moderate disease – Page 10 – Communicable Diseases Research

K18-hACE2 mice develop respiratory disease resembling severe COVID-19

K18-hACE2 쥐, 심각한 COVID-19와 유사한 호흡기 질환 발병

Research Article

Published on 2021-01-192022-08-13
Journal: PLoS Pathogens [Category] COVID-19, Medicine and Health Sciences,

Diarylureas: Repositioning from Antitumor to Antimicrobials or Multi-Target Agents against New Pandemics

Review

Published on 2021-01-192022-10-27
Journal: Antibiotics [Category] COVID-19,

High Prevalence of Hypocalcemia in Non-severe COVID-19 Patients: A Retrospective Case-Control Study

Medicine

Published on 2021-01-072022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

[키워드] 1:1 25-hydroxyvitamin D Admission age albumin albumin level Analysis biochemical parameter bone C-reactive protein calcium Care case-control study Cohort Control controls correlation COVID-19 COVID-19 patient CRP diagnosed discharged disease exclusion Final groups healthy healthy control Hypocalcemia Hypothesis hypovitaminosis Hypovitaminosis D intrinsic medical record Mild moderate disease p value pathophysiological mechanisms Patient patients performed phosphate prevalent Prospective required retrieved retrospective serum serum 25-hydroxyvitamin D serum calcium Sex statistically significant the disease urban Vitamin D Vitamin D supplementation
[DOI] 10.3389/fmed.2020.590805 PMC 바로가기 [Article Type] Medicine

Hydroxychloroquine is associated with slower viral clearance in clinical COVID-19 patients with mild to moderate disease

하이드록시클로로퀸은 경증에서 중등도 질환을 앓고 있는 임상 COVID-19 환자에서 더 느린 바이러스 제거와 관련이 있습니다.

Article

Published on 2020-12-242022-09-11
Journal: Medicine [Category] SARS, 치료제,

[키워드] 24 hour 24 hours 95% confidence interval adjust antiviral drugs Comorbidities confounder COVID-19 COVID-19 patient Cox proportional hazard defined Efficacy Efficacy and safety followed by hazard ratio HCQ hospitalized patients Hydroxychloroquine Linear regression analysis Mild mild to moderate mild to moderate disease moderate disease Multiple multiple linear regression analysis multivariable nasopharyngeal Nasopharyngeal swab negativity oxygen Oxygen therapy Patient Pneumonia positive Primary outcome randomized clinical trial receive regression analysis RT-PCR assay SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral significantly Symptoms tested Treatment turn use of hydroxychloroquine Viral viral clearance was used
[DOI] 10.1097/MD.0000000000023720 PMC 바로가기 [Article Type] Article

Assessment of Maternal and Neonatal SARS-CoV-2 Viral Load, Transplacental Antibody Transfer, and Placental Pathology in Pregnancies During the COVID-19 Pandemic

COVID-19 팬데믹 기간 동안 임산부 및 신생아 SARS-CoV-2 바이러스 부하, Transplacental Antibody Transfer 및 태반 병리 평가

Research

Published on 2020-12-222022-09-10
Journal: JAMA Network Open [Category] MERS, SARS, 진단, 치료기술, 치료법,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus age Analysis angiotensin angiotensin-converting enzyme 2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibody antibody transfer assessment Asymptomatic binding domain biofluids Biological Blood Boston Care Chain Reaction Characteristics cohort study Colocalization Compromised conducted Cord blood coronavirus COVID-19 Critical disease defined detectable disease distribution enrolled enzyme Evidence evidence of exposure expression of SARS-CoV-2 fetoplacental finding Follow-up Immunity implication Importance incidence inefficient Infection Influenza load Massachusetts Maternal maternal plasma measure mechanism Mild Mild disease moderate disease Nasopharyngeal swab Neonatal Neonate Neonates no evidence of nucleocapsid objective occurred outcome participant pathology Placenta placental Placental infection Placentas plasma Point positive pregnancies Pregnancy pregnant women presenting prospective cohort study protective mechanism protective mechanisms provided quantification quantified receptor recruited reduced Relevance respiratory respiratory fluid Result risk robust RT-PCR SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 receptor SARS-CoV-2 RNA SARS-CoV-2 viral load Serine setting severe disease significantly lower tertiary care center tested transfer transmembrane serine protease transmembrane serine protease 2 Transmission transmission of SARS-CoV-2 Transplacental transplacental passage umbilical Umbilical cord underlie vertical transmission Viral Viral load Viremia women
[DOI] 10.1001/jamanetworkopen.2020.30455 PMC 바로가기 [Article Type] Research

Clinical Outcomes, Costs, and Cost-effectiveness of Strategies for Adults Experiencing Sheltered Homelessness During the COVID-19 Pandemic

COVID-19 팬데믹 기간 동안 보호된 노숙자를 경험하는 성인을 위한 전략의 임상 결과, 비용 및 비용 효율성

Research

Published on 2020-12-222022-09-12
Journal: JAMA Network Open [Category] MERS, SARS, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adding age Boston Care Chain Reaction Characteristics clinical Clinical outcome clinical outcomes Cohort cohort characteristics coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Daily decrease Disease progression effective Efficacy Epidemic Epidemics examined exposure finding Health Health care high risk Homeless shelters homelessness Importance individual Infection Intervention management Massachusetts measure Mild mild to moderate moderate Moderate COVID-19 moderate disease National objective outcome participant PCR PCR testing Perspective Point polymerase chain polymerase chain reaction positive positive symptom prevented Program progression reduced reducing Relevance Reproduction number respiratory Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections sensitivity of PCR setting severe acute respiratory syndrome Coronavirus Strategy Symptom temporary The United States Transmission United States
[DOI] 10.1001/jamanetworkopen.2020.28195 PMC 바로가기 [Article Type] Research

Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19

Multi-Omics는 경증과 중등도의 COVID-19 사이의 급격한 질병 상태 변화를 해결합니다

Clinical Trial

Published on 2020-12-102022-09-11
Journal: Cell [Category] SARS, 유전자 메커니즘, 임상,

Correlation Between the COVID-19 Respiratory Triage Score and SARS-COV-2 PCR Test

Medicine

Published on 2020-12-072022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

[키워드] adjusted all subjects Atypical Care CDC Characteristics clinical cough COVID-19 COVID-19 patient cut-off value determine diagnostic Factor Fever healthcare worker identify IMPROVE include individual limit Male sex moderate disease multivariate regression analysis Nasopharyngeal swab nausea non-specific Patient PCR PCR test PCR testing positive positive COVID-19 Positive predictive value predict predicted predictor provided reported required respiratory respiratory symptom respiratory triage retrospective risk ROC SARS-CoV-2 score screened screening for COVID-19 sensitivity Sensitivity and specificity severity specificity Spread subject Surveillance Symptom Symptoms Test tested the disease their family member Triage Viral pneumonia vomiting was done was measured were measured
[DOI] 10.3389/fmed.2020.605689 PMC 바로가기 [Article Type] Medicine

A review of chest radiographic patterns in mild to moderate novel corona virus disease 2019 at an urban hospital in Ghana

2019년 가나 도시 병원에서 발생한 경증에서 중등도의 신종 코로나바이러스 질환의 흉부 방사선 패턴 검토

Original Article

Published on 2020-12-012022-09-10
Journal: Ghana Medical Journal [Category] MERS, SARS, 진단, 치료기술,

[키워드] abnormality affected age association change Characteristics Chest chest imaging Chest radiograph chest radiographic chest radiographs Chest radiography chest X-ray Comorbidities Comorbidity conducted consolidation cough COVID-19 COVID-19 pneumonia diagnosed disease drug Dyspnoea Early detection East evaluated fatigue feature Features Fever funding Gender GGO Ghana ground glass opacities Ground glass opacity hospital imaging modality individual individuals Isolation lung management Mild mild to moderate mild to moderate disease moderate moderate disease MOST Municipal Hospital novel corona virus Patient Patient management Pneumonia Radiographic recorded respiratory Result Retrospective study RT-PCR Symptom symptom status symptomatic and asymptomatic the patient transmitted Vaccine Virus Disease Wuhan Wuhan, China
[DOI] 10.4314/gmj.v54i4s.8 PMC 바로가기 [Article Type] Original Article

Novel serological biomarkers for inflammation in predicting disease severity in patients with COVID-19

COVID-19 환자의 질병 중증도를 예측하는 염증에 대한 새로운 혈청학적 바이오마커

Article

Published on 2020-12-012022-09-11
Journal: International immunopharmacology [Category] SARS, 바이오마커,

[키워드] acute respiratory distress albumin Analysis analyzed biochemical Biomarker C-index C-reactive protein characteristic Coagulation coagulation dysfunction coronavirus disease Coronavirus disease 2019 correlated correlation COVID-19 determine develop diagnostic disease severity elevated Factor fibrinogen groups high mortality High sensitivity C-reactive protein-albumin ratio High sensitivity C-reactive protein-prealbumin ratio Hospital stay identify Inflammation laboratory data Lactate lactate dehydrogenase Logistic regression lymphocyte Lymphocytes Mild mild to moderate moderate disease multivariate logistic regression neutrophil Neutrophils nomogram novel Organ failure parameter Patient patients with COVID-19 Platelet poor prognosis prognostic prognostic biomarker Prognostic biomarkers Prognostic nutritional index receiver operating characteristic reduced respiratory distress risk sensitivity serological severe coronavirus disease severe disease severity severity of COVID-19 Spearman systemic immune-inflammation index urea was used Wuhan
[DOI] 10.1016/j.intimp.2020.107065 PMC 바로가기 [Article Type] Article