SARS-CoV-2 variants – Page 108 – Communicable Diseases Research

Prolonged evolution of the human B cell response to SARS-CoV-2 infection

SARS-CoV-2 감염에 대한 인간 B 세포 반응의 연장된 진화

Research Articles

Published on 2021-02-232022-09-10
Journal: Science Immunology
[Category] Fulltext, MERS, 변종, 진단,

Are the emerging SARS-COV-2 mutations friend or foe?

새로운 SARS-COV-2 돌연변이는 친구입니까, 적입니까?

Article

Published on 2021-02-012022-09-11
Journal: Immunology letters
[Category] 변종,

[키워드] conformation current Epitopes immunogenicity Mutation N501Y open SARS-CoV-2 variant SARS-CoV-2 variants Spike protein the spike protein Transmissibility virus
[DOI] 10.1016/j.imlet.2020.12.014 PMC 바로가기 [Article Type] Article

Two-step strategy for the identification of SARS-CoV-2 variant of concern 202012/01 and other variants with spike deletion H69–V70, France, August to December 2020

2020년 8월~12월 프랑스, 스파이크 결실 H69–V70이 있는 우려되는 SARS-CoV-2 변이체 및 기타 변이체 식별을 위한 2단계 전략 202012/01

Rapid Communication

Published on 2021-01-212022-09-10
Journal: Eurosurveillance
[Category] 변종, 치료기술, 치료제,

[키워드] approach COVID-19, whole genome sequencing France Mutation N501Y other variant PCR assay RT-PCR assay S-gene SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants screened sequenced spike protein, variants, deletion TaqPath variant VoC whole genome
[DOI] 10.2807/1560-7917.ES.2021.26.3.2100008 PMC 바로가기 [Article Type] Rapid Communication

SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells

S1/S2 절단 부위에 돌연변이가 있는 SARS-CoV-2 변이체는 TMPRSS2 결핍 세포에서 증식하는 동안 시험관 내에서 생성됩니다

Research Article

Published on 2021-01-212022-08-13
Journal: PLoS Pathogens
[Category] Biochemistry, COVID-19,

[키워드] alteration antivirals bind Cell cell lines cell tropism cleavage cleavage site cleaved Coronaviruses Critical de novo demonstrated direct fusion dominant entry pathway exhibited experiments facilitate generate Host host cell host cell receptor host protease in vitro inefficient infect motif mutant mutants Mutation performed plaque plaques polybasic Protein proteolytic cleavage researcher respiratory S gene S protein S1/S2 cleavage site SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 propagation SARS-CoV-2 S gene SARS-CoV-2 variant SARS-CoV-2 variants screened Serine Severe acute respiratory syndrome severe acute respiratory syndrome-coronavirus-2 shown target cells the cell the S protein TMPRSS2 transmembrane serine protease Transmissibility type strain undergo Vaccine variant Vero Cell Vero cells Viral viral entry virus virus virus strains virus variants viruses wild-type strain
[DOI] 10.1371/journal.ppat.1009233 PMC 바로가기 [Article Type] Research Article

Genomic surveillance of Nevada patients revealed prevalence of unique SARS-CoV-2 variants bearing mutations in the RdRp gene

네바다 환자의 게놈 감시는 RdRp 유전자에 돌연변이가 있는 독특한 SARS-CoV-2 변이체의 유행을 나타냈습니다

Article

Published on 2021-01-202022-09-11
Journal: Journal of genetics and genomics = Yi chuan xue ba
[Category] 변종,

[키워드] accessory protein accessory proteins amplification association changed circulating circulation Community COVID-19 COVID-19 patient Culture determine diagnostic domain Evolution Frequency genome coverage Genome enrichment Genomic surveillance geographic locations humans Mutation Nsp12 Occurrence ORF1b orf1b 314. other variant other variants outbreak Patient Phenylalanine Phylogenetic relationship platform polymerase Prevalence proline public health RdRP RdRp gene reported required RNA RNA-dependent RNA polymerase robust RT-PCR SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sequenced Sequencing specimen swabs tested unique variant variants variants of SARS-CoV-2 Viral viral loads Wuhan-Hu-1
[DOI] 10.1016/j.jgg.2021.01.004 PMC 바로가기 [Article Type] Article

A human antibody of potent efficacy against SARS-CoV-2 in rhesus macaques showed strong blocking activity to B.1.351

붉은 털 원숭이에서 SARS-CoV-2에 대한 강력한 효능의 인간 항체는 B.1.351에 대한 강력한 차단 활성을 나타냈습니다

Article

Published on 2021-01-012022-09-11
Journal: mAbs
[Category] MERS, 변종, 진단, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 antibody B.1.1.7 B.1.351 binding blocking activity broad-spectrum cause clinical trial Complete convalescent plasma coronavirus coronavirus disease coronavirus disease-2019 Coronavirus-2 COVID-19 COVID-19 pandemic D614G demonstrated disease Efficacy hACE2 host cell host cell receptor in vitro Infection interact Intervention JMB2002 lead neutralization Neutralizing Neutralizing antibodies neutralizing antibody phage phage-to-yeast Phase 1 Phase 1 clinical trial platform Prophylactic Protein RBD Receptor binding domain respiratory rhesus rhesus macaque rhesus macaque disease model. SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sequence sera Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 the RBD the SARS-CoV-2 therapeutic therapeutic efficacy Transmission Vaccine virus yeast
[DOI] 10.1080/19420862.2021.1930636 PMC 바로가기 [Article Type] Article

The SARS-CoV-2 ORF10 is not essential in vitro or in vivo in humans

SARS-CoV-2 ORF10은 인간의 시험관 내 또는 생체 내에서 필수적이지 않습니다.

Research Article

Published on 2020-12-102022-08-13
Journal: PLoS Pathogens
[Category] MERS, SARS, 변종, 유전자 메커니즘,

[키워드] accessory proteins analyses annotation appear Author can not coding region debate described disease downstream Evidence expressed expression Genome genomic genomic sequence Human humans hypothetical hypothetical protein in vitro in vitro study in vivo include infected with SARS-CoV-2 Initially Innate immunity Laboratory laboratory analyses mRNA mRNAs N gene observation Open reading frame open reading frames ORF10 ORF10 protein ORFs Pathogenesis Patient positioned produced Protein protein-coding gene Proteins related virus related viruses replicated Replication required SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 variant SARS-CoV-2 variants sequence homology sequence similarity strain Strains structural protein structural proteins subgenomic mRNA subgenomic mRNAs the SARS-CoV-2 genome Transmissibility treated two patients variant Viral Viral proteins viruses while
[DOI] 10.1371/journal.ppat.1008959 PMC 바로가기 [Article Type] Research Article

SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity

SARS-CoV-2 스파이크 단백질 D614G 돌연변이는 비리온 스파이크 밀도와 감염성을 증가시킵니다.

Article

Published on 2020-11-262022-09-10
Journal: Nature Communications
[Category] SARS, 변종,

Point mutation bias in SARS-CoV-2 variants results in increased ability to stimulate inflammatory responses

Article

Published on 2020-10-202022-10-04
Journal: Scientific Reports
[Category] MERS, SARS, 변종,