Identification and characterization of novel RdRp and Nsp15 inhibitors for SARS-COV2 using computational approach컴퓨터 접근 방식을 사용한 SARS-COV2에 대한 새로운 RdRp 및 Nsp15 억제제의 식별 및 특성화Article Published on 2022-04-012022-09-11 Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, 신약개발, 치료제, [키워드] active site acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alectinib approach caused Compound coronavirus COVID-19 COVID19 different disease different diseases drug Drug repurposing effective inhibitor EndoU enzyme Ergotamine health emergency Health Organization highlight homology homology modeling hydrogen Hydrogen bond hydrophobic identification inhibitor inhibitors Interaction MD simulation molecular molecular interaction molecular mimicry Naldemedine Nsp15 observé pathogen performed Protein target RdRP residue RNA RNA dependent RNA polymerase RNA polymerase SARS-CoV-2 selected severe acute respiratory syndrome Coronavirus Therapeutics Virtual screening were used World Health Organization [DOI] 10.1080/07391102.2020.1841026 PMC 바로가기 [Article Type] Article
Assessment of the clinical and laboratorial profile of patients with obesity and asymptomatic COVID-19 undergoing bariatric surgery in Brazil브라질에서 비만 수술을 받은 무증상 COVID-19 환자의 임상 및 실험실 프로필 평가Article Published on 2022-04-012022-09-11 Journal: Obesity surgery [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 age assessment Asymptomatic case Asymptomatic cases Asymptomatic COVID-19 Bariatric surgery BMI body mass body mass index Brazil C-reactive protein Case series Chain Reaction collected Complication Coronavirus-2 COVID19 demographic characteristics Dengue dengue virus diabete diabetes Diagnosis disease severity elapsed ferritin FIVE Hospital stay hypertension IgG incidence inflammatory markers Laboratory lymphocyte Lymphocytes marker Micronutrient micronutrients obesity operation Patient patients with obesity polymerase chain reaction positive positive RT-PCR postoperative Postoperative Complications Preoperative period previous diagnosis reported reported symptoms RT-PCR serology serum Serum level serum levels Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Sleeve Sleeve gastrectomy study period surgery tested the mean Vitamin D without symptom women Zinc [DOI] 10.1007/s11695-022-05891-7 PMC 바로가기 [Article Type] Article
Differences in COVID-19-Related Testing and Healthcare Utilization by Race and Ethnicity in the Veterans Health AdministrationArticle Published on 2022-04-012023-07-06 Journal: Journal of racial and ethnic health disparities [Category] COVID19(2023년), [키워드] COVID19 disparity Prevalence veteran [DOI] 10.1007/s40615-021-00982-0 PMC 바로가기
Specific changes of erythroid regulators and hepcidin in patients infected by SARS-COV-2Observational Study Published on 2022-04-012022-10-05 Journal: Journal of investigative medicine : the official p [Category] COVID19(2023년), SARS, 임상, [키워드] both groups C reactive protein change Concentration COVID-19 COVID19 defined described ERFE evaluate ferritin growth hematological parameters Inflammation inflammatory signal involved IQR iron iron homeostasis median metabolism Patient patients with COVID-19 performed plasma positive RT-PCR Protein receptor Regulatory SARS-CoV-2 SARS-COV-2 infection Sepsis single-center Specific statistically Transferrin [DOI] 10.1136/jim-2021-002270 PMC 바로가기 [Article Type] Observational Study
Adverse events reported after administration of BNT162b2 and mRNA-1273 COVID-19 vaccines among hospital workers: a cross-sectional survey-based study in a Spanish hospitalArticle Published on 2022-04-012023-07-07 Journal: Expert review of vaccines [Category] COVID19(2023년), [키워드] adverse events BNT162b2 COVID19 mRNA-1273 Vaccine [DOI] 10.1080/14760584.2022.2022478 PMC 바로가기
Novel T cell interferon gamma release assay (IGRA) using spike recombinant protein for COVID19 vaccine response and Nucleocapsid for SARS-Cov2 responseArticle Published on 2022-04-012023-06-19 Journal: Clinical immunology (Orlando, Fla.) [Category] COVID19(2023년), MERS, SARS, [키워드] COVID19 spike T cell response Vaccine [DOI] 10.1016/j.clim.2022.108979 PMC 바로가기
Long Lasting Cellular Immune Response Induced by mRNA Vaccination: Implication for Prevention StrategiesmRNA 백신 접종으로 유도된 오래 지속되는 세포 면역 반응: 예방 전략에 대한 시사점Article Published on 2022-03-102022-09-12 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, [키워드] Administered B lymphocyte B lymphocytes BNT162b2 BNT162b2 mRNA CD4+ CD8+ T lymphocytes Cellular immune response Control COVID-19 COVID-19 vaccine COVID19 evaluated Frequency healthcare worker immune response immunized in vitro induce induced Long mRNA mRNA vaccination pandemic peptides prevention required respond response SARS-CoV2 second dose spike Spread Strategy subjects T lymphocyte T lymphocytes activation to define vaccination Vaccination strategies Vaccine [DOI] 10.3389/fimmu.2022.836495 PMC 바로가기 [Article Type] Article
Unvaccinated Children Are an Important Link in the Transmission of SARS-CoV-2 Delta Variant (B1.617.2): Comparative Clinical Evidence From a Recent Community Surge백신을 접종하지 않은 어린이는 SARS-CoV-2 델타 변이형(B1.617.2) 전파의 중요한 연결 고리: 최근 커뮤니티 급증의 비교 임상 증거Article Published on 2022-03-082022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 변종, 진단, [키워드] accounted Admission antibody B.1.167.2 B.1.617.2 children China clinical Clinical characteristics Clinical data Clinical features Comparative Contact convalescence cough COVID COVID 19 COVID-19 vaccination COVID19 CRP Delta delta variant Delta variants enrolled evaluate examined Factor Fever IgG IgM and IgG IL-6 IL-6 level indicated less lymphocyte Lymphocyte count nucleic acid Patient PCR positivity Peripheral blood peripheral blood lymphocyte counts R statistical analysis recent reported SARS-CoV-2 School Schools Sequencing Spread statistical analysis Transmission transmission of SARS-CoV-2 two group two groups vaccination variant [DOI] 10.3389/fcimb.2022.814782 PMC 바로가기 [Article Type] Article
Evaluating e-health literacy, knowledge, attitude and practice regarding COVID-19 prevention and Self-Protection among Iranian students: a cross-sectional online surveyResearch Published on 2022-03-052022-10-28 Journal: BMC Medical Education [Category] COVID-19, MERS, SARS, [키워드] analyzed Attitude conducted Coronavirus 19 Coronavirus 2019 COVID-19 COVID19 cross-sectional demographic characteristics disease E-health literacy Evaluating female female gender Government identify IMPROVE individuals information interquartile range Intervention IQR KAP knowledge literacy median median age Older age pandemic participated Practice predictor prevention Preventive behavior questionnaire Result scale significantly higher SPSS software university student [DOI] 10.1186/s12909-022-03210-3 PMC 바로가기 [Article Type] Research
Normal pressure hydrocephalus associated with COVID-19 infection: a case reportCase Report Published on 2022-03-032022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] abnormality association Case report Cell Cognitive impairment Complete coronavirus COVID COVID-19 COVID19 CSF cytokine release death Dementia described disorder Hospitalized hypercoagulability include Infection Lyme disease male mechanism MRI Neuroinflammation neurologic manifestations neurological manifestation Normal pressure hydrocephalus NPH Other pandemic disease Patient positive resolution of symptoms responsible Risk factors SARS-CoV-2 SARS-COV-2 infection spinal tap venous viral invasion with COVID-19 [DOI] 10.1186/s12879-022-07184-x PMC 바로가기 [Article Type] Case Report