable participated physical physical activity Prevent proportion reduced reported Result Sex significantly sleep quality Spread the disease was used weight loss while [DOI] 10.1371/journal.pone.0262332 PMC 바로가기 [Article Type] Clinical Trial
Comparative risk of incidence and clinical outcomes of COVID-19 among proton pump inhibitor and histamine-2 receptor antagonist short-term users: a nationwide retrospective cohort studyResearch Published on 2022-01-172022-10-28 Journal: BMC Pharmacology & Toxicology [Category] COVID-19, [키워드] Acid suppressants all-cause mortality association calibrated Clinical outcome Comparative conducted confidence interval COVID-19 COVID-19 disease database Epidemiology estimate evaluate hazard ratio Hospitalization incidence inhibitor Intensive Intervention lower risk negative control outcome outcomes patients patients with COVID-19 pharmacovigilance PPI propensity score matching receptor Respiratory disease respiratory intervention Result retrospective cohort study Retrospective studies risk risk of COVID-19 secondary outcome significantly South Korea supplementary material tested used data were used [DOI] 10.1186/s40360-022-00549-7 PMC 바로가기 [Article Type] Research
Associations of Nutritional Behavior and Gut Microbiota with the Risk of COVID-19 in Healthy Young Adults in PolandArticle Published on 2022-01-142022-10-31 Journal: Nutrients [Category] COVID-19, SARS, [키워드] age association average Behavior body composition consequence coronavirus disease COVID-19 COVID-19 pandemic Dietary Inflammatory Index dietary intake disease Effect effective evaluate facilitate gut microbiota Health healthy immune function Intervention lack lower risk Minerals nutrition outcome pandemic physical activity physically Poland reduce risk factor risk of COVID-19 SARS-COV-2 infection Vitamin [DOI] 10.3390/nu14020350 PMC 바로가기 [Article Type] Article