Angiotensin II receptor blocker or angiotensin-converting enzyme inhibitor use and COVID-19-related outcomes among US VeteransResearch Article Published on 2021-04-232022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] 95% confidence interval 95%CI ACEi ACEIs acute respiratory syndrome all-cause hospitalization all-cause mortality analyses Analysis Angiotensin II angiotensin-converting enzyme inhibitor ARB ARBs association blocker Characteristics coronavirus coronavirus disease covariate adjustment COVID-19 Cox regression death deaths exposure group Follow-up hazard ratio Hospitalization Hospitalized hypertension indication Infection Inpatient Inpatients investigated median medication Mortality negative control outcome Outpatient outpatients Patient Primary outcome randomized trials receptor reduce retrospective cohort study SARS-CoV-2 SARS-COV-2 infection Support treated veteran Weighting [DOI] 10.1371/journal.pone.0248080 PMC 바로가기 [Article Type] Research Article
High-dimensional characterization of post-acute sequelae of COVID-19 Research Published on 2021-04-222022-10-05 Journal: Nature [Category] SARS, 치료법, [키워드] acute COVID-19 acute phase Affair Analysis approach Cardiovascular disorders Care clinical manifestation COVID-19 database death Department described diagnoses Diagnosis disease disorders Evidence fatigue Health health system healthcare help higher risk Hospitalized identify include increase individuals with COVID-19 Infection intensive care Laboratory laboratory abnormality malaise medication mental health disorders Metabolic disorders Musculoskeletal National nervous system organ system organ systems Pain Patient patients with COVID-19 people with COVID-19 prespecified outcome reduce resources Respiratory system reveal risk severity survived therapeutic veteran [DOI] 10.1038/s41586-021-03553-9 [Article Type] Research
COVID-19 associated mortality and cardiovascular disease outcomes among US women veteransArticle Published on 2021-04-192022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] 95% CI Affair age antiplatelet baseline BMI body mass index cardiovascular disease cardiovascular event Cardiovascular events Chronic kidney disease chronic obstructive CKD collected condition conducted confidence COPD COVID-19 COVID-19 research Cox proportional hazard CVD death defined diabetes disease distribution Effect Epidemiology Evidence Follow-up Generalized linear model greater groups hazard incidence increased mortality infection rate Infectious diseases interval Kaplan–Meier lower risk Mortality mortality risk National obesity outcome outcomes positive predictor pulmonary disease Ratio Repository retrospective cohort Risk factors SARS-CoV-2 SARS-COV-2 infection smoking status tested Treatment veteran women [DOI] 10.1038/s41598-021-88111-z PMC 바로가기 [Article Type] Article
Association of Symptoms of Posttraumatic Stress Disorder With Posttraumatic Psychological Growth Among US Veterans During the COVID-19 PandemicResearch Published on 2021-04-082022-10-29 Journal: JAMA Network Open [Category] Coronavirus, MERS, SARS, [키워드] association COVID-19 COVID-19 pandemic disorder growth Posttraumatic Stress Psychological PTSD Symptom veteran [DOI] 10.1001/jamanetworkopen.2021.4972 PMC 바로가기 [Article Type] Research
Development of COVIDVax Model to Estimate the Risk of SARS-CoV-2–Related Death Among 7.6 Million US Veterans for Use in Vaccination PrioritizationResearch Published on 2021-04-062022-10-29 Journal: JAMA Network Open [Category] COVID-19, MERS, SARS, [키워드] 95% CI Affair age assessment AUROC baseline characteristics black body mass index Care center characteristic Charlson Comorbidity Index Chronic kidney disease Cohort congestive heart failure Control death defined Department develop development diabetes effective EHR data Electronic health record enrolled estimate exhibited expected Final finding General population Health help Hispanic Immunity Importance individual individuals logistic regression model measure men Model Mortality objective observation period occur participant platform Point positive predicted predictors Prevent prevention prognostic proportion Relevance Result risk risk score SARS-CoV-2 SARS-CoV-2 vaccination setting Sex significantly higher the mean used data vaccination Vaccine veteran white [DOI] 10.1001/jamanetworkopen.2021.4347 PMC 바로가기 [Article Type] Research
The Association Between Alpha-1 Adrenergic Receptor Antagonists and In-Hospital Mortality From COVID-19Medicine Published on 2021-03-312022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI Admission Adrenergic Affair alpha-1-adrenergic receptor antagonist antagonist antagonists association baseline Control coronavirus disease COVID-19 death Department effective etiology Healthcare system Hospitalization hyperinflammation in-hospital mortality independent Infectious disease inhibitor likelihood Odds ratio off-label drug use Patient placebo-controlled clinical trial Randomized receptor receptors reduce mortality reducing mortality retrospective cohort risk reduction robust subset symptomatic infection therapy veteran [DOI] 10.3389/fmed.2021.637647 PMC 바로가기 [Article Type] Medicine
The association of COVID-19 occurrence and severity with the use of angiotensin converting enzyme inhibitors or angiotensin-II receptor blockers in patients with hypertensionResearch Article Published on 2021-03-182022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] 95% CI 95% confidence interval ACEi adjusted Affair age angiotensin-converting enzyme inhibitor ARB association blocker CCI Charlson Comorbidity Index Clinical severity Cohort collected Comorbidities Comorbidity coronavirus disease covariates COVID-19 COVID-19 testing demographics Department determine died enzyme examined Hospitalization Hospitalized hypertension ICU Inconclusive increase in inhibitor Inpatient intensive care investigated Logistic regression mechanical ventilation mechanical ventilator mechanical ventilators medication medications Mortality multinomial logistic regression Occurrence Odds ratio outcome outpatients participant Patient patients positive positive COVID-19 receptor reported Result selected severity severity of COVID-19 Sex significantly significantly increased Sociodemographic veteran veterans warehouse Weighting [DOI] 10.1371/journal.pone.0248652 PMC 바로가기 [Article Type] Research Article
Heterogeneity in COVID-19 patient volume, characteristics and outcomes across US Department of Veterans Affairs facilities: an observational cohort studyObservational Study Published on 2021-03-082022-10-05 Journal: BMJ Open [Category] SARS, 임상, [키워드] accounted adult intensive & Affair age Characteristics cohort study COVID-19 COVID-19 mortality COVID-19 patient COVID-19 testing Critical Critical care Department difference Effect explained Follow-up general medicine (see internal medicine) healthcare facility Healthcare system heterogeneity Hospital admission ICU ICU patient Inpatient Intensive intensive care IQR logistic regression modelling majority mechanical ventilation mechanical ventilator median age Mortality Observational cohort study outcome Patient patients with COVID-19 populations USA Variation veteran Volume with COVID-19 [DOI] 10.1136/bmjopen-2020-044646 PMC 바로가기 [Article Type] Observational Study
Association of mortality and aspirin prescription for COVID-19 patients at the Veterans Health AdministrationResearch Article Published on 2021-02-112022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] 30-Day mortality 95% CI Aspirin Care clinically Cohort common contribute correlation country COVID-19 COVID-19 mortality COVID-19 patient COVID-19 positive patient database decrease decreased mortality demonstrated diagnosed with COVID-19 Evidence finding first positive Health implication inflammatory pathway lab medication mitigate Mortality National overall mortality Pathways Patient Patient care polymerase chain positive pre-diagnosis Prospective required retrospective severity of COVID-19 significant decrease statistically thrombotic veteran veterans [DOI] 10.1371/journal.pone.0246825 PMC 바로가기 [Article Type] Research Article
Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort studyObservational Study Published on 2021-02-112022-10-05 Journal: The BMJ [Category] Fulltext, MERS, 임상, [키워드] 24 hour 95% confidence interval acute respiratory syndrome Admission analyses Analysis anticoagulation association bleeding bleeding events Care Clinical deterioration cohort of patient cohort study coronavirus coronavirus disease cumulative death Department E-value evaluate Evidence hazard ratio Healthcare system hospital Hospital admission Hospital stay incidence increased risk Infection initial Laboratory Mortality MOST National occurred outcome Patient Probability Prophylactic receipt receive receiving required Result risk risk of death robust SARS-CoV-2 secondary Sensitivity analyses Support The United States therapeutic anticoagulation Thromboembolic events treated patient Treatment veteran [DOI] 10.1136/bmj.n311 PMC 바로가기 [Article Type] Observational Study