A Battle against COVID-19: Vaccine Hesitancy and Awareness with a Comparative Study between Sinopharm and AstraZenecaArticle Published on 2022-02-152022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] adverse effect AstraZeneca Awareness battle booster chronic respiratory disease Comparative complications conducted Confusion COVID-19 COVID-19 infection COVID-19 vaccination cross-sectional demonstrated Evidence Hesitancy intensity lack participant Participants question receiving reported safety profile Side effect significantly higher Sinopharm Symptom vaccination Vaccine vaccine administration Vaccines [DOI] 10.3390/vaccines10020292 PMC 바로가기 [Article Type] Article
Multiple Sclerosis Patients and Disease Modifying Therapies: Impact on Immune Responses against COVID-19 and SARS-CoV-2 VaccinationReview Published on 2022-02-112022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] COVID-19 COVID-19 infection DMTs immunopathology Immunosuppression Impact Modifying Multiple multiple sclerosis Patient patients produced response safety profile SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 vaccination sclerosis severity Vaccine vaccine platform [DOI] 10.3390/vaccines10020279 PMC 바로가기 [Article Type] Review
Avian Orthoavulavirus Type-1 as Vaccine Vector against Respiratory Viral Pathogens in Animal and HumanReview Published on 2022-02-082022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Adaptive immune response animal avian orthoavulaviruses type-1 expression feature Genes Genome Host hosts Human humans include lack limitation mammalian mammalian cell mammals membrane mitigations strategies offer pre-existing immunity protocol Recombination respiratory Respiratory pathogens robust safety profile transitioned unique Vaccine vaccine antigen Vaccines vector vectors viral pathogen virus [DOI] 10.3390/vaccines10020259 PMC 바로가기 [Article Type] Review
Intravenous veterinary ivermectin in a COVID-19 patient causing neurotoxicityCase report Published on 2022-02-072022-10-05 Journal: IDCases [Category] 신약개발, [키워드] administration Concentration Confirmed COVID-19 infection Coronavirus disease 2019 COVID-19 COVID-19 patient dose Hospitalization ICU Infection intensive care intravenous Ivermectin neurotoxicity occur Parenteral Patient required safety profile Serious Adverse Event serum subcutaneous injection was determined [DOI] 10.1016/j.idcr.2022.e01446 [Article Type] Case report
Neurological Conditions Following COVID-19 Vaccinations: Chance or Association?Neurology Published on 2022-02-042022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome adverse event Adverse reaction affected astra zeneca covid-19 vaccine biological plausibility Case report case sery causal link cause ChAdOx1 nCoV-19 vaccine chance condition coronavirus Coronavirus disease 2019 COVID 19 COVID-19 COVID-19 vaccine criteria Diagnosis diagnostic workup Epidemiological study first dose Follow-up global pandemic Guillain-barrè syndrome hospital immunization incidence rate individual level management nervous system neurological neurological adverse event Neurological disease neurological side effects Patient Pfizer vaccine Pfizer-BioNTech Pfizer-BioNTech COVID-19 vaccine physician population level presenting symptoms provided reported safety profile SARS-CoV-2 Seizure subsequent syndrome Treatment vaccination Vaccine Vaccine adverse events Vaccine development vaccine side effects Vaccines virus was determined while World Health Organization Wuhan, China [DOI] 10.7759/cureus.21919 PMC 바로가기 [Article Type] Neurology
Lower Serologic Response to COVID-19 mRNA Vaccine in Patients With Inflammatory Bowel Diseases Treated With Anti-TNFα항-TNFα 치료를 받은 염증성 장 질환 환자의 코로나19 mRNA 백신에 대한 혈청학적 반응 감소Observational Study Published on 2022-02-012022-09-11 Journal: Gastroenterology [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술, [키워드] administration adverse event adverse events AEs all subject all subjects Anti-spike anti-spike antibody anti-TNF antibody BNT162b2 booster dose comparable coronavirus disease COVID-19 dose doses drug level drug levels enrolled function functional groups HCs healthy control healthy controls high risk IBD infection rate infections Inflammatory bowel disease inflammatory bowel diseases inhibitory Lower magnitude Messenger RNA mounted mRNA mRNA-BNT162b2. multicenter Necrosis not affect Patient patients treated Pfizer Pfizer/BioNTech Prospective Prospective Study remained response Safe safety profile second dose serologic Serologic response serologic responses seronegative seropositive significantly lower stratified therapy TNFα treated treated patients Treatment Vaccine vaccine dose vaccine response vaccine responses [DOI] 10.1053/j.gastro.2021.10.029 PMC 바로가기 [Article Type] Observational Study
Design and implementation of an international, multi-arm, multi-stage platform master protocol for trials of novel SARS-CoV-2 antiviral agents: Therapeutics for Inpatients with COVID-19 (TICO/ACTIV-3)새로운 SARS-CoV-2 항바이러스제 시험을 위한 국제, 다군, 다단계 플랫폼 마스터 프로토콜의 설계 및 구현: COVID-19 입원 환자를 위한 치료제(TICO/ACTIV-3)Article Published on 2022-02-012022-09-11 Journal: Clinical Trials (London, England) [Category] 임상, 치료제, [키워드] adults hospitalized agent Antiviral Antiviral agents applicability approach approaches approval clinical trial collaboration Consent Forms COVID-19 Data collection drug effective therapy Efficacy enrolled Evidence evidence of expected facilitate feature FIVE food Food and Drug Administration forms harmonization hospitalized patient hospitalized patients implementation infection rate infection rates information initiated Inpatient Inpatients International matching placebo multi-arm multi-arm multi-stage Other outbreak overcome participant participated Patient Placebo platform platform trials. potential therapeutic agent potential therapeutic agents protocol provided Randomized Rapid recruitment Regulatory required robust safety evaluation Safety Monitoring Board safety profile Sample size SARS-CoV-2 Stage subsequent target population therapeutic agent Therapeutics Trial trials with COVID-19 [DOI] 10.1177/17407745211049829 PMC 바로가기 [Article Type] Article
[Translated article] Hydroxychloroquine: An Essential Drug in Dermatology and Its Controversial Use in COVID-19Research article Published on 2022-02-012022-10-05 Journal: Actas Dermo-Sifiliográficas [Category] 치료제, [키워드] adverse effects Anti-inflammatory antimalarial antiviral properties breastfeeding women can be used caused children clinical COVID-19 Dermatology Diseases drug erythematous Essential granuloma Hydroxychloroquine immune system immunomodulatory Lichen planus lupus erythematosus Meta-analysis porphyria pregnant Prevent recent Regular safety profile sarcoidosis SARS-CoV-2 supply shortage Supply shortages suppress therapy treat [DOI] 10.1016/j.ad.2022.01.012 [Article Type] Research article
Third dose of the BNT162b2 vaccine in heart transplant recipients: Immunogenicity and clinical experience심장 이식 환자에게 BNT162b2 백신 3차 접종: 면역원성과 임상 경험Article Published on 2022-02-012022-09-12 Journal: The Journal of heart and lung transplantation : th [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] adverse events anti-RBD Anti-RBD antibody BNT162b2 BNT162b2 vaccine booster booster dose C-reactive protein cellular immune responses clinical experience Cohort COVID-19 COVID-19 pandemic defined domain dose elicited Heart transplantation homologous humoral IgG IgG anti-RBD immune response Immunocompromised immunogenicity increase in injection investigated likelihood majority Mild mycophenolate Neutralizing antibodies neutralizing antibody neutralizing capacity Pain Patient patients Pfizer populations positive antibody response primary doses RBD recipients reduced rejection repeated safety profile SARS-CoV-2 neutralization second dose Serious Adverse Event Specific T-cell response subset T cell response the vaccine Tolerability vaccine response vaccine-induced antibody response were assessed were recorded [DOI] 10.1016/j.healun.2021.08.010 PMC 바로가기 [Article Type] Article
Phytomelatonin: a potential phytotherapeutic intervention on COVID-19-exposed individuals피토멜라토닌: COVID-19에 노출된 개인에 대한 잠재적 식물 치료 개입Review Published on 2022-02-012022-09-11 Journal: Microbes and infection [Category] COVID19(2023년), SARS, 치료기술, [키워드] acting advancement Anti-inflammatory antioxidant antioxidant effects biological processe blood-brain barrier body temperature Cancer Cell content convenience COVID-19 COVID-19-exposed individuals cross Enzymes extraction free radical immunological individual individuals Intervention involved mitochondrial mood swings pathway physiological Phytomelatonin Phytotherapeutic. plant Plant hormone pleiotropic pro-inflammatory signaling radical scavenger reducing Regulation respiratory infections safety profile Sleep suggested swings therapeutic potential up-regulating [DOI] 10.1016/j.micinf.2021.104886 PMC 바로가기 [Article Type] Review