Molecular detection and genetic characterization of Mycoplasma gallisepticum , Mycoplama synoviae, and infectious bronchitis virus in poultry in MyanmarResearch Article Published on 2019-07-252022-10-28 Journal: BMC veterinary research [Category] Coronavirus, MERS, [키워드] Analysis Asian Avian Influenza Avian mycoplasmosis collected disease distribution eight Genetic Genotype IBV identifying Infectious Bronchitis Virus information isolate maintain Myanmar Mycoplasma Mycoplasma gallisepticum Mycoplasma synoviae pathogen Periodic polymerase chain protocols reported required Respiratory disease Respiratory pathogens Result Sample serotype Strains Surveillance vaccination Vaccine variant [DOI] 10.1186/s12917-019-2018-2 PMC 바로가기 [Article Type] Research Article
Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancyOct1/Pou2f1은 결장 재생에 선택적으로 필요하며 결장 악성 종양을 조절합니다.Research Article Published on 2019-05-062022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] allele blocked Cancer Cell Characteristics ChIPseq Colon Colon cancer colon carcinoma Colorectal Colorectal cancer damage death deleted Deletion determine dextran diagnosed differentially expressed differentially expressed gene Differentially expressed genes disease driven by Effect etiology expressed Factor gastrointestinal tract Gene Expression gene target Gut gut stem cell homeostasis identify in vitro in vivo incidence intestinal stem cell Intestinal stem cells maintain maintenance malignancy mechanism metabolism mitotic Mortality Organoid organoids outcome outcomes overlap passage pathophysiology Patient Physiology Pou2f1 preserved proceed promote protein level regulate required significantly sodium sodium sulfate stability stem cell stem cells Stress stress response sulfate Suppressor gene target gene Target genes targets The United States transcription factor Treatment Tumor tumor suppressor tumor suppressor gene United States [DOI] 10.1371/journal.pgen.1007687 PMC 바로가기 [Article Type] Research Article
Cyclic di-AMP regulation of osmotic homeostasis is essential in Group B Streptococcus삼투성 항상성의 순환 di-AMP 조절은 B군 연쇄상 구균에서 필수적입니다Research Article Published on 2018-04-162022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence accumulating accumulation assumed Bacteria Bacterial betaine bind binding cellular cellular physiology compensatory mutations conditions conserved Control cyclic dacA Deletion demonstrated dependent on enzyme etiological agent expression function functional glycine glycine betaine group growth homeostasis host cell host cells host-pathogen interactions hyperosmotic identification identify Infection involved leads Loss loss-of-function loss-of-function mutation maintain mechanism medium Meningitis monophosphate mutant Mutation Neonatal nucleotide nucleotides opportunistic pathogen osmolyte osmoregulation osmotic osmotic regulation pathogen pathway phenotype Potassium predominant promoter Protein regulate Regulation second messenger second messengers secondary messenger septicaemia Streptococcus Streptococcus agalactiae susceptibility Transcription transcriptional viability [DOI] 10.1371/journal.pgen.1007342 PMC 바로가기 [Article Type] Research Article
Peptide-Based Membrane Fusion Inhibitors Targeting HCoV-229E Spike Protein HR1 and HR2 DomainsArticle Published on 2018-02-062022-10-29 Journal: International Journal of Molecular Sciences [Category] Coronavirus, [키워드] Administered Antiviral cell-cell fusion coronavirus 229E domains effective fusion HCoV-229E heptad repeat Human Immunocompromised patient Infants Infection inhibit inhibited inhibitor intranasally Lower respiratory tract maintain membrane fusion peptide peptide-based pseudotyped reported Safe severe disease spike Spike protein targeting treat Treatment [DOI] 10.3390/ijms19020487 PMC 바로가기 [Article Type] Article
Wor1 establishes opaque cell fate through inhibition of the general co-repressor Tup1 in Candida albicansWor1은 Candida albicans에서 일반적인 공동 억제 인자 Tup1의 억제를 통해 불투명한 세포 운명을 설정합니다.Research Article Published on 2018-01-162022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence Affect Affinity purification analyses Analysis approach Author bypass Candida Candida albican Candida albicans carbon carbon source carbon sources Cell cell fate cells colonization colonize commensal complex protein explain expressed facilitate Factor function functions fungal Genetic gut microbiota Host identify individuals induce Loss maintain mass spectrometry mass spectroscopy master regulator mechanism molecular Morphological occur pathogen pathogenic phenotypic plasticity positive feedback promoter Proteins provide Region regulated Regulation regulatory circuit repression repressor serious infection serious infections stability starting switching temperature transcriptional transcriptional repressor undergo white Wor1 [DOI] 10.1371/journal.pgen.1007176 PMC 바로가기 [Article Type] Research Article
How Do the First Days Count? A Case Study of Qatar Experience in Emergency Risk Communication during the MERS-CoV OutbreakCase Report Published on 2017-12-192022-10-30 Journal: International Journal of Environmental Research an [Category] Coronavirus, [키워드] activity CERC characterized collected communication contributed coordination Course creating crisis Day develop Emergency emergency risk communication Epidemic ERC event experience Frame help information maintain management media MERS MERS-CoV Middle East outbreak performed provide public health authorities Qatar released Research risk the epidemic [DOI] 10.3390/ijerph14121597 PMC 바로가기 [Article Type] Case Report
Biofilm microenvironment induces a widespread adaptive amino-acid fermentation pathway conferring strong fitness advantage in Escherichia coli생물막 미세 환경은 대장균에 강력한 적합성을 부여하는 광범위한 적응 아미노산 발효 경로를 유도합니다Research Article Published on 2017-05-192022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] 1-propanol adaptive aerobic Amino acid amino-acid Bacterial bacterial communities balance biofilm cellular change characterized Clostridia competition complex condition conditions contribute Degradation E . coli Enterobacteriaceae Escherichia coli exploration Genetic modifications growth hypoxic hypoxic condition hypoxic conditions identify induce liquid cultures maintain metabolic pathway metabolic pathways metabolism microenvironment pathway physiological responses produced propanol provide reducing threonine Trigger widespread [DOI] 10.1371/journal.pgen.1006800 PMC 바로가기 [Article Type] Research Article
Transcription Factors Encoded on Core and Accessory Chromosomes of Fusarium oxysporum Induce Expression of Effector GenesFusarium oxysporum의 코어 및 액세서리 염색체에 인코딩된 전사 인자는 이펙터 유전자의 발현을 유도합니다Research Article Published on 2016-11-172022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Accessory accessory chromosome accessory chromosomes activate autonomous bind binding site chromatin chromatin condensation chromosome chromosomes colonisation connection conserved constitutive promoter core core genome determine DNA binding effector effectors ENCODE Evolution example expression extreme facilitate Factor FTF1 FTF2 fungal fungi Fusarium GC content Gene Expression Genes Genome genomic genomic region homolog homolog FTF2 homologous Host independent induce Infection Interaction investigated maintain motif motifs nine occurred oligonucleotide oligonucleotide arrays outcome overlapping pathogen Pathogenesis pathogenic pathogenicity Pathogens predicted promoters reference strain Region required RNAseq analysis secreted Sge1 specificity strain Strains tomato Transcription transcription factor transcription factor gene transcription factor genes transcription factors transcriptional transcriptionally transfer transferred transposon up-regulated virulence yeast [DOI] 10.1371/journal.pgen.1006401 PMC 바로가기 [Article Type] Research Article
Preventive behaviors by the level of perceived infection sensitivity during the Korea outbreak of Middle East Respiratory Syndrome in 2015MERS Published on 2016-11-162022-10-31 Journal: Epidemiology and Health [Category] Coronavirus, MERS, [키워드] 95% CI 95% confidence interval age Analysis analyzed Characteristics Cluster cluster analysis Community correlated Epidemics Final Gender group Health Infection Local Logistic regression analysis maintain MERS Middle East Middle East respiratory syndrome Coronavirus Neutral nine outbreak participant promote reducing reliability respiratory Risk reduction behavior sensitivity socio-demographic Stress stress level was performed [DOI] 10.4178/epih.e2016051 PMC 바로가기 [Article Type] MERS
Distinct Prion Domain Sequences Ensure Efficient Amyloid Propagation by Promoting Chaperone Binding or Processing In Vivo고유한 프리온 도메인 서열은 생체 내 샤페론 결합 또는 처리를 촉진하여 효율적인 아밀로이드 증식을 보장합니다Research Article Published on 2016-11-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] acting aggregate Alter Amino acid amyloid assembly binding change chaperone chaperones complementary composed conformation conformational conformational flexibility contribute creating efficient element elements Ensure functional in vitro in vivo inheritance Interaction maintain mechanism molecular observation occur open persistence physical physical properties predict prion processing promote Promoting Propagation Protein Protein misfolding Proteins proximal PSI question Regulation required resulting sequence Spectrum stability Transmission yeast [DOI] 10.1371/journal.pgen.1006417 PMC 바로가기 [Article Type] Research Article