A Countrywide Survey in Saudi Arabia Regarding the Knowledge and Attitude of Health Care Professionals about Coronavirus Disease (COVID-19)Article Published on 2020-10-122022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] 2019-nCoV adjusted odds ratio analyzed Attitude Care conducted coronavirus prevention COVID-19 cross-sectional diploma disease domain FIVE geographical region groups hcp Health health care professionals help higher risk independent variable infection control information Kingdom knowledge Ministry of Health multivariate logistic regression nomenclature Odds ratio pandemic percentages positive attitude Preparedness planning professional Qualtrics question questionnaire Region SARS-CoV2 Saudi Arabia SPSS statistical survey variable was performed website [DOI] 10.3390/ijerph17207415 PMC 바로가기 [Article Type] Article
Sperm cryopreservation during the SARS-CoV-2 pandemicSARS-CoV-2 전염병 동안 정자 동결 보존Original Article Published on 2020-10-102022-09-12 Journal: Journal of Endocrinological Investigation [Category] MERS, 진단, [키워드] absence Administered age Altona Diagnostics amplified assist Asymptomatic Bank cancer patient Cancer patients concern Contact contact with COVID-19 cryopreservation Effect exposure to fertilization Genes had no infected patients Italian Italy lockdown management molecular Nasopharyngeal swab pandemic Patient PCR QIAamp viral RNA kit Qiagen questionnaire real time recruited referred to Result risk SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 testing SARS-CoV2 Semen analysis Semen cryopreservation semen sample Semen samples Seminal fluid Sperm sperm bank the SARS-CoV-2 toto Viral RNA with COVID-19 [DOI] 10.1007/s40618-020-01438-8 PMC 바로가기 [Article Type] Original Article
The sequence at Spike S1/S2 site enables cleavage by furin and phospho-regulation in SARS-CoV2 but not in SARS-CoV1 or MERS-CoVArticle Published on 2020-10-092022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] arginine basophilic Biochemistry caused clade cleavage cleave coronavirus enzyme furin in vitro in vivo insertion mechanism MERS-CoV Middle East Molecular biology motif Novel coronavirus outbreak phosphorylated Phosphorylation Protein protein kinases PRRA Regulatory required respiratory S1/S2 S1/S2 site S1/S2 subunits SARS-CoV2 secreted protein sequence Serine spike supported target cells the Spike viral entry [DOI] 10.1038/s41598-020-74101-0 PMC 바로가기 [Article Type] Article
Covid-19 and Diabetes: A Complex Bidirectional RelationshipEndocrinology Published on 2020-10-082022-10-31 Journal: Frontiers in Endocrinology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Affect association Asymptomatic caused Cell contributed coronavirus Coronavirus infection COVID-19 death diabete diabetes Diabetic disease severity exacerbate hyperglycemia hypertension Identified immune system include Infection Infectious disease insulin action ketoacidosis Male sex management MERS microangiopathy obesity Older age outcome pancreatic pandemic pathology pathophysiology potential mechanism relationship risk risk factor SARS-CoV2 SARS-CoV2 infection target tissue Transmission viral toxicity virus [DOI] 10.3389/fendo.2020.582936 PMC 바로가기 [Article Type] Endocrinology
Effect of Triple Combination Therapy With Lopinavir-Ritonavir, Azithromycin, and Hydroxychloroquine on QT Interval and Arrhythmic Risk in Hospitalized COVID-19 PatientsPharmacology Published on 2020-10-082022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] analyzed arrhythmia Arrhythmias Azithromycin baseline cardiovascular comorbidities Characteristics clinical feature Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients diabete Effect electrocardiographic extreme greater Hydroxychloroquine identify incidence increase in interval Lopinavir/ritonavir material Patient pharmacological prevalent provided QT interval QTc QTc interval QTC prolongation Result risk SARS-CoV2 stroke therapy torsades des pointes treated Treatment triple combination triple combination therapy was obtained was recorded ΔQTc [DOI] 10.3389/fphar.2020.582348 PMC 바로가기 [Article Type] Pharmacology
SARS-CoV2 (COVID-19) Pandemic Lockdown Influences Nature-Based Recreational Activity: The Case of BirdersArticle Published on 2020-10-072022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] activities addition affecting behavioral changes birding birdwatching change changed citizen science contribute country Coverage COVID-19 globe influence Interaction leisure less Local lockdown management men observation Older pandemic public health questionnaire Recreation Regulation reported resource respondent response SARS-CoV2 Virological virus infection was related women [DOI] 10.3390/ijerph17197310 PMC 바로가기 [Article Type] Article
Paracetamol-Induced Glutathione Consumption: Is There a Link With Severe COVID-19 Illness?Pharmacology Published on 2020-10-072022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] ACE2 airway angiotensin-converting enzyme 2 anti-inflammatory drug antioxidant Antiviral authority bacterial superinfection cells COVID-19 COVID-19 pandemic COVID-19 patient depleting disease symptoms drug early phase effort Fever glutathione GSH Hospitalized Host Hypothesis increased risk Inflammation management medication Non-steroidal anti-inflammatory drugs NSAID NSAIDS oxidative damage Pain Paracetamol question raise raised receptor Research Risk factors SARS-CoV2 severely ill patients Symptoms the disease treat Treatment viral infection viral infections [DOI] 10.3389/fphar.2020.579944 PMC 바로가기 [Article Type] Pharmacology
Continuous extracorporeal treatments in a dialysis patient with COVID-19Case Report Published on 2020-10-042022-11-01 Journal: CEN case reports [Category] COVID-19, MERS, [키워드] acute respiratory distress acute respiratory syndrome Admission ARDS caused Continuous Continuous renal replacement therapy coronavirus disease Coronavirus-2 COVID-19 Critically ill Critically ill patient cytokine Cytokine storm Cytokines dialysis died direct hemoperfusion effective Efficacy fiber Health IL-6 level Infarction intensive care male pandemic Patient patient with COVID-19 patients with COVID-19 Peritoneal dialysis plasma plasma exchange reported Respiratory failure SARS-COV-2 infection SARS-CoV2 secondary haemophagocytic lymphohistiocytosis serum syndrome the cytokine storm the patient Treatment treatment approach with COVID-19 [DOI] 10.1007/s13730-020-00538-x PMC 바로가기 [Article Type] Case Report
COVID-19 and multiorgan failure: A narrative review on potential mechanismsArticle Published on 2020-10-042023-06-15 Journal: Journal of Molecular Histology [Category] MERS, SARS, [키워드] angiotensin-converting enzyme-2 Coagulation COVID-19 Cytokine storm multi-organ failure SARS-CoV2 [DOI] 10.1007/s10735-020-09915-3 PMC 바로가기
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarateArticle Published on 2020-10-022022-10-04 Journal: Nature Communications [Category] MERS, SARS, 신약개발, 진단, 치료제, [키워드] addition agonist agonists airway anti-inflammatory activity antioxidant Antiviral antiviral activity approved biopsy cell lines cellular clinically consequence coronavirus 2 COVID-19 COVID-19 pathology COVID-19 patients cytopathogenic effect decrease disease effective fumarate Gene Expression Herpe host inflammatory response immunology induce Infection Inflammatory responses inhibit inhibitory effect limit mechanism Microbiology Nrf2 pathogenic pathogenic virus pathogenic viruses pathway pro-inflammatory response Replication required respiratory reveal SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 SARS-CoV2 infection suppressed type I interferon vaccinia virus virus replication Zika virus [DOI] 10.1038/s41467-020-18764-3 PMC 바로가기 [Article Type] Article