symptomatic infection – Page 10 – Communicable Diseases Research

LB6. Asymptomatic Infection and Duration of Viral Shedding in Symptomatic Breakthrough Infections in a Phase 3 Study of AZD1222 (ChAdOx1 nCoV-19)

Poster Abstracts

Published on 2021-11-042022-10-29
Journal: Open Forum Infectious Diseases [Category] COVID-19,

Symptomatic post-vaccination SARS-CoV-2 infections in healthcare workers- A multicenter cohort study

Observational Study

Published on 2021-11-012022-10-05
Journal: Diabetes & metabolic syndrome [Category] SARS, 임상,

[키워드] 95%CI Apollo break Break through infections Breakthrough infection case-control study clinical clinical parameter Cohort COVID COVID-19 COVID-19 vaccination COVID-19 vaccine death evaluated examined group healthcare healthcare worker Healthcare workers hospital Hospitalization inactivated India Infection infections maximum Mild multicenter cohort study Nursing occurred Occurrence provided recombinant reducing retrospective SARS-CoV-2 SARS-COV-2 infection severe disease severity Sex significant difference significantly lower symptomatic symptomatic infection symptomatic SARS-CoV-2 infection vaccination Vaccine vaccine dose Vaccines Vero Cell virion were given
[DOI] 10.1016/j.dsx.2021.102306 PMC 바로가기 [Article Type] Observational Study

Determinants and Dynamics of SARS-CoV-2 Infection in a Diverse Population: 6-Month Evaluation of a Prospective Cohort Study

다양한 인구에서 SARS-CoV-2 감염의 결정 요인 및 역학: 예비 코호트 연구의 6개월 평가

Observational Study

Published on 2021-10-282022-09-11
Journal: The Journal of Infectious Diseases [Category] MERS, SARS, 임상, 진단, 치료기술,

[키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted odds ratio affected antibodies antibody Asymptomatic asymptomatic infection asymptomatic infections Chain Reaction change Cohort Comorbidities coronavirus correlated COVID-19 determinant Dynamics Dyspnea healthcare worker Healthcare workers hospital humoral Humoral immunity IgG IgG antibodies IgG antibody IgG response IgG responses IgG titer IgG titers Immunoglobulin Immunoglobulin G Increases Infection Longitudinal data longitudinal data analysis magnitude median MOST Multivariable models neurologic Odds ratio participant Participants polymerase chain polymerase chain reaction postacute sequelae of COVID-19 Prolonged Prospective prospective cohort Registration respiratory risk Risk factors SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 polymerase chain reaction severe acute respiratory syndrome Coronavirus severe symptoms Symptom symptom severity symptomatic symptomatic infection symptomatic infections Symptoms tested trajectory
[DOI] 10.1093/infdis/jiab411 PMC 바로가기 [Article Type] Observational Study

Measuring vaccine efficacy against infection and disease in clinical trials: sources and magnitude of bias in COVID-19 vaccine efficacy estimates

임상 시험에서 감염 및 질병에 대한 백신 효능 측정: COVID-19 백신 효능 추정치의 편향 출처 및 규모

Major Article

Published on 2021-10-262022-09-10
Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료기술,

[키워드] Ad26 Ad26.COV2.S antibodies approaches arise Asymptomatic asymptomatic infection asymptomatic infections bias biases breakthrough infections ChAdOx1 changes in Characteristics clinical trial competing COVID-19 COVID-19 vaccine direction disease Effectiveness Efficacy estimate estimates expected implication indicate Infection janssen less magnitude mathematical mathematical model Multiple Oxford-AstraZeneca PCR performed phase Phase III trials Prevent PROTECT Result SARS-CoV-2 Sensitivity and specificity serology serostatus specificity Symptom symptomatic symptomatic and asymptomatic symptomatic infection symptomatic infections the vaccine Trial Vaccine vaccine efficacy Vaccine-induced immunity Vaccines
[DOI] 10.1093/cid/ciab914 PMC 바로가기 [Article Type] Major Article

The potential role of inhaled nitric oxide for postexposure chemoprophylaxis of COVID-19

Short Communications

Published on 2021-10-222022-10-30
Journal: Journal of Genetic Engineering & Biotechnology [Category] COVID-19,

[키워드] abort clinically complications COVID-19 cytosolic decrease groups impair Inhaled morbidity and mortality nitric oxide Prevent Prophylaxis replicate respiratory tract SARS-CoV-2 subsequent symptomatic infection upper respiratory tract Vaccine Viral load
[DOI] 10.1186/s43141-021-00249-5 PMC 바로가기 [Article Type] Short Communications

Innovative clinical trial design and delivery: a phase 3 COVID-19 post-exposure prophylaxis study in skilled nursing and assisted living facilities (BLAZE-2)

혁신적인 임상 시험 설계 및 전달: 전문 간호 및 생활 보조 시설(BLAZE-2)에서 COVID-19 노출 후 예방 연구 3상

Randomized Controlled Trial

Published on 2021-10-212022-09-10
Journal: Trials [Category] MERS, SARS, 임상,

[키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addressed all age groups allergy analytics bamlanivimab BLAZE-2 Care Clinical trial design collaboration Community complications conducted Conducting coronavirus coronavirus disease coronavirus disease-2019 COVID-19 Critical case defined double-blind Efficacy and safety evaluate home care Infectious diseases Lilly LY3819253 monoclonal antibody morbidity morbidity and mortality nursing home Older Older adults pandemic participant Phase 3 Placebo placebo-controlled trial populations Prevalence Prevent Prophylaxis Pulmonary infection randomization Randomized Research respiratory respiratory distress Respiratory distress syndrome Respiratory failure risk SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe and critical cases severe COVID-19 Skilled nursing facilities Spread spread of COVID-19 supplementary material Supply chain Support symptomatic infection syndrome target population Therapeutic strategies therapeutic strategy Travel Trial USA
[DOI] 10.1186/s13063-021-05699-3 PMC 바로가기 [Article Type] Randomized Controlled Trial

Effect of Delta variant on viral burden and vaccine effectiveness against new SARS-CoV-2 infections in the UK

영국의 새로운 SARS-CoV-2 감염에 대한 바이러스 부담 및 백신 효과에 대한 Delta 변이체의 영향

Article

Published on 2021-10-142022-09-10
Journal: Nature Medicine [Category] MERS, SARS, 변종, 진단,

[키워드] (alpha absolute difference acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adults Alpha Alpha variant attenuation B.1.1.7 B.1.617.2 BNT162b2 ChAdOx1 ChAdOx1 vaccine ChAdOx1 vaccines Chain Reaction coronavirus Decline Delta delta variant dominant dose dosing interval Effect Effectiveness Epidemiology Evidence faster greater Immunity increasingly indicate individuals Infection infections initial investigated natural infection new infections new SARS-CoV-2 of BNT162b2 PCR-positive polymerase chain polymerase chain reaction Randomly reduce reduced respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 vaccination second dose selected significantly Symptom symptomatic infection United Kingdom vaccinated individual vaccinated individuals vaccination Vaccine variant Viral viral burden viral infection
[DOI] 10.1038/s41591-021-01548-7 PMC 바로가기 [Article Type] Article

Effectiveness of COVID-19 vaccines against SARS-CoV-2 infection with the Delta (B.1.617.2) variant: second interim results of a living systematic review and meta-analysis, 1 January to 25 August 2021

Delta(B.1.617.2) 변이형 SARS-CoV-2 감염에 대한 COVID-19 백신의 효과: 살아있는 체계적인 검토 및 메타 분석의 두 번째 중간 결과, 2021년 1월 1일부터 8월 25일까지

Meta-Analysis

Published on 2021-10-142022-09-10
Journal: Eurosurveillance [Category] MERS, SARS, 변종,

Assessment of Communication Strategies for Mitigating COVID-19 Vaccine-Specific Hesitancy in Canada

Research

Published on 2021-09-302022-10-29
Journal: JAMA Network Open [Category] COVID-19,

[키워드] age asked assessment assigned AstraZeneca Canada census combating communication conducted COVID-19 COVID-19 infection COVID-19 vaccinations COVID-19 vaccine COVID-19 vaccines death effective Effectiveness Efficacy Ensuring experiment exposure finding Gender Hesitancy Importance IMPROVE individual information Interaction Intervention Johnson & Johnson less likelihood measure median Metrics objective offered Older opposite pandemic participant Perceived Point profiles provided public health communication random assignment Randomly receive reduce Relevance reported respondent Result scaled setting statistically significant Strategy symptomatic symptomatic infection Transmission Treatment Vaccine Vaccines were measured widespread women yes or no
[DOI] 10.1001/jamanetworkopen.2021.26635 PMC 바로가기 [Article Type] Research

Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection

증상 및 무증상 SARS-CoV-2 감염에 대한 보호 상관관계

Article

Published on 2021-09-292022-09-10
Journal: Nature Medicine [Category] MERS, SARS, 변종, 임상, 진단,

[키워드] Alpha analyzed Anti-RBD antibodies Anti-spike antibody antibody levels Antibody Units assays asymptomatic infection asymptomatic infections AZD1222 B.1.1.7 binding binding and neutralizing antibodies binding antibody unit binding antibody units can be used ChAdOx1 ChAdOx1 nCoV-19 correlated COVID-19 vaccine COVID-19 vaccines determine Efficacy elicited estimate extrapolation facilitate immune marker immune markers immune response Infectious diseases International international unit majority marker neutralization neutralization titer neutralization titers Neutralizing antibodies neutralizing antibody normalized not correlated Population Predictive pseudovirus Randomized recipients reduced risk SARS-CoV-2 SARS-COV-2 infection second dose significance level symptomatic and asymptomatic symptomatic infection These data Trial United Kingdom Vaccine vaccine efficacy Vaccines variant of SARS-CoV-2 were measured
[DOI] 10.1038/s41591-021-01540-1 PMC 바로가기 [Article Type] Article