GSK-3 Inhibition as a Therapeutic Approach Against SARs CoV2: Dual Benefit of Inhibiting Viral Replication While Potentiating the Immune ResponseImmunology Published on 2020-06-262022-11-01 Journal: Frontiers in Immunology [Category] Coronavirus, MERS, SARS, [키워드] adaptive Against Analysis Anti-viral CD8+ CD8+: T lymphocyte subsets connection conserved COVID COVID-19 CTL cytolytic drug ENhance function GSK-3 Hypothesis immune response information inhibit inhibition inhibitor knowledge limit mice N protein natural killer NK cell pandemic Phosphorylation protein sequences question reducing reduction in Replication residue response responses SAR SARS-CoV2 SARS-CoV2 infection Serine small molecule inhibitor T-cell T-Cells (or lymphocytes) the N protein Therapeutic approach therapeutic approaches therapy Vaccine viral (or virus) viral infection viral replication virus while [DOI] 10.3389/fimmu.2020.01638 PMC 바로가기 [Article Type] Immunology
From Preparedness to Recovery: Learning Lessons Of COVID-19 Outbreak from ChinaViewpoint Published on 2020-06-262022-10-31 Journal: The East African Health Research Journal [Category] COVID-19, [키워드] acute respiratory syndrome Admission affected catastrophic China Chinese city Comorbidities containment measures coronavirus coronavirus disease COVID-19 COVID-19 outbreak Critical disease Diseases form highest hospitals implementation intensive care Italy learning lesson mortality rate Novel coronavirus pandemic Patient Population public health public health authority reported SARS-CoV-2 virus World Health Organization Wuhan [DOI] 10.24248/eahrj.v4i1.616 PMC 바로가기 [Article Type] Viewpoint
Estimation and prediction of COVID-19 cases in Brazilian metropolises *Original Article Published on 2020-06-262022-10-29 Journal: Revista Latino-Americana de Enfermagem [Category] COVID-19, MERS, SARS, [키워드] Aislamiento Social applied confirmed case coronavirus Coronavirus infections country COVID-19 COVID-19 case death Enfermagem Enfermería epidemiología Epidemiología Epidemiologic Models epidemiological Epidemiology estimate estimation expressive Forecasting high mortality highest Infecções por Coronavirus infecciones por coronavirus Infection Isolamento Social mathematical Ministry of Health Modelos Epidemiológicos New coronavirus nine number of infected Nursing objective observé Predicción preventive measure Previsões Result Rio de Janeiro social isolation Spread susceptible transmission rate upward curve virus [DOI] 10.1590/1518-8345.4501.3345 PMC 바로가기 [Article Type] Original Article
COVID-19 and the production of knowledge regarding recommendations during pregnancy: a scoping review *Review Article Published on 2020-06-262022-10-29 Journal: Revista Latino-Americana de Enfermagem [Category] COVID-19, MERS, SARS, [키워드] analyzed Atención Prenatal Care clinical manifestations collected complications composed Coronavirus infections COVID-19 Cuidado Pré-Natal database Diagnosis disease Embarazo emotional Enfermagem Obstétrica Enfermería Obstétrica Evidence Final Future Gravidez Guidance independent Infecções por coronavírus infecciones por coronavirus Infection Infectious Disease Transmission, Vertical Isolation knowledge lack medications Novel coronavirus objective Obstetrícia Obstetric Nursing Obstetricia obstetrics oxygen support placental Pregnancy pregnant women prenatal care Psychological recommendation Research resource Result severe cases Support Transmisión Vertical de Enfermedad Infecciosa Transmissão Vertical de Doença Infecciosa Transmissibility Transmission Treatment Vaccine development virus vital signs [DOI] 10.1590/1518-8345.4523.3348 PMC 바로가기 [Article Type] Review Article
Severe COVID-19: NLRP3 Inflammasome DysregulatedImmunology Published on 2020-06-262022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] activate Activation Adaptive immune response COVID-19 COVID-19 patient Cytokine storm downregulate dysregulated endogenous adjuvant activity FIVE HMGB1 immune immune system NLRP3 NLRP3 inflammasome potential treatment option reduced resulting SARS-CoV-2 severe COVID-19 severe COVID-19 patients therapy tissue damage virus [DOI] 10.3389/fimmu.2020.01580 PMC 바로가기 [Article Type] Immunology
N-glycosylation of infectious bronchitis virus M41 spike determines receptor specificityResearch Article Published on 2020-06-262022-10-30 Journal: The Journal of General Virology [Category] Coronavirus, [키워드] attachment protein binding comparable coronavirus Critical determine expressed generate genetics growth host cells IBV Infectious Bronchitis Virus initiated investigated knock-out M41 mutant mutants Mutation N-glycosylation N-glycosylation site RBD RBDs receptor Receptor binding domain shown sialic acid specificity Spike protein the RBD tissue virus virus replication virus–host interactions wild-type [DOI] 10.1099/jgv.0.001408 PMC 바로가기 [Article Type] Research Article
Data and Text Mining Help Identify Key Proteins Involved in the Molecular Mechanisms Shared by SARS-CoV-2 and HIV-1Communication Published on 2020-06-262022-10-30 Journal: Molecules [Category] COVID-19, SARS, [키워드] acute respiratory syndrome antiretroviral drug antiviral drugs applied caused Cell coronavirus CoV Data mining disorder effective Epidemics example HIV-1 Human immunodeficiency virus identify immune response Infection Inflammation involved molecular molecular mechanism mutant New Pandemics pathway Regulation Remdesivir Ritonavir SARS SARS-CoV-2 Spread suggested targets text text mining Therapeutic approach variant virus virus–host interactions [DOI] 10.3390/molecules25122944 PMC 바로가기 [Article Type] Communication
Development and Evaluation of a Duo SARS-CoV-2 RT-qPCR Assay Combining Two Assays Approved by the World Health Organization Targeting the Envelope and the RNA-Dependant RNA Polymerase (RdRp) Coding RegionsArticle Published on 2020-06-252022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] Accuracy acute respiratory syndrome Berlin caused circulation coronavirus COVID-19 demonstrated development Diagnosis diagnostic diagnostics emerging envelope false-negative Germany impair intensity Internal control molecular Molecular diagnosis mutations outbreak parental Paris performed polymorphism preparedness Prevent RdRP Real-time PCR Region respiratory response resulting RNA robust RT-qPCR RT-qPCR assay SARS-CoV-2 screening tests selected sensitivity specificity TaqMan targeting unique university virus WHO World Health Organization [DOI] 10.3390/v12060686 PMC 바로가기 [Article Type] Article
Universal masking is an effective strategy to flatten the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) healthcare worker epidemiologic curveResearch Brief Published on 2020-06-252022-10-30 Journal: Infection Control and Hospital Epidemiology [Category] COVID-19, MERS, SARS, [키워드] effective healthcare worker Respiratory Coronavirus SARS-CoV-2 Universal virus [DOI] 10.1017/ice.2020.313 PMC 바로가기 [Article Type] Research Brief
MicroGMT: A Mutation Tracker for SARS-CoV-2 and Other Microbial Genome SequencesMicrobiology Published on 2020-06-252022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] applied bioinformatics COVID-19 database Epidemiology Evolution genome sequence genomes identify INDEL microbial molecular molecular evolution Mutation mutations Other researcher SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 virus sequence sequenced Spread virus [DOI] 10.3389/fmicb.2020.01502 PMC 바로가기 [Article Type] Microbiology