CRISPR/Cas9-mediated gene knockout screens and target identification via whole-genome sequencing uncover host genes required for picornavirus infectionCRISPR/Cas9 매개 유전자 녹아웃 스크리닝 및 전체 유전체 시퀀싱을 통한 표적 식별이 피코르나바이러스 감염에 필요한 숙주 유전자를 밝혀냅니다.Article Published on 2017-06-232024-08-01 Journal: Brain stimulation [Category] 폴리오, [키워드] CRISPR screen CRISPR/Cas Enterovirus D68 host-pathogen interaction Poliovirus RNA virus sialic acid whole-genome sequencing [DOI] 10.1074/jbc.M117.782425 PMC 바로가기
Synthesis and In Vitro Anti-Influenza Virus Evaluation of Novel Sialic Acid (C-5 and C-9)-Pentacyclic Triterpene Derivatives †Article Published on 2017-06-222023-06-08 Journal: Molecules [Category] 신종인플루엔자, [키워드] Influenza virus pentacyclic triterpene sialic acid Structure-activity relationship (SAR) [DOI] 10.3390/molecules22071018 PMC 바로가기 [Article Type] Article
Receptor specificity of subtype H1 influenza A viruses isolated from swine and humans in the United StatesArticle Published on 2017-04-182023-06-23 Journal: Virology [Category] 신종인플루엔자, [키워드] binding H1 hemagglutinin Human Influenza receptor sialic acid swine [DOI] 10.1016/j.virol.2011.01.015 PMC 바로가기 [Article Type] Article
Edible bird’s nest modulate intracellular molecular pathways of influenza A virus infected cellsResearch Article Published on 2017-01-052023-05-23 Journal: BMC Complementary and Alternative Medicine [Category] Fulltext, 신종인플루엔자, [키워드] Antiviral autophagy Edible bird nest (EBN) endosome trafficking Immunoflourescent influenza A virus sialic acid [DOI] 10.1186/s12906-016-1498-x PMC 바로가기 [Article Type] Research Article
Abiotic stress of ambient cold temperature regulates the host receptivity to pathogens by cell surfaced sialic acidsArticle Published on 2016-07-292023-06-24 Journal: Biochemical and Biophysical Research Communication [Category] 신종인플루엔자, [키워드] Cold temperature hemagglutinin receptivity sialic acid Sialyltransferase virus [DOI] 10.1016/j.bbrc.2016.05.020
Cellular entry of the porcine epidemic diarrhea virusArticle Published on 2016-06-152022-11-01 Journal: Virus research [Category] Coronavirus, MERS, [키워드] Americas aminopeptidase N Asia binding binding activity carbohydrate Cell coronavirus Culture determine diarrhea domain East epidemic diarrhea epithelial cell Factor functional glycoprotein host cell in vitro in vivo Infection initial Interaction medium membrane fusion N-terminal observation outbreak PED PEDV Porcine epidemic diarrhea virus protease Protein proteolytic activation receptor receptor interaction replicate reported resulting S protein S proteins sialic acid Sialic acid binding small intestine spike subsequent target cell the S protein tissue tropism trimer villus virus virus entry virus infection virus tropism [DOI] 10.1016/j.virusres.2016.05.031 PMC 바로가기 [Article Type] Article
Streptococcus pneumoniae NanC STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR스트렙토코쿠스 뉴모니에 NanC 특정성과 시알리다제 억제제를 생성하는 시알리다제의 메커니즘에 대한 구조적 통찰Article Published on 2015-11-132024-08-04 Journal: Brain stimulation [Category] 폐렴구균 감염증, [키워드] Carbohydrate-binding module glycoside hydrolase NanC neu5ac2en neuraminidase pneumococcus sialic acid sialidase Streptococcus [DOI] 10.1074/jbc.M115.673632 PMC 바로가기
Sialic Acids on Varicella-Zoster Virus Glycoprotein B Are Required for Cell-Cell FusionArticle Published on 2015-08-072023-06-01 Journal: The Journal of Biological Chemistry [Category] 두창, 수두, 홍역, [키워드] herpesvirus membrane fusion myelin-associated glycoprotein (MAG) N-linked glycosylation O-linked glycosylation sialic acid sialic acid-binding immunoglobulin-type lectin 4 (Siglec-4) Varicella-zoster virus (VZV) virus entry [DOI] 10.1074/jbc.M114.635508 PMC 바로가기
Host Tissue and Glycan Binding Specificities of Avian Viral Attachment Proteins Using Novel Avian Tissue MicroarraysResearch Article Published on 2015-06-022022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] attachment attachment protein binding binding pattern Coronaviral coronavirus CoV Critical dependent on glycan Host host cell hosts Infectious disease influenza virus H5N1 initial Interaction lung M41 Microarray novel organ organ system pathogen Pathogens platform predominant profile Protein reported respiratory tissue S1 protein selected sialic acid specificity susceptibility susceptible tissue tissues type I Validity virus [DOI] 10.1371/journal.pone.0128893 PMC 바로가기 [Article Type] Research Article
Severity of Influenza A(H1N1) Illness and Emergence of D225G Variant, 2013–14 Influenza Season, Florida, USAArticle Published on 2015-04-012023-06-08 Journal: Emerging Infectious Diseases [Category] Fulltext, 신종인플루엔자, [키워드] acute respiratory distress syndrome D225G polymorphism Florida Genetic changes H1N1 subtype hemagglutinin Influenza Influenza virus pandemic Respiratory tract disease sialic acid viruses [DOI] 10.3201/eid2104.141375 PMC 바로가기