The SARS-CoV-2-Inactivating Activity of Hydroxytyrosol-Rich Aqueous Olive Pulp Extract (HIDROX ® ) and Its Use as a Virucidal Cream for Topical ApplicationArticle Published on 2021-02-022022-10-28 Journal: Viruses [Category] COVID-19, [키워드] activities activity acute respiratory syndrome addition Antiviral application applied approach aqueous aqueous olive pulp extract auxiliary changed changes in compounds contribute coronavirus Cream evaluated exhibit Extract glycosylated glycosylation hydroxytyrosol in vitro increase in investigated measure Measures mechanism of action medication molecular weight natural-derived material Olive Pulp SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 Spike proteins Spread suggested the spike protein topical topical application Treatment vaccination viral genome virucidal virus inactivation [DOI] 10.3390/v13020232 PMC 바로가기 [Article Type] Article
Is there scientific evidence of the mouthwashes effectiveness in reducing viral load in Covid-19? A systematic reviewReview Published on 2021-02-012022-10-29 Journal: Journal of Clinical and Experimental Dentistry [Category] COVID-19, [키워드] appear article articles base Care carried chlorhexidine clinical Concentration concentrations COVID-19 decrease Dilution effective Effectiveness Evidence human saliva hydrogen hydrogen peroxide in viral in vitro independent Intervention Material and Method MERS-CoV Mouthwash mouthwashe mouthwashes performed peroxide reduce reducing reduction Research Result review Saliva SARS-CoV selected Seven Support systematic review tested Viral load virucidal viruses [DOI] 10.4317/jced.57406 PMC 바로가기 [Article Type] Review
The European tiered approach for virucidal efficacy testing – rationale for rapidly selecting disinfectants against emerging and re-emerging viral diseasesPerspective Published on 2021-01-212022-10-31 Journal: Eurosurveillance [Category] COVID-19, [키워드] acute respiratory syndrome addition Antiviral approach auxiliary Committee complex coronavirus COVID-19 develop Disinfectants effective Efficacy emerging virus European European Standardisation evaluate group hand hygiene hygiene include Infection prevention and control Isolation marker Masks outbreak pandemic physical distancing preventive measure quarantine reduce risk of transmission SARS-CoV-2 Spread surface disinfection vaccination Vaccines vaccinia virus viral disease virucidal virus viruses working [DOI] 10.2807/1560-7917.ES.2021.26.3.2000708 PMC 바로가기 [Article Type] Perspective
Virucidal effect of povidone iodine on COVID-19 in the nasopharynx: A structured summary of a study protocol for an open-label randomized clinical trial비인두에서 COVID-19에 대한 포비돈 요오드의 바이러스 살균 효과: 공개 라벨 무작위 임상 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-01-042022-09-10 Journal: Trials [Category] 임상, [키워드] 6 hour 6 hours acute renal failure adverse effect adverse effects adverse event adverse events anticipated Arm-1 ARMS assigned baseline being randomized Blinding both groups chronic renal failure clinical trial college comparator Concentration conducted confirmed case COVID-19 COVID-19 case COVID-19 virus creatinine criteria Data analysis diagnosed diet disease dissemination distilled water DMC Efficacy element eligibility assessment estimated glomerular filtration rate evaluate exclusion filtration rate Final glomerular filtration rate groups Identifier in both groups include Inclusion inclusion criteria independent Informed consent Intervention intervention arm intervention arms intervention group invasive involved Iodine KDIGO lactating masking Microsoft Excel Modification nasal Nasal Irrigation Nasal spray nasopharynx Noninvasive ventilation number objective Occurrence Open-label Other outcome parallel-group participant Patient performed Placebo positive Povidone Iodine pregnant women Primary outcome proportion protocol random number generation randomization Randomized randomized clinical trial RCT receive recruited Registered renal renal disease renal failure required routine care Sample size screened sealed secondary outcome sensitivity Seven single-center Stage statistician status Study protocol supplementary material Symptom Thyroid thyroid disease Trial trial protocol Trial registration Version virucidal virus website [DOI] 10.1186/s13063-020-04963-2 PMC 바로가기 [Article Type] Letter
Inactivation of Human Coronavirus by Titania Nanoparticle Coatings and UVC Radiation: Throwing Light on SARS-CoV-2Article Published on 2020-12-242022-10-28 Journal: Viruses [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome approved assays Atypical coating coronavirus coronavirus disease coverslips COVID-19 COVID-19 case COVID-19 symptom described disease effective Efficacy examined Genetic HCoV-NL63 help highest hospitals human coronavirus individual LIGHT majority nanoparticle outbreak pathogenic Precaution Protective Quantitative Radiation RT-qPCR SAR-CoV-2 SARS-CoV-2 Schools Spread The United States throwing Titania TNP coating UV Vaccines virucidal virus virus inactivation virus infectivity virus spread [DOI] 10.3390/v13010019 PMC 바로가기 [Article Type] Article
Post-exposure prophylaxis with hydroxychloroquine for the prevention of COVID-19, a myth or a reality? The PEP-CQ StudyResearch article Published on 2020-12-012022-10-05 Journal: International journal of antimicrobial agents [Category] SARS, 임상, [키워드] 95% CI adverse event assigned asymptomatic individual Contact Controlled clinical trial COVID-19 COVID-19 case COVID-19 patient Day Direct drug Follow-up group HCQ highest home quarantine household contact Hydroxychloroquine hygiene in vitro incidence of COVID-19 Inconclusive individuals International laboratory-confirmed NNT Occurrence offered Open-label over pandemic participant Participants Post-exposure prophylaxis Prevent prevention prevention of COVID-19 Prophylaxis randomised clinical trial required risk risk reduction SARS-CoV-2 SARS-COV-2 infection Serious Adverse Events significantly social distancing therapy Travel virucidal [DOI] 10.1016/j.ijantimicag.2020.106224 [Article Type] Research article
SARS-CoV-2 Inhibition by Sulfonated CompoundsCommunication Published on 2020-11-302022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] ACE2 Antiviral attachment inhibitor binding Cell cellular entry Compound coronavirus demonstrated enzyme group heparan sulfates inhibition inhibitory activity Interaction investigated mechanism non-toxic Prevent receptor reduced SARS-CoV-2 SARS-CoV2 shown Spike protein sulfated sulfonated these compound Treatment vesicular stomatitis virus virucidal virus viruses [DOI] 10.3390/microorganisms8121894 PMC 바로가기 [Article Type] Communication
EGYVIR: An immunomodulatory herbal extract with potent antiviral activity against SARS-CoV-2Research Article Published on 2020-11-182022-10-28 Journal: PLoS ONE [Category] COVID-19, SARS, [키워드] acute respiratory syndrome antiviral activity antiviral agent Antiviral effect cell lines Combination coronavirus Cytokine storm Cytokines storm elements Huh-7 IL-6 immunomodulatory in vitro in vitro study in-silico In-vitro infection process NF-kβ nuclear translocation P50 pandemic pathway SARS-CoV-2 severe cases the disease the SARS-CoV-2 TNFα Vaccine virucidal [DOI] 10.1371/journal.pone.0241739 PMC 바로가기 [Article Type] Research Article
Infectivity of SARS-CoV-2 and Other Coronaviruses on Dry Surfaces: Potential for Indirect TransmissionReview Published on 2020-11-182022-10-30 Journal: Materials [Category] COVID-19, [키워드] acute respiratory syndrome ambient analyzed Antiviral conditions contaminated surface contaminated surfaces coronavirus COVID-19 decrease Disinfection Dry effective Efficiency Factor fomites globe hygiene Infectivity investigated knowledge limitation measure media mitigate occur Other outlined pandemic persistence Personal protective equipment Potential preventive measure Research researcher SARS-CoV-2 SARS-CoV-2 transmission social distancing spread of COVID-19 stability Sunlight survival temperature the SARS-CoV-2 Transmission virucidal virus [DOI] 10.3390/ma13225211 PMC 바로가기 [Article Type] Review
Ibuprofen, a traditional drug that may impact the course of COVID-19 new effective formulation in nebulizable solution분무 가능한 용액에서 COVID-19의 새로운 효과적인 제형의 과정에 영향을 미칠 수 있는 전통 약물, 이부프로펜Article Published on 2020-11-012022-09-11 Journal: Medical Hypotheses [Category] SARS, 치료제, [키워드] 2019-nCoV 2019-nCoV infection absence Actin actin protein actin proteins Administered airway airways anti-inflammatory property Bacteria Bioavailability biological property Burkholderia caused Concentration contribute coronavirus Course COVID-19 demonstrated dose duplication Effect effective enveloped virus enzyme family filament health emergency hydrosoluble hypertonic Hypothesis ibuprofen include Infection inhibit Interaction investigator involved ionic strength kill local inflammation lung Lung inflammation Lungs membrane methicillin methicillin-resistant Staphylococcus aureus mucolytic nebulized NIH Other oxygen Pathogenesis people with COVID-19 physico-chemical properties physico-chemical property prevention strategies reactive oxygen species reactive oxygen specy reduce reduced reorganization required ROS SARS-CoV-2 Spread Staphylococcus aureus systemic inflammatory response systemic inflammatory responses therapeutic therapeutic effect virucidal virus virus infection water [DOI] 10.1016/j.mehy.2020.110079 PMC 바로가기 [Article Type] Article