RpoS Plays a Central Role in the SOS Induction by Sub-Lethal Aminoglycoside Concentrations in Vibrio choleraeRpoS는 Vibrio cholerae에서 치명적이지 않은 아미노글리코사이드 농도에 의한 SOS 유도에서 중심 역할을 합니다Research Article Published on 2013-04-112022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] addressed Aminoglycoside Antibiotic resistance Antibiotics Author Bacteria Bacterial caused cellular mechanism cellular mechanisms CENTRAL Concentration connection conserved corollary different DNA DNA damage DNA damaging E. coli Escherichia coli flow cytometry found Frequency fusion gene transfer Genetic Genome genomic plasticity gram growth guanine horizontal gene Horizontal gene transfer increase in induce induction inhibit inhibitory concentration Klebsiella pneumoniae leads low dose Mutation mutations Other over-expression oxidative oxidative stress oxidative stress response oxidized oxygen paradigm pathogen Pathogens pathway Pathways physiological effect physiological effects physiological response pneumoniae Prevent promoter Protein reactive oxygen specy regulated related role RpoS shown SOS SOS response Stress stress conditions stress response Testing tobramycin transfer V. cholerae Vibrio cholerae [DOI] 10.1371/journal.pgen.1003421 PMC 바로가기 [Article Type] Research Article
Tetraspanin Is Required for Generation of Reactive Oxygen Species by the Dual Oxidase System in Caenorhabditis elegansTetraspanin은 Caenorhabditis elegans의 이중 산화 효소 시스템에 의한 반응성 산소 종의 생성에 필요합니다Research Article Published on 2012-09-202022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Activation addition aerobic aerobic metabolism aging Analysis association Author biosynthetic biosynthetic pathway Caenorhabditis Caenorhabditis elegan Caenorhabditis elegans cause Cell cell surface cellular cellular component cellular components co-expression collagen Combination complex complexes conjunction conserved Defense deficiency demonstrated dependent on disease DOXA dual elegan enzyme Enzymes Evidence experiment exposure to Extracellular matrix failure functions Generation Genetic genetic mutation genetics Host host defense hydrogen hydrogen peroxide Imbalance Immunity in vitro in vivo inhibit isozyme less lipids mammalian cells mammals maturation mechanism member metabolism modifications mucosal mutant mutants Mutation NADPH NADPH oxidase nucleic acids Oxidase oxidative stress oxygen pathway peroxidase physiological produced Protein provide Radiation reactive reactive oxygen species redox state regulated Regulatory required responsible restored ROS Signaling signaling pathway Specy suggested System tetraspanin the cell Thyroid thyroid hormone toxic tyrosine unique UV light [DOI] 10.1371/journal.pgen.1002957 PMC 바로가기 [Article Type] Research Article
Viral Loads in Clinical Specimens and SARS ManifestationsResearch Published on 2004-09-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] acute respiratory syndrome anatomical clinical collected death Desaturation detectable diarrhea different hepatic dysfunction laboratory abnormality laboratory-confirmed load manifestation mechanical ventilation nasopharyngeal aspirate onset of symptom oxygen Pathogenesis Patient Replication Research retrospective risk RT-qPCR SARS specimen Urinalysis Urine Viral load was performed [DOI] 10.3201/eid1009.040058 PMC 바로가기 [Article Type] Research