Antigenic cross-reactivity among human, swine, rabbit and avian hepatitis E virus capsid proteinsArticle Published on 2022-02-012023-06-11 Journal: Veterinary microbiology [Category] E형 간염, [키워드] Antigenic relation Capsid protein Common epitopes cross-reactivity hepatitis E virus [DOI] 10.1016/j.vetmic.2022.109331
SARS-CoV-2 Cross-Reactivity in Prepandemic Serum from Rural Malaria-Infected Persons, Cambodia캄보디아 농촌 말라리아 감염자의 전염병 전 혈청에서 SARS-CoV-2 교차 반응성Dispatch Published on 2022-02-012022-09-12 Journal: Emerging Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 말라리아, 진단, [키워드] acute respiratory syndrome Affect antigens Cambodia coronavirus coronavirus disease COVID-19 cross-reactivity demonstrated domain IgG Interpretation malaria Mekong pathogen SARS-CoV-2 Serosurvey Serosurveys severe acute respiratory syndrome coronavirus 2 vector-borne infections viruses zoonoses [DOI] 10.3201/eid2802.211725 PMC 바로가기 [Article Type] Dispatch
Gut power: Modulation of human amyloid formation by amyloidogenic proteins in the gastrointestinal tractReview article Published on 2022-02-012022-10-05 Journal: Current opinion in structural biology [Category] 비임상, [키워드] alpha-synuclein Brain cell death cross-reactivity disease expressed fiber Functional amyloids gastrointestinal tract Gut initial interactions mechanism Microbiome microbiota modulate neurodegenerative disorders occur Parkinson's Disease Protein secreted [DOI] 10.1016/j.sbi.2021.07.009 [Article Type] Review article
Heterologous Immunity Between SARS-CoV-2 and Pathogenic BacteriaImmunology Published on 2022-01-272022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] Activation acute respiratory syndrome Asymptomatic Bacterial bacterial pathogen bystander CD69 Cell co-culture coronavirus coronavirus disease COVID-19 cross-reactive cross-reactivity cytokine production Donor Effect elicited explain extension Heterologous heterologous immunity high variability IFN-γ IL-2 Immunity in silico in vitro individual induce mechanism memory T memory T cell non-structural protein offered outcome outcomes pathogen pathogenic bacteria peptide peptides proliferation recall recognize response SARS-CoV-2 SARS-CoV-2 peptide SARS-CoV-2 vaccination SARS-CoV-2 vaccine sequence homology severity Spike protein T cell T cell response tested the SARS-CoV-2 the spike protein TNF vaccination [DOI] 10.3389/fimmu.2022.821595 PMC 바로가기 [Article Type] Immunology
[Characterization of a monoclonal antibody against the hemagglutinin stem of H7N9 subtype avian influenza virus]Article Published on 2022-01-252023-06-22 Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology [Category] 조류인플루엔자, [키워드] antigenic epitope Avian influenza virus cross-reactivity hemagglutinin stem monoclonal antibody [DOI] 10.13345/j.cjb.210173
Structure Based Affinity Maturation and Characterizing of SARS-CoV Antibody CR3022 against SARS-CoV-2 by Computational and Experimental ApproachesArticle Published on 2022-01-192022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] affinity against SARS-CoV antibody antibody affinity approach Autoimmune binding binding free energy CDRs complementarity-determining region conserved Coronaviruses COVID-19 COVID-19 epidemic CR3022 criteria cross-react cross-reactivity demonstrated drug ELISA enzyme-linked immunosorbent experiments higher affinity hydrophobic interactions IMPROVE in vitro indicate MM/PBSA molecular molecular dynamics (MD) simulation Molecular simulation mutant mutate mutated Mutation neutralizing antibody performed plasma powerful tool provided RBD reactivity Receptor-binding domain (RBD) recognizing residue salt-bridge SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RBD selected significantly SPR Structure the binding affinity Treatment wild-type [DOI] 10.3390/v14020186 PMC 바로가기 [Article Type] Article
Large-Scale Structure-Based Screening of Potential T Cell Cross-Reactivities Involving Peptide-Targets From BCG Vaccine and SARS-CoV-2BCG 백신 및 SARS-CoV-2의 펩티드 표적과 관련된 잠재적 T 세포 교차 반응성의 대규모 구조 기반 스크리닝Immunology Published on 2022-01-132022-09-11 Journal: Frontiers in Immunology [Category] 변종, [키워드] acute respiratory syndrome coronavirus Affect arising Bacillus Bacillus Calmette-Guérin BCG BCG vaccination bcg vaccine can be used caused clinical trials computational method conducted coronavirus coronavirus 2 Coronaviruses country Coverage COVID-19 cases COVID-19 pandemic cross-reactive cross-reactivity dataset death driving Evidence expand Heterologous high-density highlight HLA human leukocyte antigen Human Leukocyte Antigens identify Immunity immunogenic in silico in some infected cells involved Involving leukocyte list Lymphocytes other coronaviruses pandemic peptide peptides Potential produced provided recognize reduced reservoir respiratory responsible risk SARS-CoV-2 screened Screening severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity of COVID-19 Spread structural bioinformatics Structure structure-based screening suggested T cell target targets therapeutic strategy vaccination Vaccine Vaccine development variant variants Viral [DOI] 10.3389/fimmu.2021.812176 PMC 바로가기 [Article Type] Immunology
Immune response to SARS-CoV-2 variants: A focus on severity, susceptibility, and preexisting immunityReview Published on 2022-01-132023-06-14 Journal: Journal of infection and public health [Category] COVID19(2023년), MERS, SARS, [키워드] antibody-dependent enhancement (ADE) COVID-19 cross-reactivity SARS-CoV-2 severity variants of concern [DOI] 10.1016/j.jiph.2022.01.007 PMC 바로가기 [Article Type] Review
Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizersSARS-CoV-2 엘리트 중화제에서 초강력 광범위 중화 항체 발견Article Published on 2022-01-122022-09-11 Journal: Cell Host & Microbe [Category] Fulltext, SARS, 변종, 진단, [키워드] Analysis analyzed antibodies antibody Antibody Response assembly B.1.1.7 B.1.351 B.1.429 B.1.617 B.1.617.2 binding broadly neutralizing antibodies candidate conformation convalescent individual convalescent individuals COVID-19 cross-reactive cross-reactivity cryo cryo-EM Cryo-EM analysis displaying effective emerging variants flexible fraction humoral IGHV3-53 monoclonal monoclonal antibodies neutralized Neutralizing Neutralizing antibodies neutralizing antibody performed predicted Prevent sarbecovirus SARS-CoV-1 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 sequence SARS-CoV-2 variants single B cell the RBD treat ultrapotent monoclonal antibodies variant variants variants of concern [DOI] 10.1016/j.chom.2021.12.010 PMC 바로가기 [Article Type] Article
mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variantResearch article Published on 2022-01-062022-10-05 Journal: Cell [Category] 변종, [키워드] Ad26.COV2.S vaccine addition BNT162b booster breadth COVID-19 cross-reactivity Delta dose exhibited highlight Humoral immunity individual induce infect Infectivity mRNA mRNA vaccine mRNA-1273 mRNA-based COVID-19 vaccine Mutation neutralization neutralization potency Neutralizing antibodies Neutralizing antibody response neutralizing antibody responses neutralizing immunity omicron other variant pseudovirus recent recipient SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pseudoviruses SARS-CoV-2 variants sera spike Spike protein Surveillance tested the SARS-CoV-2 undetectable vaccination vaccinees variant variants wild type wild-type [DOI] 10.1016/j.cell.2021.12.033 [Article Type] Research article