Immunostimulation in the era of the metagenomeReview Published on 2011-05-312024-09-04 Journal: Cellular and Molecular Immunology [Category] 대상포진, [키워드] antimicrobial peptides Autoimmune disease immune reconstitution inflammatory syndrome immunopathology Innate immunity metagenomics [DOI] 10.1038/cmi.2010.77 PMC 바로가기 [Article Type] Review
Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 ComplexResearch Article Published on 2011-05-262022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, [키워드] 2003 activating Activation antiviral drug assay association atomic resolution Author bind binding binding pocket CAP chromatin complex coronavirus crystal crystal structures disease enzyme etiological agent exhibit functional Genome Giant host cell identify inhibitor Innate immunity involved mechanism metabolism methyltransferase mRNA mutant non-structural protein Novel coronavirus nucleic acid performed Protein provide regulated Regulation replicate residue respiratory resulting RNA S-adenosylmethionine SAM severe Signal transduction stability Structure translation viruses [DOI] 10.1371/journal.ppat.1002059 PMC 바로가기 [Article Type] Research Article
A Decline in p38 MAPK Signaling Underlies Immunosenescence in Caenorhabditis elegansCaenorhabditis elegans에서 p38 MAPK 신호 전달의 감소는 면역 노화의 기초가 됩니다Research Article Published on 2011-05-192022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] addressed age aging amplify Author Bacteria Bacterial Bacterial infection Caenorhabditis Caenorhabditis elegan Caenorhabditis elegans change conserved cycle death Decline declines Defense defined Deterioration elegan examined exhibit Genetic Host host defense human pathogen humans immune function immunosenescence impair implicated increase in Infection innate immune Innate immunity intestinal intestinal tissue involved leads MAPK mice mitogen mitogen-activated protein kinase molecular basis molecular mechanism motion pathogen pathway phenomenon PMK-1 proliferation promote Protein protein kinase Pseudomonas aeruginosa regulate signaling pathway susceptibility tissue damage turn [DOI] 10.1371/journal.pgen.1002082 PMC 바로가기 [Article Type] Research Article
Innate immunity and monocyte-macrophage activation in atherosclerosisReview Published on 2011-04-282023-08-30 Journal: Journal of Inflammation (London, England) [Category] E형 간염, [키워드] Atherosclerosis Inflammation Innate immunity Macrophage polarisation Macrophage subtypes monocyte subsets Toll-like receptors [DOI] 10.1186/1476-9255-8-9 PMC 바로가기 [Article Type] Review
Ribose 2′- O -methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5Article Published on 2011-01-092023-06-15 Journal: Nature Immunology [Category] Fulltext, MERS, [키워드] Innate immunity RNA modification Virus-host interactions [DOI] 10.1038/ni.1979 PMC 바로가기 [Article Type] Article
Strain variation in early innate cytokine induction by Plasmodium falciparum플라스모디움 팔시파룸에 의한 초기 선천성 사이토카인 유도의 균주 변이Original Article Published on 2010-07-012024-08-26 Journal: Parasite Immunology [Category] 말라리아, [키워드] Innate immunity Interferonᵧ malaria virulence [DOI] 10.1111/j.1365-3024.2010.01225.x PMC 바로가기 [Article Type] Original Article
SARS-CoV Pathogenesis Is Regulated by a STAT1 Dependent but a Type I, II and III Interferon Receptor Independent MechanismResearch Article Published on 2010-04-082022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] acute lung injury acute respiratory syndrome affecting alveolar inflammation ARDS Author BALB/c mice caused cell proliferation clinical disease coronavirus death demonstrated Dependent died Diffuse alveolar damage ENhance Epidemic evaluated highly pathogenic I, II independent Infected Infection innate immune innate immune response Innate immunity interferon interferon signaling knockout mice lack liver Lung disease Lung injury Lung pathology MA15 mechanism mice molecular mechanism Mortality Mouse models other tissue outcomes Pathogenesis Pathways Post-infection PROTECT Protein pulmonary fibrosis pulmonary lesion question receptor regulated respiratory respiratory virus SARS Coronavirus SARS pathogenesis SARS-CoV SARS-CoV infection severe severe disease Signaling spleen Stat1 the epidemic Type type I type III interferon viral pathogenesis virus virus pathogenesis virus titer Virus-host interaction viruses weight loss wildtype [DOI] 10.1371/journal.ppat.1000849 PMC 바로가기 [Article Type] Research Article
A new paradigm of bacteria-gut interplay brought through the study of Shigella시겔라 연구를 통해 밝혀진 새로운 세균-장 상호작용 패러다임Review Published on 2010-03-012024-08-21 Journal: Proceedings of the Japan Academy. Series B, Physical and Biological Sciences [Category] 세균성이질, [키워드] epithelial cells Infection Innate immunity pathogenicity Shigella Shigellosis [DOI] 10.2183/pjab.86.229 PMC 바로가기 [Article Type] Review
Antagonism of Innate Immunity by Paramyxovirus Accessory ProteinsReview Published on 2009-12-282023-08-29 Journal: Viruses [Category] E형 간염, [키워드] Apoptosis Innate immunity interferon paramyxoviruses [DOI] 10.3390/v1030574 PMC 바로가기 [Article Type] Review
Characterization of the cytokine and maturation responses of pure populations of porcine plasmacytoid dendritic cells to porcine viruses and toll-like receptor agonistsArticle Published on 2009-10-302023-06-15 Journal: Veterinary Immunology and Immunopathology [Category] MERS, [키워드] FACS Immunity Innate immunity interferon-α plasmacytoid dendritic cell PRRs Vaccine [DOI] 10.1016/j.vetimm.2009.10.026 PMC 바로가기 [Article Type] Article