Virus transmission by ultrasonic scaler and its prevention by antiviral agent: An in vitro study초음파 스케일러에 의한 바이러스 전파 및 항바이러스제에 의한 예방: 시험관 내 연구Article Published on 2022-07-012022-09-11 Journal: Journal of periodontology [Category] 치료기술, 치료제, [키워드] adherent antimicrobial(s) Antiviral antiviral activity antiviral agent Antiviral agents Bacteria Cell cell line changed collected Concentration coolant COVID-19 pandemic Culture Cytopathic effect dental procedures Detection limit develop distance droplet droplets evaluate evaluated in vitro study infected cells Infection infection control Infection transmission Microbiology mitigate non-surgical periodontal therapy number of infected oxidizing Spread Suspension Transmission ultrasonic scaler viral particle Viral particles Virology virus virus transmission viruses was tested water [DOI] 10.1002/JPER.21-0335 PMC 바로가기 [Article Type] Article
COVID-19 diagnostic methods in developing countries개발 도상국의 COVID-19 진단 방법Review Published on 2022-07-012022-09-11 Journal: Environmental science and pollution research inter [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] Accuracy acute respiratory syndrome coronavirus addition Antigen Antiviral agents antiviral medication Antiviral medications carried cause caused chance clinical trial clinical trials clinically Combination coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 country COVID-19 COVID-19 test COVID-19 testing COVID-19 vaccines death Diagnostic method disease disrupt effort ELIZA Epidemic immune Immunity Invasion Laboratory lack life Mutation omicron pandemic Patient patients Prevent resource respiratory respiratory syndrome coronavirus 2 risk RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 SHERLOCK Spread the SARS-CoV-2 virus the vaccine thought time-consuming vaccination Vaccine Vaccine development variant viral invasion [DOI] 10.1007/s11356-022-21041-z PMC 바로가기 [Article Type] Review
Repurposing drugs targeting epidemic virusesReview article Published on 2022-07-012022-10-05 Journal: Drug discovery today [Category] 신약개발, [키워드] Antiviral agents antiviral drug antiviral drugs approach biological response broad-spectrum antiviral candidate clinical trials develop Drug discovery Drug repurposing drug resistance drugs targeting Epidemic Epidemic virus infections reducing repurposing researcher viral infectious diseases virus [DOI] 10.1016/j.drudis.2022.04.008 [Article Type] Review article
Virtual and biochemical screening to identify the inhibitors of binding between SARS-CoV-2 spike protein and human angiotensin-converting enzyme 2SARS-CoV-2 스파이크 단백질과 인간 안지오텐신 전환 효소 2 간의 결합 억제제를 식별하기 위한 가상 및 생화학적 스크리닝Article Published on 2022-07-012022-09-11 Journal: Journal of molecular graphics & modelling [Category] COVID19(2023년), SARS, 치료제, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus addressed Analysis angiotensin antiviral activity Antiviral agents antiviral medicine assays binding biochemical caused Chemotherapy coronavirus COVID-19 COVID-19 pandemic Critical drug candidate effective glycosylated host cell human ACE2 human Angiotensin-converting enzyme Human angiotensin-converting enzyme 2 identify in vitro inhibitor Interaction interaction pattern interaction patterns low molecular weight moderate physicochemical property Protein S-protein SARS-CoV-2 SARS-CoV-2 spike protein severe acute respiratory syndrome Coronavirus spike Spike protein therapeutic target Treatment treatment of COVID-19 viral pathogen Virtual screening [DOI] 10.1016/j.jmgm.2022.108206 PMC 바로가기 [Article Type] Article
Advances in the Omicron variant developmentOmicron 변종 개발의 발전Review Published on 2022-07-012022-09-11 Journal: Journal of internal medicine [Category] COVID19(2023년), SARS, 변종, 진단, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus addition advance Alpha Amino acid amino acids Antiviral antiviral agent Antiviral agents antiviral drugs approved Beta booster dose booster doses Casirivimab circulating coronavirus COVID-19 Delta disease dominant dose drug effective entry of SARS-CoV-2 Epidemiology epitope Epitopes Gamma greater greater transmissibility growth advantage Health Organization humoral Imdevimab Immune escape incidence Infection inhibit Mild mild illness molecular molnupiravir monoclonal monoclonal antibodies monoclonal antibody mutations offer omicron Omicron variant pandemic Paxlovid pharmacological agent pharmacological agents Remdesivir Research respiratory SARS-CoV-2 SARS-CoV-2 virus severe acute respiratory syndrome Coronavirus Spike protein Spread the spike protein therapeutic to define Transmissibility vaccination Vaccine Vaccines variant variants Viral viral replication VoC WHO World Health Organization [DOI] 10.1111/joim.13478 PMC 바로가기 [Article Type] Review
Efficacy and safety of favipiravir plus interferon-beta versus lopinavir/ritonavir plus interferon-beta in moderately ill patients with COVID-19: A randomized clinical trialRandomized Controlled Trial Published on 2022-07-012022-10-05 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 임상, [키워드] Adverse adverse event adverse events Antiviral Antiviral agents clinical Combination combination regimen combination therapy COVID-19 Day demonstrated Efficacy Efficacy and safety event examined Favipiravir FVP group groups hospital ICU admission ill patient in-hospital mortality incidence interferon Interferon-beta IQR LOS median Mild not different not significantly different Patient Potential treatment primary endpoint randomization Randomized randomized clinical trial Randomly receive Registered registry SARS-coronavirus SARS-CoV-2 Seven single-center Treatment treatment regimen Trial viral clearance [DOI] 10.1002/jmv.27724 PMC 바로가기 [Article Type] Randomized Controlled Trial
Diagnosis and treatment of influenza based on health insurance claims between the 2010-2011 and 2019-2020 influenza seasons in Japan일본의 2010-2011년과 2019-2020년 인플루엔자 시즌 사이의 건강 보험 청구를 기반으로 한 인플루엔자 진단 및 치료Article Published on 2022-07-012022-09-11 Journal: Influenza and Other Respiratory Viruses [Category] 치료제, [키워드] anti-influenza drug anti-influenza drugs Antiviral Antiviral agents COVID-19 COVID-19 pandemic database diagnosed Diagnosis diagnostic diagnostic test diagnostic testing diagnostic tests Health healthcare healthcare administrative claims increase in Infection Influenza Influenza virus information Japan majority medication Most patient Most patients Patient provide Quantitative Treatment treatment of influenza virus infection [DOI] 10.1111/irv.12977 PMC 바로가기 [Article Type] Article
The Nucleoside/Nucleotide Analogs Tenofovir and Emtricitabine Are Inactive against SARS-CoV-2뉴클레오사이드/뉴클레오타이드 유사체 테노포비르와 엠트리시타빈은 SARS-CoV-2에 대해 비활성입니다Article Published on 2022-06-302022-09-11 Journal: Molecules [Category] COVID19(2023년), SARS, 치료제, [키워드] accelerated active site acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antiviral activity antiviral agent Antiviral agents Antiviral effect approaches approved approved drug biochemical causative pathogen caution Cell clinicians and researcher Concentration coronavirus COVID-19 COVID-19 pandemic demonstrated Efficiency emtricitabine epithelial FTC HIV-1 HIV-1 NRTI human lung in vitro data inactive indicate inhibitor lack metabolite NHBE NTP nucleoside polymerase Prevent RdRP RdRp active site required reverse transcriptase RNA polymerase SARS-CoV-2 SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus TAF TDF tenofovir Tenofovir alafenamide the SARS-CoV-2 transcriptase treat unlikely [DOI] 10.3390/molecules27134212 PMC 바로가기 [Article Type] Article
Vitamin D Endocrine System and COVID-19: Treatment with Calcifediol비타민 D 내분비계와 코로나19: 칼시페디올로 치료Review Published on 2022-06-292022-09-11 Journal: Nutrients [Category] COVID19(2023년), SARS, 변종, 신약개발, 치료제, [키워드] 25OHD 25OHD deficiency 25OHD level 25OHD levels acute respiratory distress acute respiratory distress syndrome addition Admission angiotensin antimicrobial peptides Antiviral Antiviral agents approved ARDS association autophagy bradykinin calcifediol calcitriol Characteristics chemokine cholecalciferol coagulability complications Course Coverage COVID-19 COVID-19 pandemic Critical death described develop dose doses drug early stage early stages Effect effector mechanisms Endocrine endocrine system ENhance epithelial Evidence functional High dose Host hyperinflammatory phase ICU ICU admission include increased coagulability indication Infection integrity intensive care intensive care unit intervention study mechanical ventilation modulating mortality rate neutrophil Patient patients with SARS-CoV-2 pharmacokinetic pilot study prohormone prothrombotic public health systems RAAS reactive reduce Renin repositioning respiratory distress Respiratory distress syndrome risk SARS-CoV-2 SARS-COV-2 infection serum severe COVID-19 significantly subsequent syndrome System the disease therapeutic options Treatment treatment of COVID-19 vaccination variant VDES viral evolution Vitamin Vitamin D vitamin D endocrine system vitamin D endocrine system. [DOI] 10.3390/nu14132716 PMC 바로가기 [Article Type] Review
Sequence-Specific Features of Short Double-Strand, Blunt-End RNAs Have RIG-I- and Type 1 Interferon-Dependent or -Independent Anti-Viral Effects짧은 이중 가닥, 평활 말단 RNA의 서열 특이적 특징은 RIG-I 및 유형 1 인터페론 의존성 또는 독립적 항바이러스 효과를 갖는다Article Published on 2022-06-282022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료법, 치료제, [키워드] adaptors Adenovirus Anti-viral anti-viral effect Antiviral Antiviral agents Antiviral effect antiviral effects assays Cell cell cycle cell cycle genes cell line cells cellular complementary cytoplasmic DNA DNA virus downregulated dsRNA dsRNAs Effect elicited fibroblast Gene Expression H3N2 human airway IFN IFN-alpha IFN-I IFNAR2 independent independent of indicated Infection Influenza influenza A influenza A virus Influenza virus interferon knock-out library MDA5 mechanism mimicking molecular patterns MYD88 organism Organisms pathogen pathogen-associated molecular patterns Pathogens Randomized receptor required retinoic acid retinoic acid-inducible gene I RIG-I RNA RNA therapy RNA virus RNAs SARS-CoV-2 sequence short double-strand blunt-end RNA. transcriptomics transfection Type ZNFX1 [DOI] 10.3390/v14071407 PMC 바로가기 [Article Type] Article