Sensitive and Specific Detection of SARS-CoV-2 Antibodies Using a High-Throughput, Fully Automated Liquid-Handling Robotic System처리량이 완전 자동화된 액체 처리 로봇 시스템을 사용한 SARS-CoV-2 항체의 민감하고 특이적인 검출Original Research Published on 2020-08-202022-09-01 Journal: Slas Technology [Category] MERS, SARS, 진단, 치료기술, [키워드] addition agglutination analyst anti–spike protein antibody Antibody detection Antigen automated battle can be used Community Contact contact with control patient Coronaviral coronavirus disease Coronavirus disease 2019 CoV-NL63 COVID-19 cross-react detection generate global pandemic helping immune complex immunoassay individual infected patients Infection infection prevalence infections liquid handling pandemic Patient PCR PCR-confirmed COVID-19 patient platform probe protocol qualitative detection quarantine reduce responsible SARS-CoV-2 sensitive sensitivity serological assays serum Specific specificity Spike protein STAR System tested total antibodies total antibody Treatment virus [DOI] 10.1177/2472630320950663 PMC 바로가기 [Article Type] Original Research
Single Cell RNA-seq Data Analysis Reveals the Potential Risk of SARS-CoV-2 Infection Among Different Respiratory System ConditionsGenetics Published on 2020-08-202022-10-31 Journal: Frontiers in Genetics [Category] COVID-19, [키워드] ACE2 Analysis AT2 cancers Cell cell type collected condition conditions contribute COVID-19 COVID-19 infection disease expression FIVE help higher risk increase in increased risk Infection infection risk IPF lower expression lower risk lung lung cancer lung cells pandemic Patient Potential potential risk predict Prevent profiles pulmonary fibrosis required respiratory Respiratory system resulting risk RNA-Seq SARS-CoV-2 severity single cell transcriptome single-cell smoking System tissue TMPRSS2 TMPRSS2 expression transcriptome datasets understanding [DOI] 10.3389/fgene.2020.00942 PMC 바로가기 [Article Type] Genetics
Can Air-Conditioning Systems Contribute to the Spread of SARS/MERS/COVID-19 Infection? Insights from a Rapid Review of the LiteratureReview Published on 2020-08-202022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] adopted agency Airborne transmission Asian Can carried Conditioning Contamination coronavirus Coronavirus infection COVID-19 demonstrated diffusion East English evaluate Evidence Google Scholar Heating insight International limit literature MERS MERS-CoV organization original outbreak Outbreaks PMC Prevent prevention PubMed Central Rapid released review risk Safety SARS-CoV SARS-CoV-1 SARS-CoV-2 Seven Spread supported System the SARS-CoV-2 virus Transmission transmission of SARS-CoV-2 transmitted Ventilation viral particle Workplace [DOI] 10.3390/ijerph17176052 PMC 바로가기 [Article Type] Review
Impact of Wearing Masks, Hand Hygiene, and Social Distancing on Influenza, Enterovirus, and All-Cause Pneumonia During the Coronavirus Pandemic: Retrospective National Epidemiological Surveillance StudyOriginal Paper Published on 2020-08-202022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, [키워드] Analysis contribute coronavirus disease COVID-19 COVID-19 pandemic database decrease disease Diseases enterovirus enterovirus infection epidemiological hand Health hygiene Impact incidence Influenza Influenza virus linear regression analyses Masks National Novel coronavirus objective pandemic performed Pneumonia prevention prevention of COVID-19 produced promoted R 2 Regression reported Result SARS-CoV-2 significant decrease social distancing Statistics Surveillance System Taiwan viral infection wearing wearing masks [DOI] 10.2196/21257 PMC 바로가기 [Article Type] Original Paper
Separating the wheat from the chaff—COVID-19 in a German emergency department: a case-control studyOriginal Research Published on 2020-08-202022-10-30 Journal: International Journal of Emergency Medicine [Category] COVID-19, [키워드] case-control study categories clinical Clinical parameters clinical symptom Clinical symptoms clinically conducted COVID-19 COVID-19 patient COVID-19 patients cross disease dysgeusia emergency department Essen health care systems Inpatient Isolation lab Laboratory maintain majority management Mild symptom Nasopharyngeal swab negative test occurred other disease outpatients Pandemia parameter Patient patients with COVID-19 positive presenting Result Retrospective analysis Safe SARS-CoV-2 significantly more Symptom Symptoms symptoms of COVID-19 System tested treated Triage university hospital variety [DOI] 10.1186/s12245-020-00302-z PMC 바로가기 [Article Type] Original Research
Evaluation of the Usefulness of CO-RADS for Chest CT in Patients Suspected of Having COVID-19Article Published on 2020-08-192022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] age AUC average calculated characteristic Chest computed tomography Chest CT Chest CT images chest imaging clinically suspected CO-RADS Computed tomography COVID-19 diagnostic evaluate evaluated ICC Intraclass correlation coefficient investigated lung involvement male no significant difference Patient Pneumonia positive provide radiologist Radiologists radiology Reporting RT-PCR sensitivity Society specificity Suspected System the median [DOI] 10.3390/diagnostics10090608 PMC 바로가기 [Article Type] Article
COVID-19 Mortality Underreporting in Brazil: Analysis of Data From Government Internet PortalsOriginal Paper Published on 2020-08-182022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, [키워드] acute respiratory syndrome affected Analysis analyzed average Brazil build carried cause coronavirus disease country COVID-19 death deaths Department effective Epidemic expected mortality expected values fatality Forecasting Government identify increase individual informatics Internet Mortality much lower number of infected objective official pandemic portal predict public health Registered registry regressions released reported respiratory problem respiratory system diseases Result significant difference Spread System the disease Time series Transparency Underreporting used data were used worsening [DOI] 10.2196/21413 PMC 바로가기 [Article Type] Original Paper
Renin-Angiotensin System overactivation in polycystic ovary syndrome, a risk for SARS-CoV-2 infection?Original Research Paper Published on 2020-08-182022-10-31 Journal: Metabolism Open [Category] COVID-19, [키워드] ACE2 ACE2 protein age angiotensin-converting enzyme 2 angiotensinogen aptamer blood pressure blood vessels BMI Cell Cohort condition COVID-19 infection CRP described diabete diastolic elevated high risk hypertension independent inherent insulin resistance intestines kidneys Lungs obesity plasma Plasma level plasma protein Polycystic ovary syndrome Protein RAS receptor Renin Result risk SARS-CoV-2 SARS-CoV-2 coronavirus Severe COVID-19 Infection severe disease slow syndrome System T2D target cell Type type 2 diabete Waist circumference women [DOI] 10.1016/j.metop.2020.100052 PMC 바로가기 [Article Type] Original Research Paper
Does activation of the protective Renin-Angiotensin System have therapeutic potential in COVID-19?Hypothesis Published on 2020-08-172022-10-30 Journal: Molecular Medicine [Category] COVID-19, MERS, [키워드] ACE2 Activation acute respiratory distress addition agonist angiotensin ARDS AT1R AT2R cause contribute COVID-19 COVID-19 patients disease edema end-organ damage Inflammation lung cell MasR Medicine molecular Pathogenesis Protective pulmonary dysfunction receptor reduce syndrome System therapeutic potential treat virus [DOI] 10.1186/s10020-020-00211-0 PMC 바로가기 [Article Type] Hypothesis
Impact of two-level filtering on emergency medical communication center triage during the COVID-19 pandemic: an uncontrolled before-after studyOriginal Research Published on 2020-08-142022-10-29 Journal: Scandinavian Journal of Trauma, Resuscitation and [Category] Coronavirus, MERS, [키워드] Accessibility adjusted Analysis analyzed average bystander condition conditions conducted confounding variables COVID-19 COVID-19 outbreak COVID-19 pandemic described disease Emergency medical communication center excluded highlighting identify Impact information Linear regression model maintaining Nantes University Hospital outbreak outcome measure potentially life-threatening Primary outcome Prospective Study Rapid reduce required resources Result significant increase significantly increased System this system transferred Triage [DOI] 10.1186/s13049-020-00775-0 PMC 바로가기 [Article Type] Original Research