A Meta-Analysis of the Efficacy of Interferon Monotherapy or Combined with Different Nucleos(t)ide Analogues for Chronic Hepatitis BArticle Published on 2016-07-212023-06-03 Journal: International Journal of Environmental Research an [Category] B형 간염, [키워드] Chronic Hepatitis B combination therapy interferon Meta-analysis nucleos(t)ide analogues [DOI] 10.3390/ijerph13070730 PMC 바로가기 [Article Type] Article
Prevention of hepatitis B virus-associated liver diseases by antiviral therapyReview Published on 2016-07-012023-06-18 Journal: Hepatology international [Category] B형 간염, [키워드] Chronic Hepatitis B HCC interferon Nucleos(t)ide analogue [DOI] 10.1007/s12072-016-9720-y [Article Type] Review
[Management and treatment of patients with hepatitis B]Review Published on 2016-07-012023-06-18 Journal: Enferm Infecc Microbiol Clin [Category] B형 간염, [키워드] Carcinoma hepatocelular Chronic Hepatitis B Cirrosis hepática entecavir Hepatitis B crónica Hepatocellular carcinoma Inferferon interferon Liver cirrhosis tenofovir Tratamiento Treatment [DOI] 10.1016/S0213-005X(16)30219-1 [Article Type] Review
Viral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-AntagonistsReview Published on 2016-06-292024-09-02 Journal: Vaccines [Category] 대상포진, [키워드] immune evasion Innate immunity interferon JAK/STAT pathway Vaccines viruses [DOI] 10.3390/vaccines4030023 PMC 바로가기 [Article Type] Review
Dynamics of in vivo hepatitis D virus infectionArticle Published on 2016-06-072023-06-16 Journal: Journal of theoretical biology [Category] B형 간염, [키워드] Hepatitis-B virus interferon mathematical model Pathogenesis Prenylation. [DOI] 10.1016/j.jtbi.2016.03.018
Immune evasion of porcine enteric coronaviruses and viral modulation of antiviral innate signalingReview Published on 2016-05-192022-11-01 Journal: Virus research [Category] Coronavirus, MERS, [키워드] Antiviral antiviral cytokine Antiviral innate signaling appear coronavirus diarrhea enteric Enteric coronavirus epidemic diarrhea epithelial epithelial cell epithelial cells Evidence feature gastroenteritis Gut high mortality Host host innate immunity IFN IFN antagonist IFN-α/β IFN-λ immune evasion infect Infection innate immune Innate immunity interferon Interferon regulation intestinal intestinal epithelia intestinal epithelial cell maintain modulate modulation mucosal surface Neonatal nsp1 PEDV Porcine deltacoronavirus Porcine epidemic diarrhea virus Signaling small intestine TGEV These viruses turn Type Type III IFN type III interferon virus viruses watery [DOI] 10.1016/j.virusres.2016.05.015 PMC 바로가기 [Article Type] Review
Tfh cell-mediated humoral immune response and HBsAg level can predict HBeAg seroconversion in chronic hepatitis B patients receiving peginterferon-α therapyArticle Published on 2016-05-012023-06-18 Journal: Molecular immunology [Category] B형 간염, [키워드] B cells Follicular T helper cells HBeAg seroconversion Hepatitis B virus interferon [DOI] 10.1016/j.molimm.2016.03.011
Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3Original Article Published on 2016-04-202022-10-31 Journal: Emerging Microbes & Infections [Category] Coronavirus, [키워드] Activation antiviral response association C-terminal C-terminal domain characterized chimeric claimed conserved contribute evade ex vivo models expression highly pathogenic Host IFN induce infected patient Infection inhibitory effect innate antiviral response interferon IRF3 IRF3 activation M protein mechanism MERS coronavirus MERS-CoV Middle East mutants N-terminal nuclear Pathogenesis Phosphorylation Protein reduced Regulatory respiratory syndrome coronavirus resulting RIG-I-like receptors SARS-CoV Saudi Arabia Sendai virus suppress suppresse suppressed TRAF3 transmembrane domain Type I IFN type I interferon type I interferons [DOI] 10.1038/emi.2016.33 PMC 바로가기 [Article Type] Original Article
Optineurin deficiency in mice is associated with increased sensitivity to Salmonella but does not affect proinflammatory NF‐κB signaling마우스에서 옵티뉴린 결핍은 살모넬라에 대한 민감도 증가와 관련이 있지만, 염증성 NF-κB 신호전달에는 영향을 미치지 않습니다.journal-article Published on 2016-04-012024-07-30 Journal: Neurogastroenterology and motility : the official [Category] 살모넬라증, [키워드] autophagy Inflammation Innate immunity interferon NF-κB Optineurin. [DOI] 10.1002/eji.201545863 [Article Type] journal-article
Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L ActivationResearch Article Published on 2016-03-292022-10-29 Journal: mBio [Category] Coronavirus, [키워드] accessory protein activate Activation acute respiratory syndrome antiviral activity Betacoronavirus calu-3 cells cell death characterized cleave contribute coronavirus Coronaviruses CoV Critical cytoplasmic dsRNA enzyme expressed expression level genes encoding Genome highly pathogenic homolog Host host antiviral response host innate immunity IFN IFN signaling in vivo model inactivation Infection Innate immunity interferon involved Like Lineage mechanism MERS MERS-CoV MERS-CoV infection Middle East murine mutant NLS NS2 NS4b nuclear localization signal nucleus offer other coronaviruses Pathogenesis pathway potential mechanism Prevent Protein provide Replication reported required respiratory respiratory syndrome coronavirus RNA RNase SARS-CoV single-stranded Spread ssRNA subsequent therapeutic intervention translational type I interferon viral double-stranded RNA viral pathogenesis viral replication virulence [DOI] 10.1128/mBio.00258-16 PMC 바로가기 [Article Type] Research Article