A propensity score-matched analysis of mortality in solid organ transplant patients with COVID-19 compared to non-solid organ transplant patients비고형 장기 이식 환자와 비교한 COVID-19 고형 장기 이식 환자의 사망률에 대한 성향 점수 일치 분석Research Article Published on 2021-03-032022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, SARS, [키워드] Admission age Analysis C-reactive protein Clinical characteristics Clinical outcome clinical outcomes Cohort COVID-19 COVID-19 diagnosis COVID-19 pandemic COVID-19 pneumonia creatinine Epidemiology evaluated hospitalized patient ICU intensive care unit kidney liver median time Mortality no significant difference no significant differences non-transplant patients Older age on admission Organ transplant outcome outcomes Patient patients patients died patients with COVID-19 Pneumonia recipient recipients required risk factor Risk factors SARS-COV-2 infection serum creatinine solid organ solid organ transplant SOT transplantation transplants with COVID-19 [DOI] 10.1371/journal.pone.0247251 PMC 바로가기 [Article Type] Research Article
Serum β 2 -microglobulin levels in Coronavirus disease 2019 (Covid-19): Another prognosticator of disease severity?코로나바이러스 질병 2019(Covid-19)의 혈청 β 2 -마이크로글로불린 수준: 질병 중증도의 또 다른 예후 인자?Observational Study Published on 2021-03-012022-09-10 Journal: PLoS ONE [Category] 바이오마커, 임상, [키워드] accompanied Admission age ANOVA test Arabian Peninsula Care circulation Cohort confirmation conformation Control controls coronavirus disease Coronavirus disease 2019 disease disease severity disorder domain elevated Ethnicity etiology FIVE hospital Increases increases in infected with SARS-CoV-2 kDa limitation linear MHC MHC class MHC class I microglobulin Mild Mild disease moderate disease on admission outcome Pathogenesis Patient predict Protein protein complex Sample size Saudi Arabia severe COVID-19 severe disease severity Severity of disease Shed single-center study the major histocompatibility uninfected Viral viral infections were measured WHO [DOI] 10.1371/journal.pone.0247758 PMC 바로가기 [Article Type] Observational Study
COVID-19 in people living with HIV: Clinical implications of dynamics of the immune response to SARS-CoV-2HIV 감염자의 COVID-19: SARS-CoV-2에 대한 면역 반응 역학의 임상적 의미Article Published on 2021-03-012022-09-11 Journal: Journal of medical virology [Category] SARS, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Admission antiretroviral drugs Antiretroviral therapy CD4+ Cellular immune response clinical clinical picture coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cytokine Cytokines disease severity dysregulation elicited Evidence evidence of FIVE greater highest HIV HIV infection HIV patients immune activation immune response Immunoglobulin Immunoglobulin G immunological Immunosuppression implication increased risk Inflammatory maximum Mild Nasopharyngeal swab nasopharyngeal swabs Neutralizing antibodies neutralizing antibody occurred on admission Patient patients PLWH Pneumonia Proinflammatory cytokine proinflammatory cytokines protective role reported respiratory Respiratory failure RNA SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity of COVID-19 T-cell activation two patients Viral viral clearance with COVID-19 with HIV [DOI] 10.1002/jmv.26556 PMC 바로가기 [Article Type] Article
Severe Acute Respiratory Syndrome Coronavirus 2 Clinical Syndromes and Predictors of Disease Severity in Hospitalized Children and Youth중증 급성 호흡기 증후군 코로나 바이러스 2 입원 아동 및 청소년의 질병 중증도의 임상 증후군 및 예측 인자Multicenter Study Published on 2021-03-012022-09-11 Journal: The Journal of pediatrics [Category] 바이오마커, [키워드] 95% CI Absolute lymphocyte count acute respiratory syndrome acute respiratory syndrome coronavirus acute SARS-CoV-2 infection Admission Biomarkers C-reactive protein children clinical clinical feature Clinical features Clinical management conducted Connecticut coronavirus coronavirus 2 COVID-19 decrease died disease manifestation disease severity Fever greater group help Hospital admission Hospitalization Hospitalized hospitalized patient hypoxia identify implication increase in Inflammatory intensive care intensive care unit Lower lymphocyte manifestation MIS-C multicenter multivariable analyses New New York obesity on admission Patient pediatric Pediatric patient Pediatric patients predict Predictive prognostic Prospective Study respiratory Respiratory disease retrospective SARS-CoV-2 SARS-CoV-2 disease SARS-COV-2 infection SARS-CoV-2 infections severe respiratory disease severe SARS severe SARS-CoV-2 socioeconomic status syndrome unit variable Youth [DOI] 10.1016/j.jpeds.2020.11.016 PMC 바로가기 [Article Type] Multicenter Study
Clinical features and risk factors of COVID-19-associated liver injury and function: A retrospective analysis of 830 cases코로나19 관련 간 손상의 임상적 특징과 위험인자 및 기능: 830건의 후향적 분석Article Published on 2021-03-012022-09-11 Journal: Annals of hepatology [Category] MERS, SARS, 바이오마커, [키워드] 95% confidence interval abnormality Admission aims Alanine Alanine transaminase ALT Analysis aspartate Aspartate transaminase AST AST/ALT Betacoronavirus Biochemistry C-reactive protein C-reactive protein (CRP Causality change clinical Clinical features Cohort comparison Computed tomography COVID-19 patients CRP level CRP levels demographic determine Diagnostic Criteria drug Drug induced liver injury elevated exhibited Factor feature groups hepatic Hepatic insufficiency hospitalized COVID-19 patient hospitalized COVID-19 patients incidence information Laboratory testing liver Liver injury lymphocyte multivariable logistic regression Multivariable regression Odds ratio on admission outcome parameter Patient performed Pneumonia potential risk proportion ranged Retrospective analysis risk factor Risk factors tomography Triglyceride was used were used X-ray [DOI] 10.1016/j.aohep.2020.09.011 PMC 바로가기 [Article Type] Article
Increased sCD163 and sCD14 Plasmatic Levels and Depletion of Peripheral Blood Pro-Inflammatory Monocytes, Myeloid and Plasmacytoid Dendritic Cells in Patients With Severe COVID-19 Pneumonia중증 COVID-19 폐렴 환자에서 sCD163 및 sCD14 혈장 수준 증가 및 말초 혈액 염증 유발 단핵구, 골수성 및 형질세포양 수지상 세포 고갈Comparative Study Published on 2021-02-262022-08-31 Journal: Frontiers in Immunology [Category] MERS, 바이오마커, [키워드] Activation Admission ARDS CD163 circulating Clinical outcome clinical utility correlation correlations COVID-19 COVID-19 pneumonia cut-off D-dimer DCs dendritic cell dendritic cells Depletion disease severity early stage ELISA Evidence ferritin flow cytometry greater groups healthy donor healthy donors Hospital admission IL-6 immune cells increase in Increased Inflammatory marker Innate immune cells intermediate monocytes LDH Level marker mDC mDCs monocyte Monocytes myeloid non-classical monocyte Non-classical monocytes on admission patients with COVID-19 pDC pDCs percentage peripheral Peripheral blood peripheral blood monocytes plasmacytoid DC plasmacytoid DCs Pneumonia positive correlation Predictive progression Result risk SARS-CoV-2 sensitivity severity of COVID-19 specificity subject subjects subset the disease [DOI] 10.3389/fimmu.2021.627548 PMC 바로가기 [Article Type] Comparative Study
Serum glucose, lactate dehydrogenase and hypertension are mediators of the effect of body mass index on severity of COVID‐19혈청 포도당, 젖산 탈수소 효소 및 고혈압은 COVID-19의 중증도에 대한 체질량 지수 효과의 매개체입니다Original Research Article Published on 2021-02-162022-09-11 Journal: Endocrinology, Diabetes & Metabolism [Category] MERS, 바이오마커, [키워드] Admission biochemical marker biochemical markers BMI body mass body mass index carried clinical correlations COVID‐19 COVID‐19 CRP determine discharge disease severity Factor form Formal Glucose glycemia Hospitalization Hospitalized hypertension investigated lactate dehydrogenase Lactose LDH less Logistic regression marker Mediation analysis Mild on admission proportion respiratory distress Result Risk factors ROC analysis serum serum markers severity standard deviations systemic inflammation was used [DOI] 10.1002/edm2.215 PMC 바로가기 [Article Type] Original Research Article
Clinical characteristics and outcomes of critically ill COVID-19 patients in Tokyo: a single-center observational study from the first wave도쿄의 중환자 COVID-19 환자의 임상 특성 및 결과: 첫 번째 물결의 단일 센터 관찰 연구Observational Study Published on 2021-02-092022-09-10 Journal: BMC Infectious Diseases [Category] MERS, 임상, 치료제, [키워드] Admission age analyzed center characteristic Characteristics clinical Clinical course clinically coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critically ill Day death died discharged early phase elevated extracorporeal membrane oxygenation Favipiravir First wave High dose Hospital stay ICU In-hospital death Inflammatory intensive care intensive care unit Intubated investigated Japan Japanese Laboratory laboratory finding laboratory findings Laboratory-confirmed COVID-19 lymphocyte majority male marker mechanical ventilation median median age Methylprednisolone Mortality neutrophil Neutrophil-to-lymphocyte ratio observational study on admission one patient outcome oxygen oxygen supplementation pandemic Patient patients peaked receiving reflected Result retrospective single-center Steroids survival survivor Systemic steroid systemic steroids Tokyo tracheostomy trend two patients Ventilation ventilator was performed was used [DOI] 10.1186/s12879-021-05840-2 PMC 바로가기 [Article Type] Observational Study
Acute kidney injury in patients with severe COVID-19 in Mexico멕시코에서 중증 COVID-19 환자의 급성 신장 손상Research Article Published on 2021-02-082022-09-10 Journal: PLoS ONE [Category] MERS, 바이오마커, [키워드] 95% CI Acute kidney injury Admission AKI AUC Care caused Clinical and laboratory data Clinical characteristics cohort of patient Comorbidities COVID-19 COVID-19 pneumonia demographic described disease event Factor FST furosemide Hospital mortality Hospitalization Hospitalized identify IMV in-hospital mortality individual information Invasive mechanical ventilation Kidney injury laboratory data medical record medical records Mortality obesity Older age on admission Patient patients with AKI patients with COVID-19 Pneumonia predict Predictive progressed progression Result risk factor Risk factors ROC Curve SARS-CoV-2 SARS-COV-2 infection sensitivity severe COVID-19 severe pneumonia significantly higher specificity Stage stage 2 Stress stress test systemic disease vasoactive drug vasoactive drugs were recorded [DOI] 10.1371/journal.pone.0246595 PMC 바로가기 [Article Type] Research Article
Point-of-Care Lung Ultrasound for COVID-19: Findings and Prognostic Implications From 105 Consecutive PatientsCOVID-19에 대한 현장 진료 폐 초음파: 105명의 연속 환자로부터 발견 및 예후적 의미Observational Study Published on 2021-02-042022-09-10 Journal: Journal of Intensive Care Medicine [Category] SARS, 임상, 치료기술, [키워드] 24 hour 24 hours Abnormalities abnormality Admission Clinical outcome consolidation consolidations coronavirus COVID-19 death enrolled evaluated finding Hospitalization Hospitalized ICU Intensive intensive care intensive care unit internal medicine large cohort lung Lung ultrasound median Most patient Most patients Negative predictive value non-ICU observational study on admission participant Participants patients with COVID-19 point-of-care Point-of-Care ultrasound Predictive value Prognostic value prospective observational study respiratory Respiratory Support risk stratification tertiary care centers The United States Ultrasound United States Viral pneumonia was performed were assessed with COVID-19 zone [DOI] 10.1177/0885066620988831 PMC 바로가기 [Article Type] Observational Study