COVID-19: Changing Trends and Its Impact on Future of DentistryReview Article Published on 2020-05-292022-10-29 Journal: International Journal of Dentistry [Category] COVID-19, [키워드] Care Changing Characteristics Chinese horseshoe bat clinical feature Contact coronavirus disease COVID-19 COVID-19 disease creating cross Dental health dentistry Future Health Impact Infection infection control management protocol MERS-CoV Nosocomial infection occur outbreak Patient Prevent provide risk SARS-CoV Spread Transmission trend virus worldwide pandemic [DOI] 10.1155/2020/8817424 PMC 바로가기 [Article Type] Review Article
Analysis of Outbreak and Global Impacts of the COVID-19Article Published on 2020-05-292022-10-31 Journal: International journal for equity in health [Category] COVID-19, [키워드] Affect affected affecting Antarctica bats caused China Corona virus country COVID-19 COVID-19 outbreak death deaths global impacts global pandemic globe Human Impact infect killing measure observation outbreak pandemic raised regions Severe acute respiratory syndrome (SARS) Spread the disease the vaccine Travel Treatment Vaccine virus while Wuhan, China [DOI] 10.3390/healthcare8020148 PMC 바로가기 [Article Type] Article
Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate modelReport Published on 2020-05-292022-10-28 Journal: Science (New York, N.y.) [Category] COVID-19, MERS, SARS, [키워드] absence acute respiratory syndrome animal model bronchiolar cause ciliated epithelial cell Clinical sign Comparative coronavirus coronavirus disease Coronaviruses COVID-19 cynomolgus macaque Diffuse alveolar damage disease drug treatment Effectiveness extreme foci Human human coronavirus humans Infection Influenza inoculated intestinal tract Isolation Like lung lesion Lung pathology macaque macaques MERS MERS-CoV infection Middle East nasal nasal mucosa nose and throat Older pandemic coronavirus Pathogenesis pathogenesis of COVID-19 pathology Patient peaked pneumocyte provide SARS-CoV SARS-CoV infection SARS-CoV infections SARS-CoV-2 SARS-COV-2 infection Science severe symptom Symptoms syndrome Therapeutic strategies type I type II pneumocytes upper respiratory tracts Vaccine virus [DOI] 10.1126/science.abb7314 PMC 바로가기 [Article Type] Report
An Online Observational Study of Patients With Olfactory and Gustory Alterations Secondary to SARS-CoV-2 InfectionObservational Study Published on 2020-05-292022-10-04 Journal: Frontiers in Public Health [Category] MERS, SARS, 임상, [키워드] Ageusia alteration Anosmia Clinical characteristics contribute coronavirus coronavirus epidemics COVID-19 cross-sectional Epidemic epithelial explained Frequency greater Gustatory Hypogeusia Hyposmia Infection Influenza virus material nasal nasal congestion neurological olfactory Olfactory alteration olfactory alterations olfactory/gustatory online questionnaire parainfluenza virus Patient patients with SARS-CoV-2 performed presenting produced questionnaire reported response rhinovirus SARS-CoV-2 SARS-COV-2 infection secondary to virus while [DOI] 10.3389/fpubh.2020.00243 PMC 바로가기 [Article Type] Observational Study
Particulate multivalent presentation of the receptor binding domain induces protective immune responses against MERS-CoVResearch Article Published on 2020-05-292022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, [키워드] Antibody Response approach Critical displaying heptad repeat i301 Immunity induce Lower respiratory tract lumazine synthase magnitude MERS-coronavirus MERS-CoV MERS-CoV infection Middle East mucosal neutralization neutralizing capacity Particle Particulate pathogen peptide platform producing Protective protective immune response rabbit RBD Receptor binding domain Region respiratory syndrome coronavirus SARS-CoV-2 spike Spike protein SpyTag-SpyCatcher tested vaccination Vaccine vaccine candidate viral RBD viral replication virus WHO [DOI] 10.1080/22221751.2020.1760735 PMC 바로가기 [Article Type] Research Article
Novel Immunoglobulin Domain Proteins Provide Insights into Evolution and Pathogenesis of SARS-CoV-2-Related VirusesResearch Article Published on 2020-05-292022-10-29 Journal: mBio [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Alpha Analysis arising attenuate beta-coronavirus beta-CoV Combination comparable Complete coronavirus coronavirus disease CoV COVID-19 COVID-19 pandemic determinant domain Evolution evolutionary arms race Factor Genome Genomic analysis genomic region Health Host Host immune response host immunity hosts identify immune immune evasion immune pressure Immunoglobulin individual insight macro modulate MOST novel Novel coronavirus ORF1a ORF8 outbreak Pathogenesis pathogenicity predicted Protein Proteins Receptor binding domain Region SARS SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 protein SARS-like coronavirus scrutiny sequence severity Structural analysis the Spike Transmission unique virus Virus-host interactions viruses widespread [DOI] 10.1128/mBio.00760-20 PMC 바로가기 [Article Type] Research Article
Acute Neurological Care in the COVID-19 Era: The Pandemic Health System RE silience PROGRAM ( REPROGRAM ) Consortium PathwayNeurology Published on 2020-05-292022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] Acute stroke approach Care clinician condition conditions Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 Efficacy Evidence frontline healthcare worker guidelines healthcare worker highlight Intervention management mitigate neurointervention Neuroinvasive neurological pathway Patient patients Personal protective equipment Personal protective equipment (PPE) positive PPE protocol recommendation reperfusion risk of infection Safety stroke surgery System treated Variation virus [DOI] 10.3389/fneur.2020.00579 PMC 바로가기 [Article Type] Neurology
Phenotypic characteristics and prognosis of inpatients with COVID-19 and diabetes: the CORONADO studyArticle Published on 2020-05-292022-11-01 Journal: Diabetologia [Category] COVID-19, MERS, [키워드] 95% CI acute respiratory syndrome Admission age Analysis AST blockers BMI C-reactive protein caused Characteristics Comorbidity Complication conducted Coronavirus-2 covariate COVID-19 COVID-19 patient COVID-19 severity death diabete diabetes Diabetic died discharged Dyspnoea Endpoint feature French Glucose HbA1c hospitalised hypertension independent predictor Infection Inpatient intubation life-threatening Lymphocyte count mechanical ventilation Median BMI men multicentre multivariable analysis multivariable logistic regression Obstructive Participants peer-reviewed performed phenotypic Primary outcome Prognosis Prognostic value RAAS remained reported Result risk of death SARS-CoV-2 Sex significantly supplementary material Therapies tracheal treated Treatment type 2 diabete Univariate analysis virus with COVID-19 [DOI] 10.1007/s00125-020-05180-x PMC 바로가기 [Article Type] Article
Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2Review Article Published on 2020-05-292022-10-04 Journal: Signal Transduction and Targeted Therapy [Category] MERS, SARS, 신약개발, 임상, 치료제, [키워드] “cytokine storm” adaptive adaptive immune system approved biological processe cascade change chemokine Clinical management COVID-19 COVID-19 patients cytokine Cytokine storm Defense develop drugs dysregulation effective drug help highlight Host immune defense immune dysregulation immune response immune signaling pathway immune system immunopathology implicated Infectious diseases Inflammation Inflammatory innate response mechanism Mild molecular pathway pharmacological Prevent reflect SARS-CoV-2 SARS-COV-2 infection Severe case signaling pathway Spread stages standard care Supportive treatments systemic level therapeutic tissue damage treat Treatment triggered urgent investigation Vaccine viral infection virus virus entry widespread [DOI] 10.1038/s41392-020-0191-1 PMC 바로가기 [Article Type] Review Article
Establishment of stable Vero cell lines expressing TMPRSS2 and MSPL: A useful tool for propagating porcine epidemic diarrhea virus in the absence of exogenous trypsinResearch Article Published on 2020-05-292022-10-28 Journal: Virulence [Category] Coronavirus, [키워드] absence activating approach Cell cell line cell lines cell-cell fusion cleaved cleaving complex conditions Culture ENhance epidemic diarrhea Evolution exogenous trypsin expressing facilitate host protease in vitro Isolation isolation and propagation MSPL PEDV Porcine epidemic diarrhea virus promote provide Recombination Replication Research S protein significantly stability tissue sample TMPRSS2 transmembrane serine protease trypsin vaccination Vaccine Variation Vero Cell Vero cell lines viral infection virus [DOI] 10.1080/21505594.2020.1770491 PMC 바로가기 [Article Type] Research Article