T cells – Page 102 – Communicable Diseases Research

A Genome-Wide Integrative Genomic Study Localizes Genetic Factors Influencing Antibodies against Epstein-Barr Virus Nuclear Antigen 1 (EBNA-1)

게놈 전체에 걸친 통합 게놈 연구는 엡스타인-바 바이러스 핵 항원 1(EBNA-1)에 대한 항체에 영향을 미치는 유전적 요인을 국소화합니다.

Research Article

Published on 2013-01-102022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils

Research

Published on 2012-05-292022-10-30
Journal: Journal of Neuroinflammation [Category] Coronavirus,

[키워드] affecting Autoimmune blockade CD4 CD4⁺ T cells Central nervous system clinical consequence CNS compared complex coronavirus cytokine Demyelination detrimental disease downstream effector molecule Encephalomyelitis expression Factor feedback loops GM-CSF IFN-γ IFN-γ IL-17 independent Infected inflammatory condition inflammatory disease Interaction mechanism memory mice morbidity Mortality murine Neurotropic coronavirus neutrophil neutrophil infiltration Neutrophils not express pathogenic positive PROTECT provided recipient reduced reducing relative contribution rescued response Result survival T cell T cells Th1 Th17 Th17 cell tissue damage Transcription transcriptional regulation transfer upregulation virus was used wild-type
[DOI] 10.1186/1742-2094-9-104 PMC 바로가기 [Article Type] Research

Future of an “Asymptomatic” T-cell Epitope-Based Therapeutic Herpes Simplex Vaccine

Article

Published on 2012-04-232024-09-04
Journal: Future Virology [Category] 대상포진,

[키워드] and Asymptomatic Antigen epitope herpes HSV-1 HSV-2 Human symptomatic T cells therapeutic Vaccine
[DOI] 10.2217/fvl.12.22 PMC 바로가기 [Article Type] Article

Integration of Immunity with Physical and Cognitive Function in Definitions of Successful Aging

Review

Published on 2012-02-272024-09-04
Journal: Aging and Disease [Category] 대상포진,

[키워드] immune remodeling NK cells Older adults Successful aging T cells
PMC 바로가기 [Article Type] Review

Programmed Death (PD)-1-Deficient Mice Are Extremely Sensitive to Murine Hepatitis Virus Strain-3 (MHV-3) Infection

Research Article

Published on 2011-07-072022-10-29
Journal: PLoS Pathogens [Category] Coronavirus,

[키워드] activate anti-IFN-γ anti-TNF-α Author blockade cascades CD4 CD8 cells characteristic co-expressed Coagulation Combination Control damaged demonstrated described determined exhibited expression Fgl2 FH fibrinogen Fluorescence fulminant viral hepatitis functional hepatocellular IFN-γ immunopathological immunopathological damage Immunotherapy in vivo Infection inhibitory receptor initiate injection investigated led to limit liver Liver damage Lymph node lymph nodes mAb Macrophage maintain mechanism mice Mortality mortality rate mRNA multiple organs murine hepatitis virus Necrosis NK cell occurred organ Pathogenesis peripheral tolerance produced promote Protein Quantitative reduced related RT-PCR sensitive Signaling significantly higher spleen T cells tissue tissue damage tissue lesion tissue lesions TNF-α Transcription was determined wild type wild-type
[DOI] 10.1371/journal.ppat.1001347 PMC 바로가기 [Article Type] Research Article

Novel application of Ki67 to quantify antigen-specific in vitro lymphoproliferation

Ki67의 새로운 적용을 통해 항원 특이적 시험관 내 림프 증식을 정량화하다

Research Paper

Published on 2010-10-312024-08-16
Journal: Journal of Immunological Methods [Category] 파상풍,

[키워드] cellular proliferation clinical immunology Ki67 OG, Oregon Green PPD, purified protein derivative T cells TT, tetanus toxoid Vaccine
[DOI] 10.1016/j.jim.2010.08.007 PMC 바로가기 [Article Type] Research Paper

A Protective Role for ELR+ Chemokines during Acute Viral Encephalomyelitis

Research Article

Published on 2009-11-062022-10-29
Journal: PLoS Pathogens [Category] Coronavirus,

[키워드] abrogated absence acute viral infection Alter antibody Author blocking Blood Brain Central nervous system characterized chemokine Chemokine receptor chemotaxis clinical outcomes CNS compensatory mechanism consequence contribute CXCL1 CXCL2 CXCL5 CXCR2 Defense defined directional Encephalitis Encephalomyelitis Evidence expressed expressing expression facilitate functional highlight Host impair in vitro increased expression indicated Infection infiltration Inflammatory Injury inoculation involved leukocytes Ligand lymphocyte mice microbial infection Migration modulate Mortality mouse hepatitis virus myeloid cells neurotropic neutralization neutrophil Neutrophils pathogen poliomyelitis proinflammatory receptor recruitment reduced reduction required role shown Signaling survived T cell responses T cells transcript viral clearance viral infection viral replication viral-induced virus was determined
[DOI] 10.1371/journal.ppat.1000648 PMC 바로가기 [Article Type] Research Article

Evasion by Stealth: Inefficient Immune Activation Underlies Poor T Cell Response and Severe Disease in SARS-CoV-Infected Mice

Research Article

Published on 2009-10-232022-10-29
Journal: PLoS Pathogens [Category] Coronavirus, MERS,

[키워드] activate activated Activation Adaptive immune response allergic alveolar macrophage animal model Anti-viral Antigen Author BALB/c mice caused characterized correlated CoV dendritic cell dendritic cells deplete develop DLN draining lymph node Epidemic feature Human human disease human population humans immune response individual inefficient Infected Infection inhibitory inhibitory effect initial Liposome lung lymphopenia MA15 Macrophage mice morbidity and mortality mouse-adapted SARS-CoV Novel coronavirus occurred Patient Poor Prevent prolonged virus persistence PROTECT respiratory Respiratory disease response severe severe disease severe respiratory disease T cell response T cells Therapies TLR3 Toll-like receptor transfer treated virus virus clearance virus excretion virus-specific T cell
[DOI] 10.1371/journal.ppat.1000636 PMC 바로가기 [Article Type] Research Article

In vitro evidence that commercial influenza vaccines are not similar in their ability to activate human T cell responses 1

Article

Published on 2009-03-162023-06-23
Journal: Vaccine [Category] 신종인플루엔자,

[키워드] Influenza T cells Vaccine
[DOI] 10.1016/j.vaccine.2008.09.092 PMC 바로가기 [Article Type] Article

Neonatal pneumococcal conjugate vaccine immunization primes T cells for preferential Th2 cytokine expression: A randomized controlled trial in Papua New Guinea

신생아 폐렴구균 결합 백신 면역화가 T 세포를 Th2 사이토카인 발현을 선호하도록 준비시킴: 파푸아뉴기니에서의 무작위 대조 시험

Article

Published on 2009-02-252024-08-05
Journal: Vaccine [Category] 폐렴구균 감염증,

[키워드] Neonatal pneumococcal conjugate vaccine T cells
[DOI] 10.1016/j.vaccine.2008.12.046 PMC 바로가기 [Article Type] Article