Comparative Proteome Analysis of Porcine Jejunum Tissues in Response to a Virulent Strain of Porcine Epidemic Diarrhea Virus and Its Attenuated StrainArticle Published on 2016-11-292022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Analysis Attenuated carried change Comparative diarrhea epidemic diarrhea eukaryotic expressed groups Heat shock heterogeneous immune system Infection inoculated Interaction interferon-stimulated gene involved ISGs iTRAQ Jejunum labeling Laboratory mechanism Mortality nuclear organ Pathogenesis pathogenicity PEDV Porcine epidemic diarrhea virus predominant produced Protein proteomic quantitation quantitative proteome analysis response responses responsible ribonucleoprotein Signal transduction strain Strains Stress tissue up-regulated virulent virus [DOI] 10.3390/v8120323 PMC 바로가기 [Article Type] Article
Characterization of pneumococcal Ser/Thr protein phosphatase phpP mutant and identification of a novel PhpP substrate, putative RNA binding protein Jag폐렴구균 Ser/Thr 단백질 인산가수분해효소 phpP 돌연변이의 특성화 및 새로운 PhpP 기질, 추정 RNA 결합 단백질 Jag의 확인Research Article Published on 2016-10-242024-08-01 Journal: BMC Microbiology [Category] 폐렴구균 감염증, [키워드] cell division Jag Phosphorylation protein kinase Protein phosphatase Signal transduction Streptococcus [DOI] 10.1186/s12866-016-0865-6 PMC 바로가기 [Article Type] Research Article
The Anti-sigma Factor RsiV Is a Bacterial Receptor for Lysozyme: Co-crystal Structure Determination and Demonstration That Binding of Lysozyme to RsiV Is Required for σ V Activation항-시그마 인자 RsiV는 리소자임에 대한 박테리아 수용체입니다: 공결정 구조 결정 및 RsiV에 대한 라이소자임의 결합이 σ V 활성화에 필요하다는 입증Research Article Published on 2016-09-072022-09-17 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence acting activate activated Activation active site addition Bacteria Bacterial bind binding cascade Cell cell wall cleavage cleave complex crystal structure Defense demonstrated demonstration Determination enzymatic activity enzyme Evidence Factor function functions Gram-positive bacteria inhibit inhibitor initiated innate immune lysozyme many case mutant promoter protease Proteases Protein proteolytic receptor regulated required resistance mechanisms RIP RNA polymerase sensor signal Signal transduction specificity Structure suggested susceptible Target genes the cell These data thought Trigger triggering triggers X-ray [DOI] 10.1371/journal.pgen.1006287 PMC 바로가기 [Article Type] Research Article
Implications of Spatiotemporal Regulation of Shigella flexneri Type Three Secretion Activity on Effector Functions: Think Globally, Act Locally시겔라 플렉스네리 3형 분비 활성을 시공간적으로 조절하는 것의 효과 기능에 대한 함의: 글로벌하게 생각하고, 로컬하게 행동하라Review Published on 2016-03-092024-07-30 Journal: Frontiers in Cellular and Infection Microbiology [Category] 세균성이질, [키워드] effectors Enteropathogens host-pathogen interactions Shigella Signal transduction type three secretion apparatus type three secretion system [DOI] 10.3389/fcimb.2016.00028 PMC 바로가기 [Article Type] Review
Acidic pH and divalent cation sensing by PhoQ are dispensable for systemic salmonellae virulence산성 pH와 이가 양이온 감지는 시스템성 살모넬라 virulence에 필요하지 않다.Article Published on 2015-05-232024-07-30 Journal: eLife [Category] 살모넬라증, [키워드] Bacterial pathogenesis Innate immunity intracellular virulence Other Salmonella sensor kinase Signal transduction [DOI] 10.7554/eLife.06792 PMC 바로가기
Influenza, a One Health paradigm–novel therapeutic strategies to fight a zoonotic pathogen with pandemic potentialReview Published on 2014-10-012023-06-02 Journal: International journal of medical microbiology : IJMM [Category] 조류인플루엔자, [키워드] antiviral therapy immune modulation Influenza virus one health Polymerase complex Signal transduction [DOI] 10.1016/j.ijmm.2014.08.016 [Article Type] Review
PRO40 Is a Scaffold Protein of the Cell Wall Integrity Pathway, Linking the MAP Kinase Module to the Upstream Activator Protein Kinase CPRO40은 MAP 키나제 모듈을 업스트림 활성제 단백질 키나제 C에 연결하는 세포벽 무결성 경로의 스캐폴드 단백질입니다.Research Article Published on 2014-09-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activator adapter adapters Affinity purification Alzheimer's disease approach ascomycete asexual development bind Cancer Cell cell differentiation Cell fusion cell wall characterized combating conserved Control deletion mutant deletion mutants determinant developmental developmental processe developmental processes disease domain ENCODE environmental cue environmental cues eukaryote eukaryotes eukaryotic Evidence experiment Extensive filamentous fungi fruiting bodies fungal fungi fungus Genetic growth homolog implicated integrity Interaction interaction partner involved kinase MAPK mass spectrometry mitogen mitogen-activated protein kinase module molecular MOST mutant mutated N-terminal Pathogenesis pathogenicity pathway Pathways Phosphorylation polar Protein protein kinase protein kinase C Regulation required scaffold protein Signal transduction Signaling Sordaria macrospora Stress stress response symbiosis the cell upstream vegetative growth wall yeast [DOI] 10.1371/journal.pgen.1004582 PMC 바로가기 [Article Type] Research Article
Interleukin-1 receptor-associated kinase-2 genetic variant rs708035 increases NF-κB activity through promoting TRAF6 ubiquitinationArticle Published on 2014-05-022023-06-25 Journal: The Journal of Biological Chemistry [Category] 신종인플루엔자, [키워드] Cell Biology Gene regulation Inflammation Signal transduction toll-like receptors (TLR) [DOI] 10.1074/jbc.M113.538009 PMC 바로가기
Transcriptome analysis of chicken kidney tissues following coronavirus avian infectious bronchitis virus infectionResearch Article Published on 2013-10-302022-10-28 Journal: BMC Genomics [Category] Coronavirus, MERS, [키워드] Analysis analyzed Antiviral Apoptosis bronchitis cascade cause Cell compared conducted contagious contributed coronavirus cytokine differential expression differentially expressed gene down-regulated Gene Gene expression profiling Genes Host host defense response Host transcriptional response IBV IBV infection identify IL6 immune immune responses immune-related gene Infection infectious Infectious Bronchitis Virus Inflammatory response innate immune Interaction involved IRF1 KEGG pathway kidney kidney tissue kidney tissues knowledge mechanism Microarray molecular MOST MYD88 NFKB2 Ontology Pathogenesis pathway positive provided real-time RT-PCR Regulation related Result Signal transduction Stat1 the Coronaviridae Transcriptome transcriptome analysis up-regulated upper respiratory tract virus [DOI] 10.1186/1471-2164-14-743 PMC 바로가기 [Article Type] Research Article
Effects of CpG-ODNs on phenotype and function of monocyte-derived dendritic cells in chronic hepatitis BArticle Published on 2011-11-212023-06-15 Journal: World journal of gastroenterology [Category] B형 간염, [키워드] Chronic Hepatitis B CpG oligodeoxynucleotides dendritic cell hepatitis B surface antigen Signal transduction [DOI] 10.3748/wjg.v17.i43.4825 PMC 바로가기