Possible SARS-coronavirus 2 inhibitor revealed by simulated molecular docking to viral main protease and host toll-like receptorResearch Article Published on 2020-06-122022-10-31 Journal: Future Virology [Category] COVID-19, [키워드] adopted Analysis Antiviral applied binding energy COVID-19 determine enrichment functional protein GO and KEGG enrichment analysis Host Inflammatory inhibitor Interaction material metabolic process metabolism molecular docking MPro plants protease Protein rutin SARS-coronavirus SARS-CoV-2 main protease selected target therapeutic TLR TLR2 TLR6 TLR7 TLRs Toll-like receptor Toll-like receptors traditional antiviral medicinal plants [DOI] 10.2217/fvl-2020-0099 PMC 바로가기 [Article Type] Research Article
Information Technology–Based Management of Clinically Healthy COVID-19 Patients: Lessons From a Living and Treatment Support Center Operated by Seoul National University HospitalOriginal Paper Published on 2020-06-122022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, SARS, [키워드] adopted app approach assist Care center clinical informatics clinically coronavirus disease COVID-19 COVID-19 patients develop disease severity enhancement epidemiological Government Health Health information technology healthy hospital hospital information system implementation increasingly Infectious disease information Korean lesson management Mobile App objective Patient Patient care patients Questionnaires rate of infection real time responses Result Seoul National University social distancing South Korea Support Symptom Telemedicine Treatment vital sign [DOI] 10.2196/19938 PMC 바로가기 [Article Type] Original Paper
COVID-19 Pandemic in the Italian Population: Validation of a Post-Traumatic Stress Disorder Questionnaire and Prevalence of PTSD SymptomatologyArticle Published on 2020-06-102022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, [키워드] Administered adopted anhedonia appear check collected confirmatory factor analysis correlation COVID-19 COVID-19 emergency COVID-19 pandemic cross-sectional survey demographic diffusion dimensions distress DSM-5 effective Effects evaluate indicated Intervention intrusion Italian Italian population list negative pandemic Post-traumatic stress disorder Prevalence Psychological Psychological distress psychological Impact psychometric properties psychometric property PTSD questionnaire remains uncertain reported risk Significant Sleep disturbance Spread stress symptom Symptomatology Symptoms validation virus [DOI] 10.3390/ijerph17114151 PMC 바로가기 [Article Type] Article
Host transcriptome-guided drug repurposing for COVID-19 treatment: a meta-analysis based approachBioinformatics Published on 2020-06-102022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] acute respiratory syndrome adopted Analysis anti-viral activity approach approved caused cell type CFB connectivity coronavirus Coronavirus disease 2019 COVID-19 CXCL2 CXCL3 drug Drug repurposing DrugBank early infection effective Evidence expression expression profile Factor Factors Gene Expression gene product Host host transcriptome Ifi44 inhibitor Map Meta-analysis pandemic PTGS2 reported required respiratory infection viruses Result SARS-CoV-2 SARS-COV-2 infection subject therapeutic strategy Treatment TYMP upregulated World Health Organization XAF1 [DOI] 10.7717/peerj.9357 PMC 바로가기 [Article Type] Bioinformatics
Chronic Inflammation in the Context of Everyday Life: Dietary Changes as Mitigating FactorsReview Published on 2020-06-102022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] accompanied activated Activation adopted Affect AMPK B cells Biomarker Cancer cardiovascular disease change chronic Chronic low-grade inflammation Combination Community complex Context COVID-19 COX2 demonstrated diabetes diet dietary dietary habit Diseases dose driven by Epidemics Factor fasting fatty acids fiber FoxO Health healthcare help hospitals Human IKK IMPROVE individual individual level Inflammation Inflammatory intervention study IκB MAPK marker Metabolic diseases metabolic disorder MMP9 modulate molecular molecular mechanism Multiple neurodegenerative Nrf2 nuclear pathway Patient polyphenols Polyunsaturated protein kinases public health real-life risk simulation reduced reducing Resilience risk School significantly STAT3 Transcription [DOI] 10.3390/ijerph17114135 PMC 바로가기 [Article Type] Review
Early Detection and Assessment of Covid-19Medicine Published on 2020-06-092022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] adopted assessment assigned Biomarkers Blood Borg change chart Chi-square clinical feature Clinical stage collected common confirmed case correlation cough country detection Diagnosis disease stages elevated exhibited feature Features Frequency global pandemic Hashmi-Asif Covid-19 Chart highest Incubation Laboratory leukopenia lymphopenia membrane Mild Modification morbidity normal Pearson correlation pharyngeal physical quarantine reduce regression analysis representing SARS-CoV-2 scored Spearman Symptom symptoms of COVID-19 thrombopenia transmission rate [DOI] 10.3389/fmed.2020.00311 PMC 바로가기 [Article Type] Medicine
Dietary Diversity among Chinese Residents during the COVID-19 Outbreak and Its Associated FactorsArticle Published on 2020-06-062022-10-31 Journal: Nutrients [Category] COVID-19, [키워드] 95%CI adjusted adopted age alcohol Analysis approach association Characteristics China Chinese Clustering analysis concern conducted confirmed COVID-19 case contributing to COVID-19 COVID-19 cases COVID-19 pandemic cross-sectional dietary dietary behaviors dietary supplements Diversity Emergency Factor feasible health system household household dietary diversity score Impact Isolation Laboratory lockdown no significant difference participant processed Public recruit regions reported resident score significantly higher the median Vitamin C was used with COVID-19 [DOI] 10.3390/nu12061699 PMC 바로가기 [Article Type] Article
How Are We Facing It? Dispatches From Pathology Residents in a COVID-19 Lombardy Hospital우리는 어떻게 직면하고 있습니까? COVID-19 롬바르디아 병원 병리과 레지던트의 파견Public Health Published on 2020-06-042022-08-31 Journal: Frontiers in Public Health [Category] MERS, SARS, 진단, 치료기술, [키워드] accompanied adopted Autopsy clinical information common sense coronavirus coronavirus disease COVID-19 Department disease healthcare healthcare worker Healthcare workers highly pathogenic hot spot infectious information involved Italian learning lombardy management mandatory National National Health Service outbreak pathologist Pathologists pathology Patient Policy Post-mortem receive reduce reported resident Safety smart work specimen status surgical tissue samples Viral viral infection Viral load WHO guidelines [DOI] 10.3389/fpubh.2020.00259 PMC 바로가기 [Article Type] Public Health
SARS-CoV-2 SPIKE PROTEIN: an optimal immunological target for vaccinesCommentary Published on 2020-06-032022-10-30 Journal: Journal of Translational Medicine [Category] COVID-19, SARS, [키워드] adopted COVID-19 effective effort Evidence immunological immunotherapies MERS pandemic Protein Research SARS-CoV-2 Spike protein Spread target the Spike Vaccine [DOI] 10.1186/s12967-020-02392-y PMC 바로가기 [Article Type] Commentary
Learning from the Italian experience in coping with COVID-19Short Communication Published on 2020-06-032022-10-28 Journal: Revista da Sociedade Brasileira de Medicina Tropic [Category] COVID-19, MERS, SARS, [키워드] adopted article Brazil cause country COVID-19 COVID-19 case early stage effective Epidemic health system Italian Italian region Italy learning measure pandemic Patient rapid increase reduce SARS-CoV-2 social isolation Spread Support the epidemic with COVID-19 worsening [DOI] 10.1590/0037-8682-0199-2020 PMC 바로가기 [Article Type] Short Communication